Which of the following is untrue regarding Expectation Maximization algorithm?

• A. An initial guess is made as to the location and size of the site of interest in each of the sequences, and these parts of the sequence are aligned
• B. The alignment provides an estimate of the base or amino acid composition of each column in the site
• C. The column-by-column composition of the site already available is used to estimate the probability of finding the site at any position in each of the sequences
• D. The row-by-column composition of the site already available is used to estimate the probability