MCQOPTIONS
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MCQOPTIONS
This section includes 94 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In case of acquired immune system, a secondary immune response is generated by the ______________ |
| A. | memory B-cells |
| B. | germ cells |
| C. | lymphoid tissues |
| D. | antigens |
| Answer» B. germ cells | |
| 2. |
T-cells secrete antibodies for eradicating the infected cells. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 3. |
Cytotoxic T cells are _____________ |
| A. | CD2⁺ |
| B. | CD4⁺ |
| C. | CD6⁺ |
| D. | CD8⁺ |
| Answer» E. | |
| 4. |
Humoral immunity is mediated by ______________ |
| A. | mast cells |
| B. | neutrophils |
| C. | lymphocytes |
| D. | leukocytes |
| Answer» D. leukocytes | |
| 5. |
Patients suffering from which of the following disease contain large quantities of a single type of antibodies? |
| A. | glioblastoma |
| B. | prostate cancer |
| C. | breast cancer |
| D. | multiple myeloma |
| Answer» E. | |
| 6. |
After entering the target cells, the granzymes activate the ______________________ |
| A. | antibodies |
| B. | chemokines |
| C. | perforins |
| D. | caspases |
| Answer» E. | |
| 7. |
B-cells arise from ______________________ |
| A. | progenitor cells |
| B. | antigens |
| C. | antibodies |
| D. | natural killer cells |
| Answer» B. antigens | |
| 8. |
The heavy and light chains of the antibodies are linked to one another by ____________________ |
| A. | covalent bonds |
| B. | disulfide bonds |
| C. | ionic bonds |
| D. | hydrogen bonds |
| Answer» C. ionic bonds | |
| 9. |
Each T-cell has a single species of T-cell receptor. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 10. |
Which antibody is produced at high levels in response to parasitic functions? |
| A. | IgA |
| B. | IgE |
| C. | IgG |
| D. | IgD |
| Answer» C. IgG | |
| 11. |
Who proposed the clonal selection theory? |
| A. | James Watson |
| B. | Niels Jerne |
| C. | Francis Crick |
| D. | Frank MacFarlane Burnet |
| Answer» E. | |
| 12. |
In all the immunoglobulins, there are _____ type(s) of light chains and ______ type(s) of heavy chain. |
| A. | 2, 1 |
| B. | 2, 2 |
| C. | 1, 2 |
| D. | 1, 1 |
| Answer» C. 1, 2 | |
| 13. |
For the body to develop immunologic tolerance, production of ____________________ must be prevented. |
| A. | antibodies |
| B. | antigens |
| C. | autoantibodies |
| D. | lymphocytes |
| Answer» D. lymphocytes | |
| 14. |
Adoptive immunotherapy involves the person’s own immune system for treatment against cancer. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 15. |
The drug Vectibix is directed against _____________________ |
| A. | Her2 receptor |
| B. | Her3 receptor |
| C. | EGF receptor |
| D. | EGF |
| Answer» D. EGF | |
| 16. |
Spontaneous remissions were studied by which of the following scientists? |
| A. | Barbara McClintock |
| B. | William Coley |
| C. | Fredrick Sanger |
| D. | James Watson |
| Answer» C. Fredrick Sanger | |
| 17. |
Conventional therapies like chemosurgery kill a large number of healthy cells in addition to cancer cells. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 18. |
p53 is capable of binding to which family of proteins? |
| A. | Bcl-1 |
| B. | Bcl-2 |
| C. | Bcl-3 |
| D. | Bcl-4 |
| Answer» C. Bcl-3 | |
| 19. |
p53 is a _________ |
| A. | translation factor |
| B. | polymerase |
| C. | endonuclease |
| D. | transcription factor |
| Answer» E. | |
| 20. |
Which immune cells are generally used in the treatment of cancer using adoptive immunotherapy? |
| A. | Mast cells |
| B. | Dendritic cells |
| C. | Neuronal cells |
| D. | Malignant cells |
| Answer» C. Neuronal cells | |
| 21. |
Angiogenesis is the process of formation of __________________ |
| A. | cancer cells |
| B. | blood vessels |
| C. | tissues |
| D. | immune cells |
| Answer» C. tissues | |
| 22. |
Cancer cells promote angiogenesis by secreting ________________________ |
| A. | antigens |
| B. | antibodies |
| C. | growth factors |
| D. | necrosis factors |
| Answer» D. necrosis factors | |
| 23. |
Which of the following disease is caused by a chromosomal translocation? |
| A. | Chronic myelogenous leukemia |
| B. | Hodgkin’s B-cell lymphoma |
| C. | Alzheimer’s disease |
| D. | Parkinson’s disease |
| Answer» B. Hodgkin’s B-cell lymphoma | |
| 24. |
Certain agents may be converted to mutagenic compounds by the action of cellular enzymes. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 25. |
