MCQOPTIONS
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MCQOPTIONS
This section includes 7 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The all-against-all analyses provide an indication as to the number of protein/gene families in an organism. This number represents the core proteome of the organism from which all biological functions have diversified. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 2. |
Which of the given statements is incorrect about Clustering by single linkage? |
| A. | In First step, a group of related sequences found in the all-against-all proteome comparison is subjected to a multiple sequence alignment usually by CLUSTALW |
| B. | A neighbor-joining algorithm is rarely used in this method |
| C. | This procedure and the algorithms are the same as those used to make a phylogenetic tree by the distance methods |
| D. | A distance matrix that shows the number of amino acid changes between each pair of sequences is made |
| Answer» C. This procedure and the algorithms are the same as those used to make a phylogenetic tree by the distance methods | |
| 3. |
Which of the given statements is incorrect about Clustering by making subgraphs? |
| A. | Each sequence is a vertex and each pair of sequences that is matched with a significant alignment score is joined by an edge that is weighted according to the statistical significance of the alignment score |
| B. | One way to identify the most strongly supported clusters is simply to add the most weakly supported edges in the graph |
| C. | One way to identify the most strongly supported clusters is simply to remove the most weakly supported edges in the graph |
| D. | An edge is weighted according to the statistical significance of the alignment score |
| Answer» D. An edge is weighted according to the statistical significance of the alignment score | |
| 4. |
Which of the given statements is incorrect about Cluster analysis? |
| A. | Clustering organizes the proteins into groups by some objective criterion |
| B. | One criterion for a matching protein pair is the statistical significance of their alignment score |
| C. | The P or E value from BLAST searches cannot be the criterion for a matching protein pair |
| D. | A criterion for clustering proteins is the distance between each pair of sequences in a multiple sequence alignment |
| Answer» D. A criterion for clustering proteins is the distance between each pair of sequences in a multiple sequence alignment | |
| 5. |
Which of the given statements is incorrect about All-against-all Self-comparison? |
| A. | A comparison of each protein in the proteome with all other proteins distinguishes unique proteins from proteins that have arisen from gene duplication, and also reveals the number of protein families but the domain content of these proteins cannot be known |
| B. | In all-against-all proteome comparison, each protein is used as a query in a similarity search against the remaining proteome |
| C. | In all-against-all proteome comparison, the similar sequences are ranked by the quality and length of the alignments found |
| D. | In all-against-all proteome comparison, The search is conducted with each alignment score receiving a statistical evaluation (P or E valu |
| Answer» B. In all-against-all proteome comparison, each protein is used as a query in a similarity search against the remaining proteome | |
| 6. |
Which of the following information Sequence comparisons do not provide? |
| A. | Gene relationships |
| B. | Function history |
| C. | Evolutionary history |
| D. | Gene locations |
| Answer» E. | |
| 7. |
Comparative genomics includes a comparison of gene number, gene content, and gene location in both prokaryotic and eukaryotic groups of organisms. |
| A. | True |
| B. | False |
| Answer» B. False | |