MCQOPTIONS
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MCQOPTIONS
This section includes 105 Mcqs, each offering curated multiple-choice questions to sharpen your Cell Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Eough endoplasmic reticulum imports its proteins posttranslationally. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 2. |
Which of the following are phagocytic cells? |
| A. | neutrophils, macrophages |
| B. | neutrophils, mast cells |
| C. | mast cells, macrophages |
| D. | mast cells, antibodies |
| Answer» B. neutrophils, mast cells | |
| 3. |
Transformation from an early to a late endosome is characterized by a decrease in ______________ |
| A. | mobility |
| B. | lipid content |
| C. | pH |
| D. | protein content |
| Answer» D. protein content | |
| 4. |
Receptor–mediated endocytosis (RME) leads to the formation of ___________ coated pits. |
| A. | clathrin |
| B. | lipid |
| C. | lysosome |
| D. | mannose |
| Answer» B. lipid | |
| 5. |
‘Niemann–Pick type C disease’ is caused due to deficiency of a specific ________________ |
| A. | protein |
| B. | receptor |
| C. | ligand |
| D. | gene |
| Answer» B. receptor | |
| 6. |
Which of the following is a type of endocytosis? |
| A. | Pinocytosis |
| B. | Phagocytosis |
| C. | Hemolysis |
| D. | Cytogenesis |
| Answer» B. Phagocytosis | |
| 7. |
Destruction and replacement of cell’s own organelles is called ____________ |
| A. | transition |
| B. | turnover |
| C. | endocytosis |
| D. | exocytosis |
| Answer» C. endocytosis | |
| 8. |
t-SNAREs are present on the _____________________ |
| A. | budding vesicle |
| B. | transportation material |
| C. | target compartment |
| D. | tethering proteins |
| Answer» D. tethering proteins | |
| 9. |
For which of the following organelles, the proteins to be imported remain in their native folded state? |
| A. | Peroxisomes |
| B. | Mitochondrion |
| C. | Chloroplast |
| D. | Endoplasmic reticulum |
| Answer» B. Mitochondrion | |
| 10. |
Mycobacterium tuberculosis inhibits the fusion of its phagosome with _________________ following phagocytosis. |
| A. | membrane |
| B. | lysosome |
| C. | endosome |
| D. | chromosome |
| Answer» C. endosome | |
| 11. |
Clathrin present on the clathrin-coated vesicles is a ______________ |
| A. | carbohydrate |
| B. | protein |
| C. | oligosaccharide |
| D. | enzyme |
| Answer» C. oligosaccharide | |
| 12. |
Most of the proteins of mitochondria are synthesized in the ______________ |
| A. | mitochondrial matrix |
| B. | mitochondrial membrane |
| C. | cytosol |
| D. | medial cisternae |
| Answer» D. medial cisternae | |
| 13. |
The protein coated vesicle must release its components into the Cytosol before fusing with the target site. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 14. |
Lipofuscin granules decrease in number as individual grows older. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 15. |
Synaptobrevin is a ______________ |
| A. | membrane vesicle |
| B. | lipid anchor |
| C. | t-SNARE |
| D. | v-SNARE |
| Answer» E. | |
| 16. |
The enzyme N-acetylglucosamine phosphotransferase is responsible for ____________ |
| A. | mannose phosphorylation |
| B. | sucrose phosphorylation |
| C. | tethering Golgi stack |
| D. | modification of integral proteins |
| Answer» B. sucrose phosphorylation | |
| 17. |
90% of the volume of a plant cell is occupied by the vacuole. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 18. |
A molecule of clathrin has a ______________ structure. |
| A. | triskelion |
| B. | spherical |
| C. | cylindrical |
| D. | polygonal |
| Answer» B. spherical | |
| 19. |
Which of the following biomolecules are not synthesized by the endoplasmic reticulum? |
| A. | Proteins |
| B. | Lipids |
| C. | Nucleic acids |
| D. | Cholesterol |
| Answer» D. Cholesterol | |
| 20. |
Which type of signals direct the proteins to their appropriate cellular destinations? |
| A. | sorting signals |
| B. | apoptotic signals |
| C. | ubiquitylation |
| D. | degradation signals |
| Answer» B. apoptotic signals | |
| 21. |
Following internalization, vesicle–bound materials are transported to _________________ |
| A. | nucleus |
| B. | peroxisomes |
| C. | lysosomes |
| D. | endosomes |
| Answer» E. | |
| 22. |
Green fluorescent protein (GFP) is observed from which of the following organism? |
| A. | Octopus |
| B. | Jellyfish |
| C. | Drosophila |
| D. | Mouse |
| Answer» C. Drosophila | |
| 23. |
“Pulse-chase” is an experiment related to radioactivity. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 24. |
The microsomal content of a ruptured cell represents how many organelles? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» C. 3 | |
| 25. |
Which of the following technique was used to study the function of ribosomes and contrast it with the function of ER membrane? |
| A. | Cell-free systems |
