MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
All are true about Ifosfamide except- |
| A. | Chloracetaldehyde is active from |
| B. | Less neurotoxic than cyclophosphamide |
| C. | It is nitrogen mustard |
| D. | Metabolised by CYP3A4 to from active metabolite |
| Answer» C. It is nitrogen mustard | |
| 2. |
Inhaled nitric oxide is used - |
| A. | To prevent CNS complication |
| B. | For reducing pulmonary hypertension |
| C. | For stabilizing systemic heamodynamics |
| D. | In case of jaundice |
| Answer» C. For stabilizing systemic heamodynamics | |
| 3. |
All of the following agents are used for prophylaxis of migraine,Except |
| A. | Topiramate |
| B. | Ethosuxamide |
| C. | Propanalol |
| D. | Valproate |
| Answer» C. Propanalol | |
| 4. |
The following drug is NOT useful during acute attack of bronchial asthma - |
| A. | Salbutamol |
| B. | Hydrocortisone |
| C. | Cromolyn sodium |
| D. | Theophylline |
| Answer» D. Theophylline | |
| 5. |
Hydroxytryptophan is a precursor of |
| A. | LSD |
| B. | Epinephrine |
| C. | Norepinephrine |
| D. | Serotonin |
| Answer» E. | |
| 6. |
Immunomodulator leading to increase T-cell mediated immunity: |
| A. | Levamisole |
| B. | Interferon |
| C. | Chloroquine |
| D. | Interleukins |
| Answer» B. Interferon | |
| 7. |
All of the following are selective beta1 blockers except: |
| A. | Metroprolol |
| B. | Atenolol |
| C. | Betaxolol |
| D. | Labetalol |
| Answer» E. | |
| 8. |
Common site of regional enteritis is: |
| A. | Rectum |
| B. | Colon |
| C. | Caecum |
| D. | Distal ileum and colon |
| Answer» E. | |
| 9. |
Infraclavicular lesion of tuberculosis is known as- |
| A. | Puhl's focus |
| B. | Gohn's focus |
| C. | Simmon's focus |
| D. | Assman's focus |
| Answer» E. | |
| 10. |
Mefloquine is contraindicated with - |
| A. | Quinine |
| B. | Atenolol |
| C. | Enalapril |
| D. | Verapamil |
| Answer» B. Atenolol | |
| 11. |
Allopurinol is most likely to potentiate the pharmacological action of - |
| A. | 5 Fluorouracil |
| B. | Bleomycin |
| C. | 6-mercaptopurine |
| D. | Doxorubicin |
| Answer» D. Doxorubicin | |
| 12. |
The marker for endodermal sinus tumor is: |
| A. | Alpha-fetoprotein |
| B. | Beta HCG |
| C. | LDH |
| D. | CA-125 |
| Answer» B. Beta HCG | |
| 13. |
A 15 year old boy presented with a one day history of bleeding gums, subconjunctival bleed and purpuric rash.Investigations revealed the following results: Hb-6.4 mg/dl; TLC-26500/mm3 Platelet 35000 mm3; Prothrombin time-20 sec with a control of 13 sec; partial thromboplastin time-50 sec; and Fibrinogen 10 mg/dl.Peripheral smear was suggestive of acute myeloblastic leukemia.Which of the following is the most likely - |
| A. | Myeloblastic leukemia with maturation |
| B. | Myeloblastic leukemia without maturation |
| C. | Myelomonocytic leukemia |
| D. | Promyelocytic leukemia |
| Answer» E. | |
| 14. |
Toxic megacolon is seen in: |
| A. | Colonic diverticulosis |
| B. | Hamartomatous polyp |
| C. | Chronic nonspecific ulcerative colititis |
| D. | Crohn's disease |
| Answer» D. Crohn's disease | |
| 15. |
Two identical specimen of the intestine obtained following colectomy shows on examination hemorrhagic cobblestone appearance.One of them however,shows longitudinal grooving.It is likely to be a specimen of: |
| A. | Ulcerative colitis |
| B. | Ischemic colitis |
| C. | Multiple polyposis |
| D. | Crohn's disease |
| Answer» E. | |
| 16. |
Which of the following statements on lymphoma is not true ? |
| A. | Several types of non Hodgkin's lymphoma (NHL) may have a leukemic phase |
| B. | In general follicular(nodular) NHL has worse prognosis compared to diffuse NHL |
| C. | A single classification system for Hodgkin's disease (HD) is almost universally accepted |
| D. | HD more often tends to remain localized to a single group of lymph nodes and spreads by contiguity |
| Answer» C. A single classification system for Hodgkin's disease (HD) is almost universally accepted | |
| 17. |
Psammoma bodies may be seen in all of the following, except: |
| A. | Meningioma |
| B. | Serous cystadenocarcinoma of ovary |
| C. | Follicular carcinoma of Thyroid |
| D. | Papillary carcinoma of Thyroid |