Cyclooxygenase-2 synthesizes _____________________ |
| A. | sucrose |
| B. | prostaglandins |
| C. | steroids |
| D. | gametes |
| Answer» C. steroids | |
| 26. |
The immortality exhibited by the cancer cells is due to presence of _____________________ |
| A. | telomerase |
| B. | nuclease |
| C. | kinase |
| D. | protease |
| Answer» B. nuclease | |
| 27. |
When was the genetic basis of retinoblastoma first explained? |
| A. | 1961 |
| B. | 1971 |
| C. | 1981 |
| D. | 1991 |
| Answer» C. 1981 | |
| 28. |
The first tumor-suppressor gene to be studied is associated with ______________________ |
| A. | myeloma |
| B. | sarcoma |
| C. | retinoblastoma |
| D. | carcinoma |
| Answer» D. carcinoma | |
| 29. |
Oncogenes promote the growth of cancer cells. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 30. |
Which of the following is a test for detecting precancerous cells? |
| A. | MRI |
| B. | CT Scan |
| C. | Pap smear |
| D. | Endoscopy |
| Answer» D. Endoscopy | |
| 31. |
The expression of telomerase on cancer cells can be considered an epigenetic change. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 32. |
Cancer is monoclonal. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 33. |
Perforins and granzymes are secreted by ______________________ |
| A. | Cytotoxic T lymphocytes |
| B. | Helper T lymphocytes |
| C. | Regulatory T lymphocytes |
| D. | B lymphocytes |
| Answer» B. Helper T lymphocytes | |
| 34. |
Binding of which of the following antibody’s heavy chain initiates the lysis of bound bacterial cells? |
| A. | IgM |
| B. | IgD |
| C. | IgA |
| D. | IgE |
| Answer» B. IgD | |
| 35. |
Chemokines act as ___________________ |
| A. | buffers |
| B. | receptors |
| C. | chemoattractants |
| D. | antibodies |
| Answer» D. antibodies | |
| 36. |
The oncogenes act __________________ |
| A. | dominantly |
| B. | recessively |
| C. | occasionally |
| D. | frequently |
| Answer» B. recessively | |
| 37. |
The phagocytes can recognize pathogens by means of _____________________ |
| A. | necrosis factor |
| B. | complement activation |
| C. | pattern recognition receptors |
| D. | adhesion molecules |
| Answer» D. adhesion molecules | |
| 38. |
Which of the following is a humanized antibody? |
| A. | Doxorubicin |
| B. | Sulforaphane |
| C. | Vimentin |
| D. | Herceptin |
| Answer» E. | |
| 39. |
IgG is the predominant antibody in the secretion of respiratory tract. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 40. |
Which of the following is an essential requirement for the differentiation of regulatory T cells? |
| A. | FOXP1 |
| B. | FOXP2 |
| C. | FOXP3 |
| D. | FOXP4 |
| Answer» D. FOXP4 | |
| 41. |
The cancer cells are protected from ___________________ |
| A. | transcription |
| B. | mutation |
| C. | apoptosis |
| D. | contamination |
| Answer» D. contamination | |
| 42. |
Leukemias usually arise from _________ |
| A. | epithelial cells |
| B. | neurons |
| C. | blood-forming tissues |
| D. | epidermal cells |
| Answer» D. epidermal cells | |
| 43. |
The most common solid tumors – breast, colon etc. arise in _____________ cells. |
| A. | epithelial |
| B. | mesothelial |
| C. | nerve cells |
| D. | muscle cells |
| Answer» B. mesothelial | |
| 44. |
Plasma cells possess extensive smooth endoplasmic reticulum. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 45. |
Innate immune responses are accompanied by inflammation. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 46. |
Which type of interferons is associated with an antiviral innate response? |
| A. | Type I |
| B. | Type II |
| C. | Type III |
| D. | Type IV |
| Answer» B. Type II | |
| 47. |
Which type of immune cells are responsible for eradicating intracellular pathogens? |
| A. | natural killer cells |
| B. | mast cells |
| C. | neurons |
| D. | specific lymphocytes |
| Answer» B. mast cells | |
| 48. |
Which of the following is a stomach-dwelling bacterium? |
| A. | Helicobacter pylori |
| B. | Staphylococcus epidermis |
| C. | Staphylococcus hominis |
| D. | Pityrosporum |
| Answer» B. Staphylococcus epidermis | |
| 49. |
Which is the first antibody secreted by B cells following stimulation by an antigen? |
| A. | IgG |
| B. | IgM |
| C. | IgE |
| D. | IgD |
| Answer» C. IgE | |
| 50. |
Who discovered the vaccination against smallpox? |
| A. | Louis Pasteur |
| B. | Francis Crick |
| C. | Barbara McClintock |
| D. | Edward Jenner |
| Answer» E. | |