| B. | Autoradiography |
| C. | Spectroscopy |
| D. | Microscopy |
| Answer» B. Autoradiography | |
| 26. |
After the synthesis of proteins in endoplasmic reticulum, where do they reach before being secreted from the cell? |
| A. | Lysosomes |
| B. | Golgi complex |
| C. | Lysozymes |
| D. | Nucleus |
| Answer» C. Lysozymes | |
| 27. |
The membranes of rough endoplasmic reticulum (RER) and smooth endoplasmic reticulum (SER) are continuous. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 28. |
Tonoplast is a ___________ |
| A. | membrane |
| B. | toxic compound |
| C. | sphingolipid |
| D. | glycoprotein |
| Answer» B. toxic compound | |
| 29. |
In autophagy, the organelle’s to be ingested are covered by a ______________ |
| A. | protein coat |
| B. | oligosaccharides |
| C. | double membrane |
| D. | single membrane |
| Answer» D. single membrane | |
| 30. |
Retrieval signals, present on the C-terminus of ER resident proteins are captured by the receptors present on __________________ |
| A. | Clathrin-coated vesicles |
| B. | Golgi complex |
| C. | COPI-coated vesicles |
| D. | COPII-coated vesicles |
| Answer» D. COPII-coated vesicles | |
| 31. |
Water enters the vacuole by ____________ |
| A. | reverse osmosis |
| B. | osmosis |
| C. | active diffusion |
| D. | passive diffusion |
| Answer» C. active diffusion | |
| 32. |
Receptor down regulation leads to a decrease in the sensitivity of the cell towards further stimulation. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 33. |
Glycosyltransferases are selected by CopII-coat proteins. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 34. |
Where is the proton pump located in a lysosome? |
| A. | cytosol |
| B. | membrane |
| C. | attached with enzymes |
| D. | extracellularly connected |
| Answer» C. attached with enzymes | |
| 35. |
Subcellular fragmentation is a technique to study the endomembrane system, based on _____________ of the cells. |
| A. | homogenization |
| B. | degradation |
| C. | labeling |
| D. | freezing |
| Answer» B. degradation | |
| 36. |
Which type of molecules are used for labeling the cellular entities in the autoradiography technique? |
| A. | Glycoproteins |
| B. | Radioisotopes |
| C. | Stereoisomers |
| D. | Enantiomers |
| Answer» C. Stereoisomers | |
| 37. |
Which of the following is a toxic by-product stored in the plant cell vacuole that is clinical importance? |
| A. | oxytocin |
| B. | sialic acid |
| C. | digitalis |
| D. | tonoplast |
| Answer» D. tonoplast | |
| 38. |
Plant vacuoles are also sites of intracellular digestion. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 39. |
Sar1 is a _______ |
| A. | carbohydrate |
| B. | glycolipid |
| C. | G-protein |
| D. | alkali |
| Answer» D. alkali | |
| 40. |
Gaucher disease is caused due to deficiency of ______________ |
| A. | hexosaminidase A |
| B. | lysosomes |
| C. | glucocerebrosidase |
| D. | mannose phophate |
| Answer» D. mannose phophate | |
| 41. |
The main function of lysosomes is ____________ |
| A. | excretion |
| B. | synthesis |
| C. | mobility |
| D. | digestion |
| Answer» E. | |
| 42. |
A mutant organism or cell encodes normal proteins that can be used for studying the endomembrane system. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» C. May be True or False | |
| 43. |
In the ‘I-cell disease’, lysosomes are ___________ |
| A. | absent |
| B. | bloated |
| C. | short-lived |
| D. | immobile |
| Answer» C. short-lived | |
| 44. |
When a cell is in nutrient deprived state, autophagy increases. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 45. |
The process in which cell uptakes extracellular material bound to cell surface receptors is known as __________________ |
| A. | phagocytosis |
| B. | pinocytosis |
| C. | receptor–mediated endocytosis |
| D. | bulk–phase endocytosis |
| Answer» D. bulk–phase endocytosis | |
| 46. |
Lysosomal storage disorders are caused due to ______________ |
| A. | absence of lysosomes |
| B. | absence of a single lysosome |
| C. | absence of integral membrane proteins |
| D. | accumulation of lipofuschin granules |
| Answer» C. absence of integral membrane proteins | |
| 47. |
In plant cells, by-products of the metabolic pathways are stored in _____________ |
| A. | vacuole |
| B. | mitochondrion |
| C. | chloroplast |
| D. | nucleus |
| Answer» B. mitochondrion | |
| 48. |
Which of the following biomolecules are contained in the lysosomes? |
| A. | nucleic acids |
| B. | ribonucleic acids |
| C. | proteins |
| D. | polysaccharides |
| Answer» D. polysaccharides | |
| 49. |
Which adaptor molecule operate in clathrin–mediated endocytosis? |
| A. | GGA |
| B. | AP1 |
| C. | AP2 |
| D. | Sar1 |
| Answer» D. Sar1 | |
| 50. |
Which state of the ‘Rabs’ is the active state? |
| A. | GDP-bound |
| B. | GTP-bound |
| C. | Membrane-bound |
| D. | Lipid-bound |
| Answer» C. Membrane-bound | |