 
			 
			MCQOPTIONS
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				This section includes 92 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Which of following charge is present in phosphate end of DNA? | 
| A. | negative | 
| B. | positive | 
| C. | neutral | 
| D. | no charge | 
| Answer» B. positive | |
| 2. | Which of following enzymes unwinds and separates DNA strands during replication? | 
| A. | helicase | 
| B. | proteases | 
| C. | topoisomerase | 
| D. | telomerase | 
| Answer» B. proteases | |
| 3. | How many DNA repair enzymes have been found so far in E Coli? | 
| A. | 1000 | 
| B. | 130 | 
| C. | 32 | 
| D. | 12 | 
| Answer» C. 32 | |
| 4. | Which of following is not a part of three models that were proposed for DNA replication? | 
| A. | semi conservative | 
| B. | destructive | 
| C. | conservative | 
| D. | dispersive | 
| Answer» C. conservative | |
| 5. | Which of following forms chromatin takes when cell enters metaphase stage? | 
| A. | diffused mass | 
| B. | looped domains | 
| C. | coiled | 
| D. | supercoiled | 
| Answer» D. supercoiled | |
| 6. | Less compacted and more disperse form of DNA is called | 
| A. | Euchromatin | 
| B. | heterochromatin | 
| C. | clumped chromatin | 
| D. | diffused chromatin | 
| Answer» B. heterochromatin | |
| 7. | Amount of which of following bases is equal to amount Cytosine? | 
| A. | thymine | 
| B. | guanine | 
| C. | adenine | 
| D. | uracil | 
| Answer» C. adenine | |
| 8. | In which of following secondary structures DNA molecule is folded? | 
| A. | alpha helix | 
| B. | beta sheets | 
| C. | random coil | 
| D. | hairpin loops | 
| Answer» B. beta sheets | |
| 9. | Patients with Xeroderma pigmentosum are sensitive to which of following? | 
| A. | peanuts | 
| B. | water | 
| C. | sunlight | 
| D. | grass | 
| Answer» D. grass | |
| 10. | How many primers, leading strand requires to elongate new strand? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» B. 2 | |
| 11. | Which of following enzymes synthesizes RNA primers? | 
| A. | protease | 
| B. | topoisomerase | 
| C. | primase | 
| D. | RNAse | 
| Answer» D. RNAse | |
| 12. | Which of following proposed double helix structure of DNA? | 
| A. | Mendel | 
| B. | Marie curie | 
| C. | Watson and crick | 
| D. | Carl Correns | 
| Answer» D. Carl Correns | |
| 13. | Which of following histones is not found in chromatin? | 
| A. | h1 | 
| B. | h2a | 
| C. | h2b | 
| D. | h3 | 
| Answer» B. h2a | |
| 14. | How many layers of base pairs is present in every turn of helix? | 
| A. | 2 | 
| B. | 4 | 
| C. | 5 | 
| D. | 10 | 
| Answer» E. | |
| 15. | How many nucleotide pairs are present in DNA of a single human cell? | 
| A. | 6 billion | 
| B. | 6 million | 
| C. | 60 million | 
| D. | 2 billion | 
| Answer» B. 6 million | |
| 16. | Which of following bases binds with adenine? | 
| A. | thymine | 
| B. | cytosine | 
| C. | guanine | 
| D. | uracil | 
| Answer» B. cytosine | |
| 17. | In which of following is telomerase most active and hence telomeres are at maximum? | 
| A. | somatic cells | 
| B. | germ cells | 
| C. | heart cells | 
| D. | none of above | 
| Answer» C. heart cells | |
| 18. | During interphase structure of chromatin is | 
| A. | coiled | 
| B. | diffused mass | 
| C. | supercoiled | 
| D. | looped | 
| Answer» C. supercoiled | |
| 19. | If unwound, one DNA molecule would be how long? | 
| A. | 1 m | 
| B. | 10 cm | 
| C. | 5 cm | 
| D. | 4 cm | 
| Answer» E. | |
| 20. | Telomeres are present at which position along chromosome? | 
| A. | middle | 
| B. | ends | 
| C. | near the middle | 
| D. | randomly placed | 
| Answer» C. near the middle | |
| 21. | What ratio of histones is positively charged? | 
| A. | 1/5th | 
| B. | 1/6th | 
| C. | 1/10th | 
| D. | 1/100th | 
| Answer» B. 1/6th | |
| 22. | Which of following is basic unit of DNA packaging? | 
| A. | chromatin | 
| B. | alpha helix | 
| C. | nucleus | 
| D. | nucleosome | 
| Answer» E. | |
| 23. | Histones are made up of approximately how many amino acids? | 
| A. | 200 | 
| B. | 100 | 
| C. | 500 | 
| D. | 10 | 
| Answer» C. 500 | |
| 24. | Which of following is a DNA repair system? | 
| A. | DNA joining | 
| B. | nucleotide excision repair | 
| C. | Repairase | 
| D. | DNA binding | 
| Answer» C. Repairase | |
| 25. | Telomeres typically contain which of following? | 
| A. | short repeats | 
| B. | genes | 
| C. | poly a tail | 
| D. | poly t tail | 
| Answer» B. genes | |
| 26. | Purine bases have how many rings in their structure? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» C. 3 | |
