Marfan's syndrome is thought to be a mutation affecting

metabolism of homogentisic acid

insufficient thyroid production

Which of the following is not correct about the Coils and Loops?

The loops are often characterized by sharp turns or hairpin-like structures

If the connecting regions are completely irregular, they belong to random coils

Which of the following is not correct about the β-sheet?

β-Strands are stabilized by hydrogen bonds between residues of adjacent strands

A β-sheet is a fully extended configuration built up from several spatially adjacent regions of a polypeptide chain

Each region involved in forming the β-sheet is a β-strand

The β-strand conformation is pleated with main chain backbone zigzagging and side chains positioned on same sides of the sheet

β-Strands are stabilized by hydrogen bonds between residues of adjacent strands

Which of the following is not correct about the α-Helices?

Nearly all known α-helices are right handed, exhibiting a rightward spiral form

An α-helix has a main chain backbone conformation that resembles a corkscrew

Nearly all known α-helices are right handed, exhibiting a leftward spiral form

Nearly all known α-helices are right handed, exhibiting a rightward spiral form

In right handed helix, there are 3.6 amino acids per helical turn

WHICH_OF_THE_FOLLOWING_IS_NOT_CORRECT_ABOUT_THE_‚ÂÀ√≠‚ÄÖ√¢¬ß-SHEET??$#

‚âà√≠‚Äö√¢¬ß-Strands are stabilized by hydrogen bonds between residues of adjacent strands

A ‚âà√≠‚Äö√¢¬ß-sheet is a fully extended configuration built up from several spatially adjacent regions of a polypeptide chain

Each region involved in forming the ‚âà√≠‚Äö√¢¬ß-sheet is a ‚âà√≠‚Äö√¢¬ß-strand

The ‚âà√≠‚Äö√¢¬ß-strand conformation is pleated with main chain backbone zigzagging and side chains positioned on same sides of the sheet

‚âà√≠‚Äö√¢¬ß-Strands are stabilized by hydrogen bonds between residues of adjacent strands

Which_of_the_following_is_not_correct_about_the_Coils_and_Loops?$

The loops are often characterized by sharp turns or hairpin-like structures

If the connecting regions are completely irregular, they belong to random coils

Which of the following is not correct about the NMR?

NMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field

It stands for Nuclear Magnetic Resonance

NMR spectroscopy detects spinning patterns of atomic nuclei in a electric field

NMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field

Protein samples are labeled with radioisotopes such as 13C and 15N

Which of the following is not correct about the X-ray Crystallography?

In x-ray protein crystallography, proteins need to be grown into large crystals in which their positions are fixed in a repeated, ordered fashion

The protein crystals are illuminated with an intense x-ray beam

The x-rays are deflected by the electron clouds surrounding the atoms in the crystal producing a regular pattern of diffraction

The protein crystals are illuminated with an intense infrared beam

Which of the following is not correct about the Integral Membrane Proteins?

Most typical transmembrane segments are ‚âà√≠¬¨¬±-helices

Membrane proteins exist in lipid bilayers of cell membranes

The exterior of the proteins spanning the membrane must be very hydrophobic to be stable

The exterior of the proteins spanning the membrane must be very hydrophilic to be stable

Most typical transmembrane segments are ‚âà√≠¬¨¬±-helices

Which of the following is not correct about the ‚âà√≠¬¨¬±-Helices?#

Nearly all known ‚âà√≠¬¨¬±-helices are right handed, exhibiting a rightward spiral form

An ‚âà√≠¬¨¬±-helix has a main chain backbone conformation that resembles a corkscrew

Nearly all known ‚âà√≠¬¨¬±-helices are right handed, exhibiting a leftward spiral form

Nearly all known ‚âà√≠¬¨¬±-helices are right handed, exhibiting a rightward spiral form

In right handed helix, there are 3.6 amino acids per helical turn

Which of the following is not correct about the stabilizing Forces?

