IN_1971,_FIRST_ESTIMATION_OF_THE_ENERGY_ASSOCIATED_WITH_REGIONS_OF_SECONDARY_STRUCTURE_BY_EXTRAPOLATION_FROM_STUDIES_WITH_SMALL_MOLECULES_WAS_DONE_AND_THEN_ATTEMPT_WAS_MADE_TO_PREDICT_WHICH_CONFIGURATIONS_OF_LARGER_MOLECULES_WERE_THE_MOST_ENERGETICALLY_STABLE.?$

IN_1971,_FIRST_ESTIMATION_OF_THE_ENERGY_ASSOCIATED_WITH_REGIONS_OF_SEC

1.	IN_1971,_FIRST_ESTIMATION_OF_THE_ENERGY_ASSOCIATED_WITH_REGIONS_OF_SECONDARY_STRUCTURE_BY_EXTRAPOLATION_FROM_STUDIES_WITH_SMALL_MOLECULES_WAS_DONE_AND_THEN_ATTEMPT_WAS_MADE_TO_PREDICT_WHICH_CONFIGURATIONS_OF_LARGER_MOLECULES_WERE_THE_MOST_ENERGETICALLY_STABLE.?$
A.	True
B.	False
Answer» B. False

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Nussinov and Jacobson (1980) were the first to design a precise and efficient algorithm for predicting secondary structure.
In 1971, first estimation of the energy associated with regions of secondary structure by extrapolation from studies with small molecules was done and then an attempt was made to predict which configurations of larger molecules were the most energetically stable.
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IN_1971,_FIRST_ESTIMATION_OF_THE_ENERGY_ASSOCIATED_WITH_REGIONS_OF_SECONDARY_STRUCTURE_BY_EXTRAPOLATION_FROM_STUDIES_WITH_SMALL_MOLECULES_WAS_DONE_AND_THEN_ATTEMPT_WAS_MADE_TO_PREDICT_WHICH_CONFIGURATIONS_OF_LARGER_MOLECULES_WERE_THE_MOST_ENERGETICALLY_STABLE.?$
Nussinov_and_Jacobson_(1980)_were_the_first_to_design_a_precise_and_efficient_algorithm_for_predicting_secondary_structure.$
Martinez (1984) made a list of possible double-stranded regions, and these regions were then given weights in proportion to their equilibrium constants, calculated by _____?
The third assumption in predicting RNA secondary structure is that, the structure is assumed to be formed by _____ of the chain back on itself in a manner that ________

IN_1971,_FIRST_ESTIMATION_OF_THE_ENERGY_ASSOCIATED_WITH_REGIONS_OF_SECONDARY_STRUCTURE_BY_EXTRAPOLATION_FROM_STUDIES_WITH_SMALL_MOLECULES_WAS_DONE_AND_THEN_ATTEMPT_WAS_MADE_TO_PREDICT_WHICH_CONFIGURATIONS_OF_LARGER_MOLECULES_WERE_THE_MOST_ENERGETICALLY_STABLE.?$

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