MCQOPTIONS
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This section includes 107 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The “Sliding filament model of muscle contraction” was proposed in the year ____________ |
| A. | 1954 |
| B. | 1964 |
| C. | 1974 |
| D. | 1984 |
| Answer» B. 1964 | |
| 2. |
Which type of cytoskeletal elements are involved in nonmuscle motility? |
| A. | microfilaments |
| B. | flagella |
| C. | intermediate filaments |
| D. | microtubules |
| Answer» B. flagella | |
| 3. |
Myosin I was discovered in the year _________ |
| A. | 1963 |
| B. | 1973 |
| C. | 1983 |
| D. | 1993 |
| Answer» C. 1983 | |
| 4. |
After incorporation into growing actin filaments, the associated ATP is _____________ |
| A. | degraded |
| B. | lysed |
| C. | hydrolyzed |
| D. | esterified |
| Answer» D. esterified | |
| 5. |
When was the first experimental evidence provided for axonal outgrowth and motility? |
| A. | 1907 |
| B. | 1807 |
| C. | 1847 |
| D. | 1947 |
| Answer» B. 1807 | |
| 6. |
Which of the following are used to study cell locomotion in fish? |
| A. | myoblasts |
| B. | oocytes |
| C. | spermatocytes |
| D. | keratocytes |
| Answer» E. | |
| 7. |
Fluorescently labeled _________ can reveal the attachment sites of fibroblasts on substratum. |
| A. | cofilin |
| B. | flagella |
| C. | vinculin |
| D. | microtubules |
| Answer» D. microtubules | |
| 8. |
Neurofilaments are the type _____ intermediate filaments. |
| A. | I |
| B. | II |
| C. | III |
| D. | IV |
| Answer» E. | |
| 9. |
Filamin is an example of ___________ proteins. |
| A. | capping |
| B. | depolymerization |
| C. | motor |
| D. | cross-linking |
| Answer» E. | |
| 10. |
The faster growing end of the microfilament is the plus-end. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 11. |
All skeletal muscles operate by _______________ |
| A. | shortening |
| B. | exciting |
| C. | firing |
| D. | contracting |
| Answer» B. exciting | |
| 12. |
The head of the myosin binds the ___________ |
| A. | ATP |
| B. | ADP |
| C. | Actin filament |
| D. | Neurofilament |
| Answer» D. Neurofilament | |
| 13. |
For cellular transport, plant cells rely on microfilaments. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 14. |
Which of the following prevents sacromeres from pulling apart during muscle stretching? |
| A. | titin |
| B. | vimentin |
| C. | myosin |
| D. | actin |
| Answer» B. vimentin | |
| 15. |
Microfilaments are mostly involved in _______________ processes. |
| A. | activation |
| B. | stimulation |
| C. | degradation |
| D. | motile |
| Answer» E. | |
| 16. |
Type II myosins are found primarily in __________ |
| A. | plant cells |
| B. | muscle cells |
| C. | nerve cells |
| D. | liver hepatocytes |
| Answer» C. nerve cells | |
| 17. |
Muscle cells are formed from the fusion of ___________ |
| A. | myoblasts |
| B. | fibroblasts |
| C. | mast cells |
| D. | neurons |
| Answer» B. fibroblasts | |
| 18. |
Which of the following binds to G-actin? |
| A. | thymosin |
| B. | lysin |
| C. | kinesin |
| D. | chymosin |
| Answer» B. lysin | |
| 19. |
‘Epidermolysis bullosa simplex’ is caused by the deficiency of ____________ polypeptide. |
| A. | myosin |
| B. | keratin |
| C. | kinesin |
| D. | niacin |
| Answer» C. kinesin | |
| 20. |
Nucleation is the slowest step in actin filament formation. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 21. |
Vimentin is a ___________ |
| A. | intermediate filament |
| B. | inherited disorder |
| C. | neurodegenerative disease |
| D. | microfilament |
| Answer» B. inherited disorder | |
| 22. |
Microfilaments are composed of globular subunits of _____________ |
| A. | myosin |
| B. | kinesin |
| C. | actin |
| D. | colchicine |
| Answer» D. colchicine | |
| 23. |
Cortex (of a cell) is located beneath the _____________ |
| A. | nucleus |
| B. | mitochondria |
| C. | ribosomes |
| D. | plasma membrane |
| Answer» E. | |
| 24. |
Which of the following can fragment actin filaments? |
| A. | profilin |
| B. | thymosin |
| C. | cofilin |
| D. | vimentin |
| Answer» D. vimentin | |
| 25. |
An organism in which cell motility takes place solely as a result of actin polymerization is ____________________ |
| A. | E. coli |
| B. | Corynebacterium |
| C. | Listeria monocytogenes |
| D. | Clostridium botulinum |
| Answer» D. Clostridium botulinum | |
| 26. |
Muscle cells are ___________ |
| A. | irregularly shaped |