Electrostatic interactions are a significant stabilizing force in a protein structure

Protein structures from secondary to quaternary are maintained by noncovalent forces

They include electrostatic interactions but not van der Waals forces, and hydrogen bonding

Electrostatic interactions are a significant stabilizing force in a protein structure

Electrostatic interactions occur when excess negative charges in one region are neutralized by positive charges in another region

21 + Mcqs in Protein Structure Basics in Bioinformatics Page 1 McqOptions

1.	Marfan's syndrome is thought to be a mutation affecting
A.	hemoglobin synthesis
B.	collagen synthesis
C.	metabolism of homogentisic acid
D.	insufficient thyroid production
Answer» C. metabolism of homogentisic acid

Discussion

2.	Beta pleated sheets are examples of protein's
A.	primary structure
B.	secondary structure
C.	tertiary structure
D.	quaternary structure
Answer» C. tertiary structure

Discussion

3.	The four subunits of the hemoglobin (Hb) gene represent protein's
A.	primary structure
B.	secondary structure
C.	tertiary structure
D.	quaternary structure
Answer» E.

Discussion

4.	Globular proteins are usually insoluble.
A.	True
B.	False
Answer» C.

Discussion

5.	Which of the following is not correct about the Coils and Loops?
A.	They are regular structures
B.	They are irregular structures
C.	The loops are often characterized by sharp turns or hairpin-like structures
D.	If the connecting regions are completely irregular, they belong to random coils
Answer» B. They are irregular structures

Discussion

6.	Which of the following is not correct about the β-sheet?
A.	A β-sheet is a fully extended configuration built up from several spatially adjacent regions of a polypeptide chain
B.	Each region involved in forming the β-sheet is a β-strand
C.	The β-strand conformation is pleated with main chain backbone zigzagging and side chains positioned on same sides of the sheet
D.	β-Strands are stabilized by hydrogen bonds between residues of adjacent strands
Answer» D. β-Strands are stabilized by hydrogen bonds between residues of adjacent strands

Discussion

7.	Which of the following is not correct about the α-Helices?
A.	An α-helix has a main chain backbone conformation that resembles a corkscrew
B.	Nearly all known α-helices are right handed, exhibiting a leftward spiral form
C.	Nearly all known α-helices are right handed, exhibiting a rightward spiral form
D.	In right handed helix, there are 3.6 amino acids per helical turn
Answer» C. Nearly all known α-helices are right handed, exhibiting a rightward spiral form

Discussion

8.	WHICH_OF_THE_FOLLOWING_IS_NOT_CORRECT_ABOUT_THE_‚ÂÀ√≠‚ÄÖ√¢¬ß-SHEET??$#
A.	A ‚âà√≠‚Äö√¢¬ß-sheet is a fully extended configuration built up from several spatially adjacent regions of a polypeptide chain
B.	Each region involved in forming the ‚âà√≠‚Äö√¢¬ß-sheet is a ‚âà√≠‚Äö√¢¬ß-strand
C.	The ‚âà√≠‚Äö√¢¬ß-strand conformation is pleated with main chain backbone zigzagging and side chains positioned on same sides of the sheet
D.	‚âà√≠‚Äö√¢¬ß-Strands are stabilized by hydrogen bonds between residues of adjacent strands
Answer» D. ‚âà√≠‚Äö√¢¬ß-Strands are stabilized by hydrogen bonds between residues of adjacent strands

Discussion

9.	Globular proteins are usually insoluble.$
A.	True
B.	False
Answer» C.

Discussion

10.	Which_of_the_following_is_not_correct_about_the_Coils_and_Loops?$
A.	They are regular structures
B.	They are irregular structures
C.	The loops are often characterized by sharp turns or hairpin-like structures
D.	If the connecting regions are completely irregular, they belong to random coils
Answer» B. They are irregular structures

Discussion

11.	One can search a structure in PDB using the four-letter code or keywords related to its annotation.
A.	True
B.	False
Answer» B. False

Discussion

12.	Which of the following is not correct about the NMR?
A.	It stands for Nuclear Magnetic Resonance
B.	NMR spectroscopy detects spinning patterns of atomic nuclei in a electric field
C.	NMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field
D.	Protein samples are labeled with radioisotopes such as 13C and 15N
Answer» C. NMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field

Discussion

13.	Which of the following is not correct about the X-ray Crystallography?
A.	In x-ray protein crystallography, proteins need to be grown into large crystals in which their positions are fixed in a repeated, ordered fashion
B.	The protein crystals are illuminated with an intense x-ray beam
C.	The x-rays are deflected by the electron clouds surrounding the atoms in the crystal producing a regular pattern of diffraction
D.	The protein crystals are illuminated with an intense infrared beam
Answer» E.