| Answer» D. Papillary carcinoma of Thyroid | |
| 18. |
All of the following are correct about steroids except: |
| A. | Bind plasma membrane receptors and following internalization influence nuclear changes |
| B. | Inhibit the release of arachidonic acid from vessel wall through action of phospholipase A2 |
| C. | Increase glucose synthesis,glycogen deposition in liver |
| D. | Inhibit vascular membrane permeability |
| Answer» B. Inhibit the release of arachidonic acid from vessel wall through action of phospholipase A2 | |
| 19. |
SIADH is caused by all except - |
| A. | Vinblastine |
| B. | Vincristine |
| C. | Cyslophosphamide |
| D. | Actinomycin D |
| Answer» E. | |
| 20. |
Side effects of Clofazimine are all except |
| A. | Skin pigmentation |
| B. | GI disturbance |
| C. | Ichthyosis |
| D. | Anemia |
| Answer» E. | |
| 21. |
All of the following are true about Methicillin Reistance in MRSA,Except: |
| A. | Resistance may be produced by hyperproduction of Beta Lactamase |
| B. | Resistance is produced as a result of altered PBP's |
| C. | Resistance may be missed at incubation temperature of 370C during susceptibility testing |
| D. | Resistance is primarily mediated/transmitted via plasmids |
| Answer» E. | |
| 22. |
Which of the following drugs is used to reverse the effect of d-tubocurarin: |
| A. | Atropine |
| B. | Neostigmine |
| C. | Physostigmine |
| D. | Organophosphorus |
| Answer» C. Physostigmine | |
| 23. |
Effects of estrogen are all of the following ,Except |
| A. | Increases Triglycerides |
| B. | - |
| C. | Reduces HDL |
| D. | Reduces LDL |
| Answer» D. Reduces LDL | |
| 24. |
Furosemide causes all except |
| A. | Hyperuricemia |
| B. | Ototoxicity |
| C. | Hypercalcemia |
| D. | Hypokalemia |
| Answer» D. Hypokalemia | |
| 25. |
All of the following are topically used sulphonamides except: |
| A. | Sulphadiazine. |
| B. | Sulphacetamide. |
| C. | Mafenide. |
| D. | Silver sulphadiazine. |
| Answer» B. Sulphacetamide. | |
| 26. |
Which of the following is the drug of choice for PSVT |
| A. | Lignocaine |
| B. | Verapamil |
| C. | Flecainide |
| D. | Tocavide |
| Answer» C. Flecainide | |
| 27. |
A 72 year old patient with parkinsonism presents with swollen feet. They are red, tender and very painful. You could clear up these symptoms within a few days if you told the patient to stop taking - |
| A. | Amantadine |
| B. | Benztropine |
| C. | Bromocriptine |
| D. | Levodopa |
| Answer» B. Benztropine | |
| 28. |
Despite their short half lives(2 hours), Proton pumps Inhibitors(PPIs) cause a prolonged suppression of acid secretion(up to 48 hours) because - |
| A. | They are prodrugs and undergo activation gradually |
| B. | They exit from the plasma and enter acid secretory canaliculi and stay here, blocking the secretion of acid for a long time |
| C. | They irreversibly inhibit the proton pump molecule and hence, acid secretion requires synthesis of new proton pumps |
| D. | They are avilable as enteric coated capsules, from which drug is gradually released |
| Answer» D. They are avilable as enteric coated capsules, from which drug is gradually released | |
| 29. |
All of the following statements are true regarding Losartan except |
| A. | Associated with negligible cough |
| B. | Causes hyperuricemia |
| C. | It is a competitive angiotensin receptor antagonist |
| D. | It has a long acting metabolite |
| Answer» C. It is a competitive angiotensin receptor antagonist | |
| 30. |
Methyldopa is primarily used in: |
| A. | Pregnancy Induced Hypertension |
| B. | Parkinsonism |
| C. | Refractory hypertension |
| D. | Hirsuitism |
| Answer» B. Parkinsonism | |
| 31. |
All of the following statements about Trientine are true,Except |
| A. | Not given with iron within two hours of ingestion |
| B. | May cause iron deficiency anemia |
| C. | More potent than penicillamine and orally absorbed |
| D. | Alternative to penicilliamine in non tolerant |
| Answer» D. Alternative to penicilliamine in non tolerant | |
| 32. |
Drug causing icthyosis and hyperpigmentation, when used in leprosy is - |
| A. | Rifampicin |
| B. | Dapsone |
| C. | Clofazimine |
| D. | Ethionamide |
| Answer» D. Ethionamide | |
