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This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
CATH is a combination of manual curation and automated procedure, which makes the process less subjective. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 2. |
SCOP is _______ based on manual comparison of structures by human experts with no quantitative criteria to group proteins. |
| A. | entirely |
| B. | almost entirely |
| C. | not |
| D. | partially |
| Answer» C. not | |
| 3. |
In CATH, Structural domain separation is carried by ___________ |
| A. | manual comparison only |
| B. | computer programs only |
| C. | human expertise only |
| D. | a combined effort of a human expert and computer programs |
| Answer» E. | |
| 4. |
SCOP_IS_________BASED_ON_MANUAL_COMPARISON_OF_STRUCTURES_BY_HUMAN_EXPERTS_WITH_NO_QUANTITATIVE_CRITERIA_TO_GROUP_PROTEINS.?$ |
| A. | entirely |
| B. | almost entirely |
| C. | not |
| D. | partially |
| Answer» C. not | |
| 5. |
CATH_is_a_combination_of_manual_curation_and_automated_procedure,_which_makes_the_process_less_subjective$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 6. |
Which of the following is untrue about SCOP and CATH? |
| A. | The definition for class in CATH is quite dissimilar to that in SCOP |
| B. | The definition for class in CATH is based on secondary structure content |
| C. | Architecture is a unique level in CATH, intermediate between fold and class |
| D. | The definition for class in CATH is similar to that in SCOP |
| Answer» E. | |
| 7. |
In CATH, Structural domain separation is carried by |
| A. | manual comparison only |
| B. | computer programs only |
| C. | human expertise only |
| D. | a combined effort of a human expert and computer programs |
| Answer» E. | |
| 8. |
Members within the ____ fold ______ have evolutionary relationships. |
| A. | same, always |
| B. | same, do not always |
| C. | one, always |
| D. | different, do not |
| Answer» C. one, always | |
| 9. |
Which of the following is untrue about SCOP? |
| A. | It is a database for comparing and classifying protein structures |
| B. | It is constructed almost entirely based on manual examination of protein structures |
| C. | The proteins are grouped into hierarchies of classes, folds, superfamilies, and families |
| D. | The SCOP families consist of proteins having low sequence identity (>30%) |
| Answer» E. | |
| 10. |
The last step in structure classification involves grouping proteins/domains of similar structures. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 11. |
The second step in structure classification is to separate structurally distinct domains within a structure. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 12. |
The first step in structure classification is to remove redundancy from databases. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 13. |
The classification results from both systems, SCOP and CATH are quite dissimilar. |
| A. | True |
| B. | False |
| Answer» C. | |