MCQOPTIONS
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MCQOPTIONS
This section includes 11 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following is incorrect about ARACHNE? |
| A. | It accepts base calls with associated quality scores assigned by Phred as input |
| B. | It is a free UNIX program |
| C. | It is for the assembly of whole-genome shotgun reads |
| D. | It doesn’t involve heuristic approach |
| Answer» E. | |
| 2. |
TIGR Assembler is a UNIX program from TIGR for assembly of large shotgun sequence fragments. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
Which of the following is incorrect about EULER? |
| A. | It is an assembly algorithm |
| B. | It uses a Eulerian Superpath approach, which is a polynomial algorithm |
| C. | In this approach, a sequence fragment is broken down to tuples of five nucleotides |
| D. | The tuples are distributed in a diagram with numerous nodes that are all interconnected |
| Answer» D. The tuples are distributed in a diagram with numerous nodes that are all interconnected | |
| 4. |
Which of the following is incorrect about Phrap? |
| A. | It aligns individual fragments in a pairwise fashion using the Smith–Waterman algorithm |
| B. | It doesn’t take input from Phred |
| C. | It is used for sequence assembly |
| D. | It is a UNIX program |
| Answer» C. It is used for sequence assembly | |
| 5. |
TIGR_ASSEMBLER_IS_A_UNIX_PROGRAM_FROM_TIGR_FOR_ASSEMBLY_OF_LARGE_SHOTGUN_SEQUENCE_FRAGMENTS.?$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 6. |
Which_of_the_following_is_incorrect_about_ARACHNE?$ |
| A. | It accepts base calls with associated quality scores assigned by Phred as input |
| B. | It is a free UNIX program |
| C. | It is for the assembly of whole-genome shotgun reads |
| D. | It doesn’t involve heuristic approach |
| Answer» E. | |
| 7. |
VecScreen is a primarily aimed for sequence assembly. |
| A. | True |
| B. | False |
| Answer» C. | |
| 8. |
Which of the following is incorrect about Phred? |
| A. | It is a UNIX program |
| B. | It doesn’t give a probability score in output |
| C. | It is used for base calling |
| D. | It uses a Fourier analysis to resolve fluorescence traces and predict actual peak locations of bases |
| Answer» C. It is used for base calling | |
| 9. |
Which of the following is untrue about base calling and assembly programs? |
| A. | The first step toward genome assembly includes derive base calls |
| B. | The first step toward genome assembly includes assigning associated quality scores |
| C. | One of the steps is to assemble the sequence reads into contiguous sequences |
| D. | There is no identifying overlap between sequence fragments |
| Answer» E. | |
| 10. |
When a sequence is generated from ____ ends of a single clone, the distance between the two opposing fragments of a clone is fixed to ________ meaning that they are always separated by a distance defined by a _____ length (normally 1,000 to 9,000 bases). |
| A. | both, an uncertain range, clone |
| B. | one, an uncertain range, clone |
| C. | both, a certain range, clone |
| D. | both, a certain range, gene |
| Answer» D. both, a certain range, gene | |
| 11. |
The major challenges in genome assembly are sequence errors, contamination by bacterial vectors, and repetitive sequence regions. |
| A. | True |
| B. | False |
| Answer» B. False | |