Which of the following is untrue about Electrostatic Complementarity?

• A. The electrostatic properties of biomolecules play an important role in determining interactions
• B. The burial of charged residues at protein-protein/DNA interfaces is thought to be generally net destabilizing with the hydrophobic effect being the primary driving force
• C. Charged groups involved in the biomolecular interface are often stabilized by other polar or oppositely charged groups on the interacting molecule
• D. Charged groups involved in the biomolecular interface are often stabilized by similar polar or same charged groups on the interacting molecule