Which of the given statement is incorrect about Clusters of functionally related genes?

• A. In microbial genomes, genes specifying a metabolic pathway may be contiguous on the genome where they are coregulated transcriptionally in an operon by a common promoter
• B. In related organisms, gene order on the chromosome is least likely to be conserved
• C. As the relationship between the organisms decreases, local groups of genes remain clustered together, but chromosomal rearrangements move the clusters to other locations
• D. The function of a particular gene can sometimes be predicted, given the known function of a neighboring, closely linked gene