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What phenomenon can occur in case of using a combination of drugs?
a) Tolerance
b) Tachyphylaxis
c) Accumulation
d) Synergism
d) Synergism
d) Synergism
See lessIdiosyncratic reaction of a drug is:
a) A type of hypersensitivity reaction
b) A type of drug antagonism
c) Unpredictable, inherent, qualitatively abnormal reaction to a drug
d) Quantitatively exaggerated response
c) Unpredictable, inherent, qualitatively abnormal reaction to a drug
c) Unpredictable, inherent, qualitatively abnormal reaction to a drug
See lessWhich effect may lead to toxic reactions when a drug is taken continuously or repeatedly?
a) Refractoriness
b) Cumulative effect
c) Tolerance
d) Tachyphylaxis
b) Cumulative effect
b) Cumulative effect
See lessThe substance binding to one receptor sub type as an agonist and to another as an antagonist is called:
a) Competitive antagonist
b) Irreversible antagonist
c) Agonist-antagonist
d) Partial agonist
c) Agonist-antagonist
c) Agonist-antagonist
See lessTolerance and drug resistance can be a consequence of:
a) Drug dependence
b) Increased metabolic degradation
c) Depressed renal drug excretion
d) Activation of a drug after hepatic first-pass
b) Increased metabolic degradation
b) Increased metabolic degradation
See lessTachyphylaxis is:
a) A drug interaction between two similar types of drugs
b) Very rapidly developing tolerance
c) A decrease in responsiveness to a drug, taking days or weeks to develop
d) None of the above
b) Very rapidly developing tolerance
b) Very rapidly developing tolerance
See lessTarget proteins which a drug molecule binds are:
a) Only receptors
b) Only ion channels
c) Only carriers
d) All of the above
d) All of the above
d) All of the above
See lessTherapeutic index (TI) is:
a) A ratio used to evaluate the safety and usefulness of a drug for indication
b) A ratio used to evaluate the effectiveness of a drug
c) A ratio used to evaluate the bio availability of a drug
d) A ratio used to evaluate the elimination of a drug
a) A ratio used to evaluate the safety and usefulness of a drug for indication
a) A ratio used to evaluate the safety and usefulness of a drug for indication
See lessThe situation when failure to continue administering the drug results in serious psychological and somatic disturbances is called?
a) Tachyphylaxis
b) Sensibilization
c) Abstinence syndrome
d) Idiosyncrasy
c) Abstinence syndrome
c) Abstinence syndrome
See lessIf an agonist can produce sub maximal effects and has moderate efficacy it’s called:
a) Partial agonist
b) Antagonist
c) Agonist-antagonist
d) Full agonist
a) Partial agonist
a) Partial agonist
See less