| 33. |
All of the following are therapeutic uses of penicillin G, except: |
| A. | Rickettsial infection |
| B. | Bacterial meningitis |
| C. | Anthrax |
| D. | Syphilis |
| Answer» B. Bacterial meningitis | |
| 34. |
Clonidine is a : |
| A. | Alpha2 selective agonist |
| B. | Alpha1 selective agonist |
| C. | Alpha2 selective antagonist |
| D. | Alpha1 selective antagonist |
| Answer» B. Alpha1 selective agonist | |
| 35. |
Which of the following drugs is not used for motion sickness |
| A. | Metochlopromide |
| B. | Cyclizine |
| C. | Cinnarizine |
| D. | Scopolamine |
| Answer» B. Cyclizine | |
| 36. |
Which of the following is not an adverse effect of chronic amiadarone therapy: |
| A. | Hyperthyroidism |
| B. | Systemic Lupus erythematosus |
| C. | Pulmonary Fibrosis |
| D. | Hypothyroidism |
| Answer» C. Pulmonary Fibrosis | |
| 37. |
Presence of food might be expected to interfere with drug absorption by slowing gastric emptying,or by altering the degree of ionization of the drug in the stomach.Which of the following statements is not correct example: |
| A. | Concurrent food intake may severely reduce the rate of absorption of phenytoin. |
| B. | Absorption of digoxin is delayed by the presence of food |
| C. | Antimalarial drug halofantrine is more extensively absorbed if taken with food. |
| D. | Presence of food enhances the absorption of hydrochlorthiazide. |
| Answer» E. | |
| 38. |
Tolazoline is used as |
| A. | As vasodilator in treating coronary artery stenosis during angio procedures |
| B. | As thrombin inhibitor in peripheral angiography |
| C. | Antispasmodic during biliary spasm |
| D. | As vasoconstrictor in t/t of varices |
| Answer» B. As thrombin inhibitor in peripheral angiography | |
| 39. |
Ideal drug employed in the preoperative preparation for surgical excision of pheochromocytoma is - |
| A. | Atenolol |
| B. | Phenoxybenzamine |
| C. | Reserpine |
| D. | Clonidine |
| Answer» C. Reserpine | |
| 40. |
Ampicillin causes increase in rash of: |
| A. | Erythema toxicam |
| B. | Infectious mononucleosis |
| C. | Fifth disease |
| D. | German measles |
| Answer» C. Fifth disease | |
| 41. |
Sideroblastic anemia is caused by all except: |
| A. | Paracetamol |
| B. | Phenacetin |
| C. | Cyclophosphamide |
| D. | Pyrazinamide |
| Answer» E. | |
| 42. |
For drugs with first order kinetics the time required to achieve steady state levels can be predicted from |
| A. | Volume of distribution |
| B. | Half life |
| C. | Clearance |
| D. | Loading dose |
| Answer» C. Clearance | |
| 43. |
Pentostatin acts by inhibiting - |
| A. | RNA depends DNA polymerase enzyme |
| B. | Aldolase enzyme |
| C. | Adenosine deaminase enzyme |
| D. | Adenyl cyclase enzyme |
| Answer» D. Adenyl cyclase enzyme | |
| 44. |
The most significant adverse effect of ACE inhibitions is - |
| A. | Hypertension |
| B. | Hypocalcemia |
| C. | Hypocalcemia rate |
| D. | Hypotension |
| Answer» E. | |
| 45. |
Racemic mixture of two enantiomers with different pharmacokinetic and pharmacodynamic properties is seen in: |
| A. | Dilantin |
| B. | Digoxin |
| C. | Verapamil |
| D. | Octreotide |
| Answer» D. Octreotide | |
| 46. |
All of the following are examples of bactericidal drugs except: |
| A. | Rifampicin |
| B. | INH |
| C. | Pyrazinamide |
| D. | Ethambutol |
| Answer» E. | |
| 47. |
Increased prolactin is associated with - |
| A. | Increased testosterone |
| B. | Increased estradiol |
| C. | Increased FSH |
| D. | Increased libido |
| Answer» C. Increased FSH | |
| 48. |
The non sedation antihistamines are all except one - |
| A. | Fexofenadine |
| B. | Desloratidine |
| C. | Levocetrizine |
| D. | Cinnarizine |
| Answer» E. | |
| 49. |
Which of the following drug is used for prophylaxis of migraine ? |
| A. | Diclofenac |
| B. | Flunarizine |
| C. | Sumatriptan |
| D. | Dihydroergotamine |
| Answer» C. Sumatriptan | |
| 50. |
All of the following statements about Aprepitant are true,except: |
| A. | Metabolized by CyP3A4 pathway |
| B. | Ameliorates nausea and vomiting of chemotherapy |
| C. | Agonist at Neurokinin receptor (NK1) |
| D. | Crosses the blood brain barrier |
| Answer» D. Crosses the blood brain barrier | |