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This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
Which of the following is incorrect the ‘word’ method? |
A. | Both BLAST and FASTA use a heuristic word method |
B. | Word method is used for fast pairwise sequence alignment in BLAST and FASTA |
C. | The basic assumption is that two related sequences must have at least one word in common |
D. | Two related sequences must have at zero word in common while assuming |
Answer» E. | |
2. |
Currently, there are two major heuristic algorithms for performing database searches: BLAST and FASTA. |
A. | True |
B. | False |
Answer» B. False | |
3. |
In heuristic methods, speed doesn’t vary with the size of database. |
A. | True |
B. | False |
Answer» C. | |
4. |
Sensitivity refers to the ability to find as many correct hits as possible. |
A. | True |
B. | False |
Answer» B. False | |
5. |
Which of the following is not one of the requirements for implementing algorithms for sequence database searching? |
A. | Size of the dataset |
B. | Sensitivity |
C. | Specificity |
D. | Speed |
Answer» B. Sensitivity | |
6. |
The main application of pairwise alignment is retrieving biological sequences in databases based on similarity. |
A. | True |
B. | False |
Answer» B. False | |
7. |
WHICH_OF_THE_FOLLOWING_IS_INCORRECT_THE_‚ÄÖ√Ñ√∂‚ÀÖ√Ë‚Àւ§WORD‚ÄÖ√Ñ√∂‚ÀÖ√Ë‚ÀÖ¬•_METHOD??$# |
A. | Both BLAST and FASTA use a heuristic word method |
B. | Word method is usedfor fast pairwise sequencealignment in BLAST and FASTA |
C. | The basic assumption is that two relatedsequences must have at least one word in common |
D. | Two related sequences must have at zero word in common while assuming |
Answer» E. | |
8. |
Currently, there are two major heuristic algorithms for performing databasesearches: BLAST and FASTA? |
A. | True |
B. | False |
Answer» B. False | |
9. |
An increase in sensitivity is associated with _______ in selectivity. |
A. | no specific change |
B. | increase |
C. | decrease |
D. | exponential increase |
Answer» D. exponential increase | |
10. |
In heuristic methods, speed doesn’t vary with the size of database.$ |
A. | True |
B. | False |
Answer» C. | |
11. |
The specificity refers to the ability to include incorrect hits. |
A. | True |
B. | False |
Answer» C. | |
12. |
Sensitivity refers to the ability to find as manycorrect hits as possible. |
A. | True |
B. | False |
Answer» B. False | |
13. |
Which of the following is not one of the requirements for implementing algorithms for sequence databasesearching? |
A. | Size of the dataset |
B. | Sensitivity |
C. | Specificity |
D. | Speed |
Answer» B. Sensitivity | |
14. |
Dynamic programming method is the fastest and most practical method. |
A. | True |
B. | False |
Answer» C. | |
15. |
A main application of pairwise alignment is retrieving biological sequences in databases based on similarity. |
A. | True |
B. | False |
Answer» B. False | |