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This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
CATH is a combination of manual curation and automated procedure, which makes the process less subjective. |
A. | True |
B. | False |
Answer» B. False | |
2. |
SCOP is _______ based on manual comparison of structures by human experts with no quantitative criteria to group proteins. |
A. | entirely |
B. | almost entirely |
C. | not |
D. | partially |
Answer» C. not | |
3. |
In CATH, Structural domain separation is carried by ___________ |
A. | manual comparison only |
B. | computer programs only |
C. | human expertise only |
D. | a combined effort of a human expert and computer programs |
Answer» E. | |
4. |
SCOP_IS_________BASED_ON_MANUAL_COMPARISON_OF_STRUCTURES_BY_HUMAN_EXPERTS_WITH_NO_QUANTITATIVE_CRITERIA_TO_GROUP_PROTEINS.?$ |
A. | entirely |
B. | almost entirely |
C. | not |
D. | partially |
Answer» C. not | |
5. |
CATH_is_a_combination_of_manual_curation_and_automated_procedure,_which_makes_the_process_less_subjective$ |
A. | True |
B. | False |
Answer» B. False | |
6. |
Which of the following is untrue about SCOP and CATH? |
A. | The definition for class in CATH is quite dissimilar to that in SCOP |
B. | The definition for class in CATH is based on secondary structure content |
C. | Architecture is a unique level in CATH, intermediate between fold and class |
D. | The definition for class in CATH is similar to that in SCOP |
Answer» E. | |
7. |
In CATH, Structural domain separation is carried by |
A. | manual comparison only |
B. | computer programs only |
C. | human expertise only |
D. | a combined effort of a human expert and computer programs |
Answer» E. | |
8. |
Members within the ____ fold ______ have evolutionary relationships. |
A. | same, always |
B. | same, do not always |
C. | one, always |
D. | different, do not |
Answer» C. one, always | |
9. |
Which of the following is untrue about SCOP? |
A. | It is a database for comparing and classifying protein structures |
B. | It is constructed almost entirely based on manual examination of protein structures |
C. | The proteins are grouped into hierarchies of classes, folds, superfamilies, and families |
D. | The SCOP families consist of proteins having low sequence identity (>30%) |
Answer» E. | |
10. |
The last step in structure classification involves grouping proteins/domains of similar structures. |
A. | True |
B. | False |
Answer» B. False | |
11. |
The second step in structure classification is to separate structurally distinct domains within a structure. |
A. | True |
B. | False |
Answer» B. False | |
12. |
The first step in structure classification is to remove redundancy from databases. |
A. | True |
B. | False |
Answer» B. False | |
13. |
The classification results from both systems, SCOP and CATH are quite dissimilar. |
A. | True |
B. | False |
Answer» C. | |