MCQOPTIONS
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MCQOPTIONS
This section includes 21 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Marfan's syndrome is thought to be a mutation affecting |
| A. | hemoglobin synthesis |
| B. | collagen synthesis |
| C. | metabolism of homogentisic acid |
| D. | insufficient thyroid production |
| Answer» C. metabolism of homogentisic acid | |
| 2. |
Beta pleated sheets are examples of protein's |
| A. | primary structure |
| B. | secondary structure |
| C. | tertiary structure |
| D. | quaternary structure |
| Answer» C. tertiary structure | |
| 3. |
The four subunits of the hemoglobin (Hb) gene represent protein's |
| A. | primary structure |
| B. | secondary structure |
| C. | tertiary structure |
| D. | quaternary structure |
| Answer» E. | |
| 4. |
Globular proteins are usually insoluble. |
| A. | True |
| B. | False |
| Answer» C. | |
| 5. |
Which of the following is not correct about the Coils and Loops? |
| A. | They are regular structures |
| B. | They are irregular structures |
| C. | The loops are often characterized by sharp turns or hairpin-like structures |
| D. | If the connecting regions are completely irregular, they belong to random coils |
| Answer» B. They are irregular structures | |
| 6. |
Which of the following is not correct about the β-sheet? |
| A. | A β-sheet is a fully extended configuration built up from several spatially adjacent regions of a polypeptide chain |
| B. | Each region involved in forming the β-sheet is a β-strand |
| C. | The β-strand conformation is pleated with main chain backbone zigzagging and side chains positioned on same sides of the sheet |
| D. | β-Strands are stabilized by hydrogen bonds between residues of adjacent strands |
| Answer» D. β-Strands are stabilized by hydrogen bonds between residues of adjacent strands | |
| 7. |
Which of the following is not correct about the α-Helices? |
| A. | An α-helix has a main chain backbone conformation that resembles a corkscrew |
| B. | Nearly all known α-helices are right handed, exhibiting a leftward spiral form |
| C. | Nearly all known α-helices are right handed, exhibiting a rightward spiral form |
| D. | In right handed helix, there are 3.6 amino acids per helical turn |
| Answer» C. Nearly all known α-helices are right handed, exhibiting a rightward spiral form | |
| 8. |
WHICH_OF_THE_FOLLOWING_IS_NOT_CORRECT_ABOUT_THE_‚ÂÀ√≠‚ÄÖ√¢¬ß-SHEET??$# |
| A. | A β-sheet is a fully extended configuration built up from several spatially adjacent regions of a polypeptide chain |
| B. | Each region involved in forming the β-sheet is a β-strand |
| C. | The β-strand conformation is pleated with main chain backbone zigzagging and side chains positioned on same sides of the sheet |
| D. | β-Strands are stabilized by hydrogen bonds between residues of adjacent strands |
| Answer» D. ‚âà√≠‚Äö√¢¬ß-Strands are stabilized by hydrogen bonds between residues of adjacent strands | |
| 9. |
Globular proteins are usually insoluble.$ |
| A. | True |
| B. | False |
| Answer» C. | |
| 10. |
Which_of_the_following_is_not_correct_about_the_Coils_and_Loops?$ |
| A. | They are regular structures |
| B. | They are irregular structures |
| C. | The loops are often characterized by sharp turns or hairpin-like structures |
| D. | If the connecting regions are completely irregular, they belong to random coils |
| Answer» B. They are irregular structures | |
| 11. |
One can search a structure in PDB using the four-letter code or keywords related to its annotation. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 12. |
Which of the following is not correct about the NMR? |
| A. | It stands for Nuclear Magnetic Resonance |
| B. | NMR spectroscopy detects spinning patterns of atomic nuclei in a electric field |
| C. | NMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field |
| D. | Protein samples are labeled with radioisotopes such as 13C and 15N |
| Answer» C. NMR spectroscopy detects spinning patterns of atomic nuclei in a magnetic field | |
| 13. |
Which of the following is not correct about the X-ray Crystallography? |
| A. | In x-ray protein crystallography, proteins need to be grown into large crystals in which their positions are fixed in a repeated, ordered fashion |
| B. | The protein crystals are illuminated with an intense x-ray beam |
| C. | The x-rays are deflected by the electron clouds surrounding the atoms in the crystal producing a regular pattern of diffraction |
| D. | The protein crystals are illuminated with an intense infrared beam |
| Answer» E. | |
| 14. |
Which of the following is not correct about the Integral Membrane Proteins? |
| A. | Membrane proteins exist in lipid bilayers of cell membranes |
| B. | The exterior of the proteins spanning the membrane must be very hydrophobic to be stable |
| C. | The exterior of the proteins spanning the membrane must be very hydrophilic to be stable |
| D. | Most typical transmembrane segments are α-helices |
| Answer» D. Most typical transmembrane segments are ‚âà√≠¬¨¬±-helices | |
| 15. |
Which of the following is not correct about the α-Helices?# |
| A. | An α-helix has a main chain backbone conformation that resembles a corkscrew |
| B. | Nearly all known α-helices are right handed, exhibiting a leftward spiral form |
| C. | Nearly all known α-helices are right handed, exhibiting a rightward spiral form |
| D. | In right handed helix, there are 3.6 amino acids per helical turn |
| Answer» C. Nearly all known ‚âà√≠¬¨¬±-helices are right handed, exhibiting a rightward spiral form | |
| 16. |
Which of the following is not correct about the stabilizing Forces? |
| A. | Protein structures from secondary to quaternary are maintained by noncovalent forces |
| B. | They include electrostatic interactions but not van der Waals forces, and hydrogen bonding |
| C. | Electrostatic interactions are a significant stabilizing force in a protein structure |
| D. | Electrostatic interactions occur when excess negative charges in one region are neutralized by positive charges in another region |
| Answer» C. Electrostatic interactions are a significant stabilizing force in a protein structure | |
| 17. |
A linear polymer of more than fifty amino acid residues is referred to as a ________ |
| A. | dipeptide |
| B. | oligopeptide |
| C. | peptide |
| D. | polypeptide |
| Answer» E. | |
| 18. |
The peptide formation involves two amino acids covalently joined together between the carboxyl group of one amino acid and the amino group of another. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 19. |
______ the smallest amino acid, has a hydrogen atom as the R group. |
| A. | valine |
| B. | proline |
| C. | Glycine |
| D. | threonine |
| Answer» D. threonine | |
| 20. |
Within the hydrophobic set of amino acids, they can be further divided into aliphatic and aromatic. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 21. |
The building blocks of proteins are ______ naturally occurring amino acids, small molecules that contain a free amino group (NH2) and a free carboxyl group (COOH). |
| A. | ten |
| B. | twenty |
| C. | nine |
| D. | nineteen |
| Answer» C. nine | |