MCQOPTIONS
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MCQOPTIONS
This section includes 9 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
WHICH_OF_THE_GIVEN_STATEMENT_IS_INCORRECT_ABOUT_FUNCTIONAL_GENOMICS??$ |
| A. | Functional genomics involves the preparation of mutant or transgenic organisms with a mutant form of a particular gene usually designed to prevent expression of the gene |
| B. | An abnormal properties of the mutant organism does not reveal the gene function |
| C. | When two or more members of a gene family are found ,rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family |
| D. | A more detailed analysis of the relative amount of sequence variability in a chromosomal region within populations of closely related species can reveal the presence of genes that are under selection |
| Answer» C. When two or more members of a gene family are found ,rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family | |
| 2. |
Which_of_the_given_statement_is_incorrect_about_gene_map?$ |
| A. | Gene order in two related organisms reflects the order that was present in a common ancestor genome. Chromosomal breaks followed by a reassembly of fragments in a different order can produce new gene maps |
| B. | Gene order is only revealed by the physical order of genes on the chromosome |
| C. | Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next |
| D. | These types of evolutionary changes in genomes have been modeled by computational methods |
| Answer» C. Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next | |
| 3. |
Which of the following information is not directly obtained by microarray analysis? |
| A. | Which genes are expressed at a particular stage of the cell cycle |
| B. | Which genes are expressed at a particular stage of developmental cycle of an organism |
| C. | Which genes are depleted at what time |
| D. | Genes that respond to a given environmental signal to the same extent |
| Answer» D. Genes that respond to a given environmental signal to the same extent | |
| 4. |
Gene identification in prokaryotic organisms is simplified by their lacking _____ |
| A. | exons |
| B. | introns |
| C. | coding segments |
| D. | useful nucleotide sequences |
| Answer» C. coding segments | |
| 5. |
TEs (transposable elements) can at most comprise one-fourth of the genome sequence. |
| A. | True |
| B. | False |
| Answer» C. | |
| 6. |
In case of genome sequence assembly which of the given statement is incorrect? |
| A. | Full chromosomal sequences are assembled from the overlaps in a highly redundant set of fragments by an automatic computational method or from the fragment order on a physical map |
| B. | Chromosome cloning is carried out in bacterial artifical chromosomes (BACs) |
| C. | Chromosomes of a target organism are purified, fragmented, and subcloned in fragments of size hundreds of bp |
| D. | Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines |
| Answer» D. Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines | |
| 7. |
Screening the predicted protein sequences against ______ library confirms the prediction and expression of the gene. |
| A. | expressed sequence tag (EST) |
| B. | tags |
| C. | palindromes |
| D. | proteomes |
| Answer» B. tags | |
| 8. |
Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 9. |
Sequencing of genomes depends on the assembly of a large number of DNA reads into a linear, contiguous DNA sequence. |
| A. | True |
| B. | False |
| Answer» B. False | |