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This section includes 92 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of following charge is present in phosphate end of DNA? |
| A. | negative |
| B. | positive |
| C. | neutral |
| D. | no charge |
| Answer» B. positive | |
| 2. |
Which of following enzymes unwinds and separates DNA strands during replication? |
| A. | helicase |
| B. | proteases |
| C. | topoisomerase |
| D. | telomerase |
| Answer» B. proteases | |
| 3. |
How many DNA repair enzymes have been found so far in E Coli? |
| A. | 1000 |
| B. | 130 |
| C. | 32 |
| D. | 12 |
| Answer» C. 32 | |
| 4. |
Which of following is not a part of three models that were proposed for DNA replication? |
| A. | semi conservative |
| B. | destructive |
| C. | conservative |
| D. | dispersive |
| Answer» C. conservative | |
| 5. |
Which of following forms chromatin takes when cell enters metaphase stage? |
| A. | diffused mass |
| B. | looped domains |
| C. | coiled |
| D. | supercoiled |
| Answer» D. supercoiled | |
| 6. |
Less compacted and more disperse form of DNA is called |
| A. | Euchromatin |
| B. | heterochromatin |
| C. | clumped chromatin |
| D. | diffused chromatin |
| Answer» B. heterochromatin | |
| 7. |
Amount of which of following bases is equal to amount Cytosine? |
| A. | thymine |
| B. | guanine |
| C. | adenine |
| D. | uracil |
| Answer» C. adenine | |
| 8. |
In which of following secondary structures DNA molecule is folded? |
| A. | alpha helix |
| B. | beta sheets |
| C. | random coil |
| D. | hairpin loops |
| Answer» B. beta sheets | |
| 9. |
Patients with Xeroderma pigmentosum are sensitive to which of following? |
| A. | peanuts |
| B. | water |
| C. | sunlight |
| D. | grass |
| Answer» D. grass | |
| 10. |
How many primers, leading strand requires to elongate new strand? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» B. 2 | |
| 11. |
Which of following enzymes synthesizes RNA primers? |
| A. | protease |
| B. | topoisomerase |
| C. | primase |
| D. | RNAse |
| Answer» D. RNAse | |
| 12. |
Which of following proposed double helix structure of DNA? |
| A. | Mendel |
| B. | Marie curie |
| C. | Watson and crick |
| D. | Carl Correns |
| Answer» D. Carl Correns | |
| 13. |
Which of following histones is not found in chromatin? |
| A. | h1 |
| B. | h2a |
| C. | h2b |
| D. | h3 |
| Answer» B. h2a | |
| 14. |
How many layers of base pairs is present in every turn of helix? |
| A. | 2 |
| B. | 4 |
| C. | 5 |
| D. | 10 |
| Answer» E. | |
| 15. |
How many nucleotide pairs are present in DNA of a single human cell? |
| A. | 6 billion |
| B. | 6 million |
| C. | 60 million |
| D. | 2 billion |
| Answer» B. 6 million | |
| 16. |
Which of following bases binds with adenine? |
| A. | thymine |
| B. | cytosine |
| C. | guanine |
| D. | uracil |
| Answer» B. cytosine | |
| 17. |
In which of following is telomerase most active and hence telomeres are at maximum? |
| A. | somatic cells |
| B. | germ cells |
| C. | heart cells |
| D. | none of above |
| Answer» C. heart cells | |
| 18. |
During interphase structure of chromatin is |
| A. | coiled |
| B. | diffused mass |
| C. | supercoiled |
| D. | looped |
| Answer» C. supercoiled | |
| 19. |
If unwound, one DNA molecule would be how long? |
| A. | 1 m |
| B. | 10 cm |
| C. | 5 cm |
| D. | 4 cm |
| Answer» E. | |
| 20. |
Telomeres are present at which position along chromosome? |
| A. | middle |
| B. | ends |
| C. | near the middle |
| D. | randomly placed |
| Answer» C. near the middle | |
| 21. |
What ratio of histones is positively charged? |
| A. | 1/5th |
| B. | 1/6th |
| C. | 1/10th |
| D. | 1/100th |
| Answer» B. 1/6th | |
| 22. |
Which of following is basic unit of DNA packaging? |
| A. | chromatin |
| B. | alpha helix |
| C. | nucleus |
| D. | nucleosome |
| Answer» E. | |
| 23. |
Histones are made up of approximately how many amino acids? |
| A. | 200 |
| B. | 100 |
| C. | 500 |
| D. | 10 |
| Answer» C. 500 | |
| 24. |
Which of following is a DNA repair system? |
| A. | DNA joining |
| B. | nucleotide excision repair |
| C. | Repairase |
| D. | DNA binding |
| Answer» C. Repairase | |
| 25. |
Telomeres typically contain which of following? |
| A. | short repeats |
| B. | genes |
| C. | poly a tail |
| D. | poly t tail |
| Answer» B. genes | |
| 26. |
Purine bases have how many rings in their structure? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 27. |
Why was purine-purine bonding theory not consistent with X-Ray diffraction data? |
| A. | it was too wide |
| B. | it was too narrow |
| C. | purines cannot bond together |
| D. | it would tilt sideways |
| Answer» B. it was too narrow | |
| 28. |
What is string of DNA between two nucleosomes called? |
| A. | attachment DNA |
| B. | linker DNA |
| C. | pure DNA |
| D. | connecting DNA |
| Answer» C. pure DNA | |
| 29. |
Which of following removes RNA nucleotides of primer from 5 prime ends and replaces them with DNA nucleotides? |
| A. | topoisomerase |
| B. | helicase |
| C. | single strand binding proteins |
| D. | DNA polymerase I |
| Answer» E. | |
| 30. |
How many DNA molecules are present in nucleus of a single human cell? |
| A. | 23 |
| B. | 45 |
| C. | 46 |
| D. | 12 |
| Answer» D. 12 | |
| 31. |
Virus that infects bacteria are called |
| A. | Bacteriovirus |
| B. | bacteriophage |
| C. | viral phage |
| D. | nano viruses |
| Answer» C. viral phage | |
| 32. |
Which of following structures of 30 nm fiber is present in 300 nm fiber? |
| A. | sheets |
| B. | looped domains |
| C. | helix |
| D. | hairpin loops |
| Answer» C. helix | |
| 33. |
Which of following is not a part of a DNA molecule |
| A. | pentose sugar |
| B. | nitrogenous base |
| C. | ribose sugar |
| D. | phosphate group |
| Answer» D. phosphate group | |
| 34. |
For their experiments, Hershey and Chase tagged phage DNA with which of following radioactive isotopes? |
| A. | sulphur |
| B. | sodium |
| C. | phosphorus |
| D. | radium |
| Answer» D. radium | |
| 35. |
Which of following bases binds with cytosine? |
| A. | uracil |
| B. | guanine |
| C. | thymine |
| D. | adenine |
| Answer» C. thymine | |
| 36. |
In which of following directions, two backbones of DNA molecule runs? |
| A. | parallel |
| B. | anti parallel |
| C. | intersecting |
| D. | rounded |
| Answer» C. intersecting | |
| 37. |
What is rate of elongation of DNA in bacteria? |
| A. | 100 per second |
| B. | 500 per second |
| C. | 20 per second |
| D. | 1 per second |
| Answer» C. 20 per second | |
| 38. |
In E Coli, replication of chromosomes starts at a particular site called |
| A. | start of replication |
| B. | initiation of replication |
| C. | start point |
| D. | origin of replication |
| Answer» E. | |
| 39. |
In making if 30nm fiber of DNA, which of following histones are involved? |
| A. | h1 |
| B. | h2a |
| C. | h2b |
| D. | h3 |
| Answer» B. h2a | |
| 40. |
Amount of which of following bases is equal to amount Thymine? |
| A. | adenine |
| B. | uracil |
| C. | guanine |
| D. | cytosine |
| Answer» B. uracil | |
| 41. |
What is process of tagging each chromosome with molecular tags so each chromosome has a different color, called? |
| A. | coloring |
| B. | painting |
| C. | tagging |
| D. | marking |
| Answer» C. tagging | |
| 42. |
How many phosphate groups are lost from DNA as each monomer joins? |
| A. | 2 |
| B. | 4 |
| C. | 6 |
| D. | 8 |
| Answer» B. 4 | |
| 43. |
Segments of DNA synthesized along lagging strand are called |
| A. | replication fragment |
| B. | okazaki fragments |
| C. | lagging fragments |
| D. | leading fragments |
| Answer» C. lagging fragments | |
| 44. |
Telomeres from cells that have formed tumors have which of following quality? |
| A. | unusually short |
| B. | unusually long |
| C. | same length |
| D. | absent |
| Answer» B. unusually long | |
| 45. |
Which of following bases can make dimers if they're adjacent to a DNA molecule? |
| A. | thymine |
| B. | adenine |
| C. | cytosine |
| D. | uracil |
| Answer» B. adenine | |
| 46. |
In which of following direction a new DNA molecule is elongated by polymerase? |
| A. | 5 to 3 end |
| B. | 3 to 5 end |
| C. | no direction |
| D. | along the template strand |
| Answer» B. 3 to 5 end | |
| 47. |
From which of following a new DNA template starts? |
| A. | 3 prime end of primer |
| B. | 5 prime end of DNA |
| C. | 5 prime end of primer |
| D. | 3 prime end of DNA |
| Answer» B. 5 prime end of DNA | |
| 48. |
Which of following is infected by T2 phage? |
| A. | e coli |
| B. | immune system |
| C. | thermophile bacteria |
| D. | nervous system |
| Answer» B. immune system | |
| 49. |
What is diameter of a nucleosome? |
| A. | 5 nm |
| B. | 3 nm |
| C. | 2 nm |
| D. | 10 nm |
| Answer» E. | |
| 50. |
How many types of histones are most commonly found in chromatin? |
| A. | 2 |
| B. | 3 |
| C. | 4 |
| D. | 5 |
| Answer» D. 5 | |