| B. | cylindrically shaped |
| C. | extremely fragile |
| D. | extremely labile |
| Answer» C. extremely fragile | |
| 27. |
The drug cytochalasin blocks the _____________ |
| A. | ATP |
| B. | Microfilaments |
| C. | Plus-end of microfilaments |
| D. | Minus-end of microfilaments |
| Answer» D. Minus-end of microfilaments | |
| 28. |
Tropomodulin is a ___________ |
| A. | monomer-sequestering protein |
| B. | capping protein |
| C. | monomer unit |
| D. | motor protein |
| Answer» C. monomer unit | |
| 29. |
The drug cytochalasin blocks the _____________Latrunculin blocks the ____________ |
| A. | ATPplus-end of microfilaments |
| B. | Microfilamentsminus-end of microfilaments |
| C. | Plus-end of microfilamentsactin monomers |
| D. | Minus-end of microfilamentsactin filaments |
| Answer» D. Minus-end of microfilamentsactin filaments | |
| 30. |
Myosin II filaments display a transient construction in ______________ |
| A. | nonmuscle cells |
| B. | muscle cells |
| C. | actin filaments |
| D. | tubulin filaments |
| Answer» B. muscle cells | |
| 31. |
Lamellipodium is a protrusion of ________________ |
| A. | actin filaments |
| B. | fibroblasts |
| C. | myoblasts |
| D. | neurons |
| Answer» B. fibroblasts | |
| 32. |
Which type of myosins move toward the minus-end of a microfilament? |
| A. | myosin I |
| B. | myosin II |
| C. | myosin IV |
| D. | myosin VI |
| Answer» E. | |
| 33. |
Each tropomyosin is associated with _______ subunits of actin subunits. |
| A. | 2 |
| B. | 3 |
| C. | 7 |
| D. | 9 |
| Answer» D. 9 | |
| 34. |
In an axon, microtubules are oriented with their __________________ facing the cell body. |
| A. | plus end |
| B. | minus end |
| C. | vertical axis |
| D. | periphery |
| Answer» C. vertical axis | |
| 35. |
Kinesins are plus end-directed microtubular proteins. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 36. |
Which protein moves towards the minus end of the microtubule track? |
| A. | Nac |
| B. | ARF |
| C. | Sar1 |
| D. | Ncd |
| Answer» E. | |
| 37. |
Which of the following family of kinesins is incapable of movement along the microtubules? |
| A. | kinesin-1 |
| B. | kinesin-3 |
| C. | kinesin-13 |
| D. | kinesin-14 |
| Answer» D. kinesin-14 | |
| 38. |
Which microtubule-associated motor protein is responsible for the movement of cilia? |
| A. | kinesin |
| B. | niacin |
| C. | myosin |
| D. | dynein |
| Answer» E. | |
| 39. |
Crawling of cells over a substratum is an example of _________________ |
| A. | chemotraction |
| B. | neurodegenration |
| C. | nonmuscle motility |
| D. | muscular motility |
| Answer» D. muscular motility | |
| 40. |
Plectins are _____________ |
| A. | filaments |
| B. | proteins |
| C. | peripheral organelles |
| D. | fibres |
| Answer» C. peripheral organelles | |
| 41. |
Microtubules of cilia are stable. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 42. |
Cilia and flagella are the same structure. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 43. |
Non-motile cilia are called _________________ |
| A. | primary cilium |
| B. | cytochrome |
| C. | microfilaments |
| D. | microtubules |
| Answer» B. cytochrome | |
| 44. |
The core of the cilium is called ________________ |
| A. | flagellum |
| B. | primary cilium |
| C. | tubulin |
| D. | axoneme |
| Answer» E. | |
| 45. |
Bardet-Biedl syndrome (BBS) is caused due to mutations in genes that affect the assembly of _____________ |
| A. | mitochondria |
| B. | microfilaments |
| C. | cilia |
| D. | flagella |
| Answer» D. flagella | |
| 46. |
How many types of polypeptides are found in intermediate filaments? |
| A. | 2 |
| B. | 5 |
| C. | 10 |
| D. | 12 |
| Answer» C. 10 | |
| 47. |
The cytoskeleton framework plays a role in positioning of the cell organelles. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 48. |
Which of the following is found in the nucleus of animal cells? |
| A. | microtubules |
| B. | actin filaments |
| C. | microfilaments |
| D. | intermediate filaments |
| Answer» E. | |
| 49. |
Which protein is used for the fluorescent labeling of cytoskeleton elements of the cell? |
| A. | horseradish peroxide |
| B. | methylene blue |
| C. | bromophenol blue |
| D. | green fluorescent protein |
| Answer» E. | |
| 50. |
Atomic force microscopy uses _____________ |
| A. | X-rays |
| B. | Infrared light |
| C. | Nanosized tip |
| D. | Nickel tip |
| Answer» D. Nickel tip | |