MCQOPTIONS
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MCQOPTIONS
This section includes 9 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the given statement is incorrect about the gene map? |
| A. | Gene order in two related organisms reflects the order that was present in a common ancestor genome. Chromosomal breaks followed by reassembly of fragments in a different order can produce new gene maps |
| B. | Gene order is only revealed by the physical order of genes on the chromosome |
| C. | Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next |
| D. | a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the nextd) These types of evolutionary changes in genomes have been modeled by computational methods |
| Answer» C. Sequence variations (polymorphisms) that are close to (tightly linked) a trait may be used to trace the trait by virtue of the fact that the polymorphism and the trait are seldom separated from one generation to the next | |
| 2. |
Which of the given statement is incorrect about Functional Genomics? |
| A. | Functional genomics involves the preparation of mutant or transgenic organisms with a mutant form of a particular gene usually designed to prevent expression of the gene |
| B. | An abnormal properties of the mutant organism does not reveal the gene function |
| C. | When two or more members of a gene family are found, rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family |
| D. | A more detailed analysis of the relative amount of sequence variability in a chromosomal region within populations of closely related species can reveal the presence of genes that are under selection |
| Answer» C. When two or more members of a gene family are found, rather than a single match to a known gene, the biological activity of these members may be analyzed by functional genomics to look for diversification of function in the family | |
| 3. |
Which of the following information is not directly obtained by microarray analysis? |
| A. | Which genes are expressed at a particular stage of the cell cycle |
| B. | Which genes are expressed at a particular stage of developmental cycle of an organism |
| C. | Which genes are depleted at what time |
| D. | Genes that respond to a given environmental signal to the same extent |
| Answer» D. Genes that respond to a given environmental signal to the same extent | |
| 4. |
Gene identification in prokaryotic organisms is simplified by their lacking _________ |
| A. | exons |
| B. | introns |
| C. | coding segments |
| D. | useful nucleotide sequences |
| Answer» C. coding segments | |
| 5. |
TEs (Transposable Elements) can at most comprise one-fourth of the genome sequence. |
| A. | True |
| B. | False |
| Answer» C. | |
| 6. |
In case of genome sequence assembly which of the given statement is incorrect? |
| A. | Full chromosomal sequences are assembled from the overlaps in a highly redundant set of fragments by an automatic computational method or from the fragment order on a physical map |
| B. | Chromosome cloning is carried out in bacterial artifical chromosomes (BACs) |
| C. | Chromosomes of a target organism are purified, fragmented, and subcloned in fragments of size hundreds of bp |
| D. | Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines |
| Answer» D. Genome sequences are assembled from DNA sequence fragments of approximate length 500 bp obtained using DNA sequencing machines | |
| 7. |
Screening the predicted protein sequences against ______ library confirms the prediction and expression of the gene. |
| A. | expressed sequence tag (EST) |
| B. | tags |
| C. | palindromes |
| D. | proteomes |
| Answer» B. tags | |
| 8. |
Each genome sequence is scanned for protein-encoding genes using gene models trained on known gene sequences from the same organism. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 9. |
Sequencing of genomes depends on the assembly of a large number of DNA reads into a linear, contiguous DNA sequence. |
| A. | True |
| B. | False |
| Answer» B. False | |