MCQOPTIONS
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MCQOPTIONS
This section includes 89 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Calcium acts as an intracellular messenger. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 2. |
Cyclic AMP can inhibit the growth of cells. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 3. |
Ryanodine is a _______________ |
| A. | protein |
| B. | bacteria |
| C. | alkaloid |
| D. | steroid |
| Answer» D. steroid | |
| 4. |
Activation of P13K in adherent epithelial cell promotes ___________________ |
| A. | glucose translocation |
| B. | cell survival |
| C. | cell transformation |
| D. | signal transduction |
| Answer» C. cell transformation | |
| 5. |
Fura-2 is an example of __________________ |
| A. | fluorescent molecule |
| B. | cell surface receptor |
| C. | cell surface antigen |
| D. | oncogene |
| Answer» B. cell surface receptor | |
| 6. |
Inactivation of which of the following leads to shrinkage of the nucleus? |
| A. | lamin |
| B. | tubulin |
| C. | actin |
| D. | gelsolin |
| Answer» B. tubulin | |
| 7. |
Abnormal elevation of cytosolic Calcium can occur following a _____________ |
| A. | stroke |
| B. | conception |
| C. | tumor |
| D. | epilepsy |
| Answer» B. conception | |
| 8. |
Nitric oxide is an intracellular messenger. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 9. |
Which of the following does not converge to activate the same signaling pathway? |
| A. | G-protein coupled receptor |
| B. | Receptor tyrosine kinase |
| C. | Integrin |
| D. | Calmodulin |
| Answer» E. | |
| 10. |
Which of the following type of cells recognize and kill the abnormal pathogen infected cells? |
| A. | Mast cells |
| B. | B-lymphocytes |
| C. | T-lymphocytes |
| D. | Neutrophils |
| Answer» D. Neutrophils | |
| 11. |
Acetylcholine has the function of ________________________ |
| A. | muscle relaxation |
| B. | fertilizing agent |
| C. | promoting cell adhesion |
| D. | promoting cell division |
| Answer» B. fertilizing agent | |
| 12. |
How many types of calcium ion channels are present on ER membrane? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 13. |
The TNFR1 is a trimeric receptor. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 14. |
Which of the following is also termed as a death receptor? |
| A. | TNFR1 |
| B. | TNFR2 |
| C. | TNFR3 |
| D. | TNFR4 |
| Answer» B. TNFR2 | |
| 15. |
Apoptosis is programmed cell death. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 16. |
Viagra is specific for which isoform of cGMP phosphodiesterase? |
| A. | PDE2 |
| B. | PDE4 |
| C. | PDE5 |
| D. | PDE8 |
| Answer» D. PDE8 | |
| 17. |
Upon fertilization, a wave of calcium release is observed throughout the cell. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 18. |
The posttranslational modification involving nitric oxide is called __________________ |
| A. | N-nitrosylation |
| B. | P-nitrosylation |
| C. | N-glycosylation |
| D. | S-nitrosylation |
| Answer» E. | |
| 19. |
The nitric oxide binds to and stimulates guanylyl cyclase. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 20. |
Which of the following is a calcium-binding protein? |
| A. | cyclin |
| B. | calmodulin |
| C. | renin |
| D. | kinetin |
| Answer» C. renin | |
| 21. |
Binding of acetylcholine to outer surface of endothelial cells, signals _____________________ |
| A. | increase in cytosolic Ca²⁺ concentration |
| B. | decrease cytosolic Ca²⁺ concentration |
| C. | increase in acidity |
| D. | increase in basicity |
| Answer» B. decrease cytosolic Ca²⁺ concentration | |
| 22. |
The diffusible agent produced by binding of acetylcholine to endothelial cells is __________________ |
| A. | vimentin |
| B. | nitric oxide |
| C. | hydrogen peroxide |
| D. | hydrogen sulfide |
| Answer» C. hydrogen peroxide | |
| 23. |
The process by which extracellular messages translate into intracellular changes is termed _________________ |
| A. | cell signaling |
| B. | cell adhesion |
| C. | signal transduction |
| D. | cell transformation |
| Answer» D. cell transformation | |
| 24. |
Which messenger molecules are derived from arachidonic acid? |
| A. | eicosanoids |
| B. | terpenoids |
| C. | corticoids |
| D. | steroids |
| Answer» B. terpenoids | |
| 25. |
When was the term apoptosis coined? |
| A. | 1972 |
| B. | 1982 |
| C. | 1992 |
| D. | 2002 |
| Answer» B. 1982 | |
| 26. |
Steroids are derived from ________________ |
| A. | estrogen |
| B. | cholesterol |
| C. | proteins |
| D. | carbohydrates |
| Answer» C. proteins | |
| 27. |
