WHICH_OF_THE_GIVEN_STATEMENT_IS_INCORRECT_ABOUT_FUNCTIONAL_GENOMICS??$

When two or more members of a gene family are found ,rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family

Functional genomics involves the preparation of mutant or transgenic organisms with a mutant form of a particular gene usually designed to prevent expression of the gene

An abnormal properties of the mutant organism does not reveal the gene function

When two or more members of a gene family are found ,rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family

A more detailed analysis of the relative amount of sequence variability in a chromosomal region within populations of closely related species can reveal the presence of genes that are under selection

Which_of_the_given_statement_is_incorrect_about_gene_map?$

Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next

Gene order in two related organisms reflects the order that was present in a common ancestor genome. Chromosomal breaks followed by a reassembly of fragments in a different order can produce new gene maps

Gene order is only revealed by the physical order of genes on the chromosome

Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next

These types of evolutionary changes in genomes have been modeled by computational methods

Which of the following information is not directly obtained by microarray analysis?

Genes that respond to a given environmental signal to the same extent

Which genes are expressed at a particular stage of the cell cycle

Which genes are expressed at a particular stage of developmental cycle of an organism

Which genes are depleted at what time

Genes that respond to a given environmental signal to the same extent

In case of genome sequence assembly which of the given statement is incorrect?

Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines

Full chromosomal sequences are assembled from the overlaps in a highly redundant set of fragments by an automatic computational method or from the fragment order on a physical map

Chromosome cloning is carried out in bacterial artifical chromosomes (BACs)

Chromosomes of a target organism are purified, fragmented, and subcloned in fragments of size hundreds of bp

Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines

9 + Mcqs in Sequence Assembly Gene Identification in Bioinformatics Page 1 McqOptions

1.	WHICH_OF_THE_GIVEN_STATEMENT_IS_INCORRECT_ABOUT_FUNCTIONAL_GENOMICS??$
A.	Functional genomics involves the preparation of mutant or transgenic organisms with a mutant form of a particular gene usually designed to prevent expression of the gene
B.	An abnormal properties of the mutant organism does not reveal the gene function
C.	When two or more members of a gene family are found ,rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family
D.	A more detailed analysis of the relative amount of sequence variability in a chromosomal region within populations of closely related species can reveal the presence of genes that are under selection
Answer» C. When two or more members of a gene family are found ,rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family

Discussion

2.	Which_of_the_given_statement_is_incorrect_about_gene_map?$
A.	Gene order in two related organisms reflects the order that was present in a common ancestor genome. Chromosomal breaks followed by a reassembly of fragments in a different order can produce new gene maps
B.	Gene order is only revealed by the physical order of genes on the chromosome
C.	Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next
D.	These types of evolutionary changes in genomes have been modeled by computational methods
Answer» C. Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next

Discussion

3.	Which of the following information is not directly obtained by microarray analysis?
A.	Which genes are expressed at a particular stage of the cell cycle
B.	Which genes are expressed at a particular stage of developmental cycle of an organism
C.	Which genes are depleted at what time
D.	Genes that respond to a given environmental signal to the same extent
Answer» D. Genes that respond to a given environmental signal to the same extent

Discussion

4.	Gene identification in prokaryotic organisms is simplified by their lacking _____
A.	exons
B.	introns
C.	coding segments
D.	useful nucleotide sequences
Answer» C. coding segments

Discussion

5.	TEs (transposable elements) can at most comprise one-fourth of the genome sequence.
A.	True
B.	False
Answer» C.

Discussion

6.	In case of genome sequence assembly which of the given statement is incorrect?
A.	Full chromosomal sequences are assembled from the overlaps in a highly redundant set of fragments by an automatic computational method or from the fragment order on a physical map
B.	Chromosome cloning is carried out in bacterial artifical chromosomes (BACs)
C.	Chromosomes of a target organism are purified, fragmented, and subcloned in fragments of size hundreds of bp
D.	Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines
Answer» D. Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines

Discussion

7.	Screening the predicted protein sequences against ______ library confirms the prediction and expression of the gene.
A.	expressed sequence tag (EST)
B.	tags
C.	palindromes
D.	proteomes
Answer» B. tags

Discussion

8.	Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism.
A.	True
B.	False
Answer» B. False

Discussion

9.	Sequencing of genomes depends on the assembly of a large number of DNA reads into a linear, contiguous DNA sequence.
A.	True
B.	False
Answer» B. False

Discussion

Explore topic-wise MCQs in Bioinformatics.

WHICH_OF_THE_GIVEN_STATEMENT_IS_INCORRECT_ABOUT_FUNCTIONAL_GENOMICS??$

Which_of_the_given_statement_is_incorrect_about_gene_map?$

Which of the following information is not directly obtained by microarray analysis?

Gene identification in prokaryotic organisms is simplified by their lacking _____

TEs (transposable elements) can at most comprise one-fourth of the genome sequence.

In case of genome sequence assembly which of the given statement is incorrect?

Screening the predicted protein sequences against ______ library confirms the prediction and expression of the gene.

Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism.

Sequencing of genomes depends on the assembly of a large number of DNA reads into a linear, contiguous DNA sequence.