| 27. | Why was purine-purine bonding theory not consistent with X-Ray diffraction data? | 
| A. | it was too wide | 
| B. | it was too narrow | 
| C. | purines cannot bond together | 
| D. | it would tilt sideways | 
| Answer» B. it was too narrow | |
| 28. | What is string of DNA between two nucleosomes called? | 
| A. | attachment DNA | 
| B. | linker DNA | 
| C. | pure DNA | 
| D. | connecting DNA | 
| Answer» C. pure DNA | |
| 29. | Which of following removes RNA nucleotides of primer from 5 prime ends and replaces them with DNA nucleotides? | 
| A. | topoisomerase | 
| B. | helicase | 
| C. | single strand binding proteins | 
| D. | DNA polymerase I | 
| Answer» E. | |
| 30. | How many DNA molecules are present in nucleus of a single human cell? | 
| A. | 23 | 
| B. | 45 | 
| C. | 46 | 
| D. | 12 | 
| Answer» D. 12 | |
| 31. | Virus that infects bacteria are called | 
| A. | Bacteriovirus | 
| B. | bacteriophage | 
| C. | viral phage | 
| D. | nano viruses | 
| Answer» C. viral phage | |
| 32. | Which of following structures of 30 nm fiber is present in 300 nm fiber? | 
| A. | sheets | 
| B. | looped domains | 
| C. | helix | 
| D. | hairpin loops | 
| Answer» C. helix | |
| 33. | Which of following is not a part of a DNA molecule | 
| A. | pentose sugar | 
| B. | nitrogenous base | 
| C. | ribose sugar | 
| D. | phosphate group | 
| Answer» D. phosphate group | |
| 34. | For their experiments, Hershey and Chase tagged phage DNA with which of following radioactive isotopes? | 
| A. | sulphur | 
| B. | sodium | 
| C. | phosphorus | 
| D. | radium | 
| Answer» D. radium | |
| 35. | Which of following bases binds with cytosine? | 
| A. | uracil | 
| B. | guanine | 
| C. | thymine | 
| D. | adenine | 
| Answer» C. thymine | |
| 36. | In which of following directions, two backbones of DNA molecule runs? | 
| A. | parallel | 
| B. | anti parallel | 
| C. | intersecting | 
| D. | rounded | 
| Answer» C. intersecting | |
| 37. | What is rate of elongation of DNA in bacteria? | 
| A. | 100 per second | 
| B. | 500 per second | 
| C. | 20 per second | 
| D. | 1 per second | 
| Answer» C. 20 per second | |
| 38. | In E Coli, replication of chromosomes starts at a particular site called | 
| A. | start of replication | 
| B. | initiation of replication | 
| C. | start point | 
| D. | origin of replication | 
| Answer» E. | |
| 39. | In making if 30nm fiber of DNA, which of following histones are involved? | 
| A. | h1 | 
| B. | h2a | 
| C. | h2b | 
| D. | h3 | 
| Answer» B. h2a | |
| 40. | Amount of which of following bases is equal to amount Thymine? | 
| A. | adenine | 
| B. | uracil | 
| C. | guanine | 
| D. | cytosine | 
| Answer» B. uracil | |
| 41. | What is process of tagging each chromosome with molecular tags so each chromosome has a different color, called? | 
| A. | coloring | 
| B. | painting | 
| C. | tagging | 
| D. | marking | 
| Answer» C. tagging | |
| 42. | How many phosphate groups are lost from DNA as each monomer joins? | 
| A. | 2 | 
| B. | 4 | 
| C. | 6 | 
| D. | 8 | 
| Answer» B. 4 | |
| 43. | Segments of DNA synthesized along lagging strand are called | 
| A. | replication fragment | 
| B. | okazaki fragments | 
| C. | lagging fragments | 
| D. | leading fragments | 
| Answer» C. lagging fragments | |
| 44. | Telomeres from cells that have formed tumors have which of following quality? | 
| A. | unusually short | 
| B. | unusually long | 
| C. | same length | 
| D. | absent | 
| Answer» B. unusually long | |
| 45. | Which of following bases can make dimers if they're adjacent to a DNA molecule? | 
| A. | thymine | 
| B. | adenine | 
| C. | cytosine | 
| D. | uracil | 
| Answer» B. adenine | |
| 46. | In which of following direction a new DNA molecule is elongated by polymerase? | 
| A. | 5 to 3 end | 
| B. | 3 to 5 end | 
| C. | no direction | 
| D. | along the template strand | 
| Answer» B. 3 to 5 end | |
| 47. | From which of following a new DNA template starts? | 
| A. | 3 prime end of primer | 
| B. | 5 prime end of DNA | 
| C. | 5 prime end of primer | 
| D. | 3 prime end of DNA | 
| Answer» B. 5 prime end of DNA | |
| 48. | Which of following is infected by T2 phage? | 
| A. | e coli | 
| B. | immune system | 
| C. | thermophile bacteria | 
| D. | nervous system | 
| Answer» B. immune system | |
| 49. | What is diameter of a nucleosome? | 
| A. | 5 nm | 
| B. | 3 nm | 
| C. | 2 nm | 
| D. | 10 nm | 
| Answer» E. | |
| 50. | How many types of histones are most commonly found in chromatin? | 
| A. | 2 | 
| B. | 3 | 
| C. | 4 | 
| D. | 5 | 
| Answer» D. 5 | |