The development of Viagra is related to the discovery of nitric oxide as a ____________________ |
| A. | secondary messenger |
| B. | gaseous compound |
| C. | primary messenger |
| D. | cyclin inhibitor |
| Answer» B. gaseous compound | |
| 28. |
CREB is a _____________________ |
| A. | transcription factor |
| B. | primary messenger |
| C. | secondary messenger |
| D. | surface receptor |
| Answer» B. primary messenger | |
| 29. |
Calmodulin has low affinity for _____________ |
| A. | magnesium ions |
| B. | iodine |
| C. | non-stimulated cells |
| D. | stimulated cells |
| Answer» D. stimulated cells | |
| 30. |
The CED3 gene product in nematodes has homologous _______________ in mammals. |
| A. | kinases |
| B. | esterases |
| C. | caspases |
| D. | endonucleases |
| Answer» D. endonucleases | |
| 31. |
Which ions activate cyclin-dependent kinases, following fertilization? |
| A. | Ca²⁺ |
| B. | Mg²⁺ |
| C. | Fe³⁺ |
| D. | H⁺ |
| Answer» B. Mg²⁺ | |
| 32. |
Nitric oxide is formed from which of the amino acid? |
| A. | L-lysine |
| B. | R-lysine |
| C. | R-arginine |
| D. | L-arginine |
| Answer» E. | |
| 33. |
G-protein coupled receptors contain ________ transmembrane alpha helices. |
| A. | 2 |
| B. | 5 |
| C. | 7 |
| D. | 9 |
| Answer» D. 9 | |
| 34. |
To which of the following residues of the protein, the protein kinases do not add phosphate groups? |
| A. | serine |
| B. | cytosine |
| C. | threonine |
| D. | tyrosine |
| Answer» C. threonine | |
| 35. |
Inactivation of which of the following leads to detachment of the apoptotic cell? |
| A. | FAK |
| B. | PKB |
| C. | PKC |
| D. | RAF1 |
| Answer» B. PKB | |
| 36. |
Cytokines serve as _____________________ for apoptosis. |
| A. | internal stimuli |
| B. | external stimuli |
| C. | inhibitors |
| D. | substitutes |
| Answer» C. inhibitors | |
| 37. |
Which of the following is an extracellular messenger of apoptosis? |
| A. | serine |
| B. | tumor necrosis factor |
| C. | ribozyme |
| D. | translation inhibitor |
| Answer» C. ribozyme | |
| 38. |
The concentration of Calcium in a resting cell is ___________ |
| A. | 10 M |
| B. | 10¯² M |
| C. | 10¯⁵ M |
| D. | 10¯⁷ M |
| Answer» E. | |
| 39. |
Which of the following compounds is metabolized into nitric oxide? |
| A. | Phosphoglycerine |
| B. | Nitroglycerine |
| C. | Sulforaphane |
| D. | Serotonin |
| Answer» C. Sulforaphane | |
| 40. |
Which receptors open up during the calcium-induced calcium release? |
| A. | Ryanodine receptors |
| B. | IP₃ receptors |
| C. | ligand-gated channels |
| D. | C₂H₂ receptors |
| Answer» B. IP₃ receptors | |
| 41. |
On the cytoplasmic site of GCPRs, the G-proteins bind to ___________________ |
| A. | amino-terminus |
| B. | promoter region |
| C. | second loop |
| D. | third loop |
| Answer» E. | |
| 42. |
The G-proteins bind only to _________________ |
| A. | cytosine |
| B. | guanine |
| C. | thymine |
| D. | adenine |
| Answer» C. thymine | |
| 43. |
Arrestins compete with ________________ for binding with G-protein coupled receptors. |
| A. | Effectors |
| B. | Primary messengers |
| C. | Secondary messengers |
| D. | G-proteins |
| Answer» E. | |
| 44. |
Desensitization is the process of blocking receptors from turning on ______________ |
| A. | G-proteins |
| B. | Transcription factors |
| C. | Promoters |
| D. | Activators |
| Answer» B. Transcription factors | |
| 45. |
Adenoma is caused by the over-secretion of ____________________ |
| A. | arrestin |
| B. | rhodopsin |
| C. | kinetin |
| D. | thyroid hormone |
| Answer» E. | |
| 46. |
Retinitis pigmentosa is an inherited disorder caused due to mutation in the gene that encodes for __________________ |
| A. | G-proteins |
| B. | Arrestin |
| C. | Rhodopsin |
| D. | G-protein receptor kinase |
| Answer» D. G-protein receptor kinase | |
| 47. |
The inactive conformation of a G-protein coupled receptor is stabilized by ____________________ |
| A. | covalent interactions |
| B. | hydrogen binding |
| C. | non-covalent interactions |
| D. | ionic interactions |
| Answer» D. ionic interactions | |
| 48. |
The G-protein coupled receptors have their _____________________ outside the cell. |
| A. | amino terminus |
| B. | carboxyl terminus |
| C. | alpha helices |
| D. | beta helices |
| Answer» B. carboxyl terminus | |
| 49. |
Which of the following is a stimulus for rhodopsin? |
| A. | light |
| B. | acidic pH |
| C. | basic pH |
| D. | neurotoxins |
| Answer» B. acidic pH | |
| 50. |
G-protein coupled receptors are referred to as seven-transmembrane receptors. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |