Explore topic-wise MCQs in Bioinformatics.

This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

Which of the following is untrue about DCA?

A. It stands for Divide-and-Conquer Alignment
B. It works by breaking each of the sequences into two smaller sections
C. The breaking points during the process are determined based on regional similarity of the sequences
D. If the sections are not short enough, further divisions are restricted as well
Answer» E.
Discussion
2.

As the amount of computational time and memory space required increases exponentially with the number of sequences, it makes the multidimensional search matrix method computationally prohibitive to use for a large data set.

A. True
B. False
Answer» B. False
Discussion
3.

In a multidimensional search matrix, for aligning N sequences, an (N+2)-dimensional matrix is needed to be filled with alignment scores.

A. True
B. False
Answer» C.
Discussion
4.

WHICH_OF_THE_FOLLOWING_IS_UNTRUE_ABOUT_DCA??$

A. It stands for Divide-and-Conquer Alignment
B. It works by breaking each of the sequences into two smaller sections
C. The breaking points during the process are determined based on regional similarity of the sequences
D. If the sections are not short enough, further divisions are restricted as well
Answer» E.
Discussion
5.

As the amount of computational time and memory space required increases exponentially with the number of sequences, it makes the multidimensional search matrix method computationally prohibitive to use for a large data set?

A. True
B. False
Answer» B. False
Discussion
6.

In a multidimensional search matrix, for aligning N sequences, an (N+2)-dimensional matrix is needed to be filled with alignment scores?

A. True
B. False
Answer» C.
Discussion
7.

There are two approaches viz. exhaustive and heuristic approaches used in multiple sequence alignment.

A. True
B. False
Answer» B. False
Discussion
8.

Given a multiple alignment of three sequences, the sum of scores is calculated as the sum of the dissimilarity scores of every pair of sequences at each position.

A. True
B. False
Answer» C.
Discussion
9.

Which of the following scores are not considered while calculating the SP scores?

A. All possible pair wise matches
B. All possible mismatches
C. All possible gap costs
D. Number of gap penalties
Answer» E.
Discussion
10.

The scoring function for multiple sequence alignment is based on the concept of sum of pairs (SP).

A. True
B. False
Answer» B. False
Discussion
11.

Which of the following cannot be related to multiple sequence alignment?

A. Many conserved and functionally critical amino acid residues can be identified in a protein multiple alignment
B. Multiple sequence alignment is also an essential prerequisite to carrying out phylogenetic analysis of sequence families and prediction of protein secondary and tertiary structures
C. Multiple sequence alignment also has applications in designing degenerate polymerase chain reaction (PCR) primers based on multiple related sequences
D. This method does not contribute much to degenerate polymerase chain reaction (PCR) primers creation
Answer» E.
Discussion
12.

There is a unique advantage of multiple sequence alignment because it reveals more biological information than many pair wise alignments can.

A. True
B. False
Answer» B. False
Discussion
13.

Related sequences are identified through the database similarity searching and as the process generates multiple matching sequence pairs, it is often necessary to convert the numerous pair wise alignments into a single alignment.

A. True
B. False
Answer» B. False
Discussion