1.

Which of the following is wrong statement about the maximum likelihood method’s steps?

A. It starts with an evolutionary model of sequence change that provides estimates of rates of substitution of one base for another
B. In the beginning there is an evolutionary model of sequence change that provides estimates of transitions and transversions in a set of nucleic acid sequences
C. The rates of all possible substitutions are chosen so that the base composition differs
D. The set of sequences is then aligned
Answer» D. The set of sequences is then aligned


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