Discussion

14.	Which of the following is not correct about the Integral Membrane Proteins?
A.	Membrane proteins exist in lipid bilayers of cell membranes
B.	The exterior of the proteins spanning the membrane must be very hydrophobic to be stable
C.	The exterior of the proteins spanning the membrane must be very hydrophilic to be stable
D.	Most typical transmembrane segments are ‚âà√≠¬¨¬±-helices
Answer» D. Most typical transmembrane segments are ‚âà√≠¬¨¬±-helices

Discussion

15.	Which of the following is not correct about the ‚âà√≠¬¨¬±-Helices?#
A.	An ‚âà√≠¬¨¬±-helix has a main chain backbone conformation that resembles a corkscrew
B.	Nearly all known ‚âà√≠¬¨¬±-helices are right handed, exhibiting a leftward spiral form
C.	Nearly all known ‚âà√≠¬¨¬±-helices are right handed, exhibiting a rightward spiral form
D.	In right handed helix, there are 3.6 amino acids per helical turn
Answer» C. Nearly all known ‚âà√≠¬¨¬±-helices are right handed, exhibiting a rightward spiral form

Discussion

16.	Which of the following is not correct about the stabilizing Forces?
A.	Protein structures from secondary to quaternary are maintained by noncovalent forces
B.	They include electrostatic interactions but not van der Waals forces, and hydrogen bonding
C.	Electrostatic interactions are a significant stabilizing force in a protein structure
D.	Electrostatic interactions occur when excess negative charges in one region are neutralized by positive charges in another region
Answer» C. Electrostatic interactions are a significant stabilizing force in a protein structure

Discussion

17.	A linear polymer of more than fifty amino acid residues is referred to as a ________
A.	dipeptide
B.	oligopeptide
C.	peptide
D.	polypeptide
Answer» E.

Discussion

18.	The peptide formation involves two amino acids covalently joined together between the carboxyl group of one amino acid and the amino group of another.
A.	True
B.	False
Answer» B. False

Discussion

19.	______ the smallest amino acid, has a hydrogen atom as the R group.
A.	valine
B.	proline
C.	Glycine
D.	threonine
Answer» D. threonine

Discussion

20.	Within the hydrophobic set of amino acids, they can be further divided into aliphatic and aromatic.
A.	True
B.	False
Answer» B. False

Discussion

21.	The building blocks of proteins are ______ naturally occurring amino acids, small molecules that contain a free amino group (NH2) and a free carboxyl group (COOH).
A.	ten
B.	twenty
C.	nine
D.	nineteen
Answer» C. nine

Discussion

Explore topic-wise MCQs in Bioinformatics.

Marfan's syndrome is thought to be a mutation affecting

Beta pleated sheets are examples of protein's

The four subunits of the hemoglobin (Hb) gene represent protein's

Globular proteins are usually insoluble.

Which of the following is not correct about the Coils and Loops?

Which of the following is not correct about the β-sheet?

Which of the following is not correct about the α-Helices?

WHICH_OF_THE_FOLLOWING_IS_NOT_CORRECT_ABOUT_THE_‚ÂÀ√≠‚ÄÖ√¢¬ß-SHEET??$#

Globular proteins are usually insoluble.$

Which_of_the_following_is_not_correct_about_the_Coils_and_Loops?$

One can search a structure in PDB using the four-letter code or keywords related to its annotation.

Which of the following is not correct about the NMR?

Which of the following is not correct about the X-ray Crystallography?

Which of the following is not correct about the Integral Membrane Proteins?

Which of the following is not correct about the ‚âà√≠¬¨¬±-Helices?#

Which of the following is not correct about the stabilizing Forces?

A linear polymer of more than fifty amino acid residues is referred to as a ________

The peptide formation involves two amino acids covalently joined together between the carboxyl group of one amino acid and the amino group of another.

______ the smallest amino acid, has a hydrogen atom as the R group.

Within the hydrophobic set of amino acids, they can be further divided into aliphatic and aromatic.

The building blocks of proteins are ______ naturally occurring amino acids, small molecules that contain a free amino group (NH2) and a free carboxyl group (COOH).