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This section includes 17 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
TargetP is a neural network-based program, similar to SignalP. |
A. | True |
B. | False |
Answer» B. False | |
2. |
Which of the following is not one of the training sets in SignalP? |
A. | Prokaryotes |
B. | Eukaryotes |
C. | Gram-positive bacteria |
D. | Gram-negative bacteria |
Answer» B. Eukaryotes | |
3. |
Which of the following is an incorrect statement about SignalP? |
A. | It only uses neural networks |
B. | It only uses HMMs |
C. | It is a web-based program that predicts subcellular localization signals |
D. | It uses both neural networks and HMMs |
Answer» C. It is a web-based program that predicts subcellular localization signals | |
4. |
Chloroplast localization signals are also located in the __________ terminus and are about 25 to 100 residues in length, containing very few _______ charged residues but many hydroxylated residues such as serine. |
A. | N, negatively |
B. | C, negatively |
C. | C, positively |
D. | N, positively |
Answer» B. C, negatively | |
5. |
The signal sequences have a _________ consensus but contain some specific features. They all have a ______ core region preceded by one or more positively charged residues. |
A. | weak, hydrophilic |
B. | weak, hydrophobic |
C. | strong, hydrophilic |
D. | strong, hydrophilic |
Answer» C. strong, hydrophilic | |
6. |
Once the proteins are translocated within the organelles, protease cleavage takes place to remove the signal sequences and generate mature proteins. |
A. | True |
B. | False |
Answer» B. False | |
7. |
For many eukaryotic proteins, newly synthesized protein precursors have to be transported to specific membrane-bound compartments and be proteolytically processed to become functional. |
A. | True |
B. | False |
Answer» B. False | |
8. |
WHICH_OF_THE_FOLLOWING_IS_NOT_ONE_OF_THE_TRAINING_SETS_IN_SIGNALP??$ |
A. | Prokaryotes |
B. | Eukaryotes |
C. | Gram-positive bacteria |
D. | Gram-negative bacteria |
Answer» B. Eukaryotes | |
9. |
TargetP_is_a_neural_network-based_program,_similar_to_SignalP.$ |
A. | True |
B. | False |
Answer» B. False | |
10. |
Which of the following is an incorrect statement about Signal? |
A. | It only uses neural networks |
B. | It only uses HMMs |
C. | It is a web-based program that predicts subcellular localization signals |
D. | It uses both neural networks and HMMs |
Answer» C. It is a web-based program that predicts subcellular localization signals | |
11. |
Chloroplast localization signals consist of two adjacent signal peptides, one for targeting the proteins to the stromaportion of the chloroplast before being cleaved and the other for targeting the remaining portion of the proteins to the thylakoids. |
A. | True |
B. | False |
Answer» B. False | |
12. |
Chloroplast localization signals are also located in the ___-terminus and are about 25 to 100 residues in length, containing very few _______ charged residues but many hydroxylated residues such as serine. |
A. | N, negatively |
B. | C, negatively |
C. | C, positively |
D. | N, positively |
Answer» B. C, negatively | |
13. |
The signal sequences are typically _______ residues long, rich in _____ charged residues such as arginines as well as hydroxyl residues such as serines and threonines, but devoid of ______ charged residues. |
A. | 28 to 80, positively, negatively |
B. | 300 to 800, negatively, positively |
C. | 28 to 80, negatively, positively |
D. | 300 to 500, positively, negatively |
Answer» B. 300 to 800, negatively, positively | |
14. |
The signal sequences have a ___consensus but contain some specific features. They all have a ______ core region preceded by one or more positively charged residues. |
A. | weak, hydrophilic |
B. | weak, hydrophobic |
C. | strong, hydrophilic |
D. | strong, hydrophilic |
Answer» C. strong, hydrophilic | |
15. |
Once the proteins are translocated within the organelles, protease cleavage takes place to remove the signal sequences and generate mature proteins |
A. | True |
B. | False |
Answer» B. False | |
16. |
For many eukaryotic proteins, newly synthesized protein precursors have to be transported to specific membrane-bound compartments and be proteolytically processed to become functional |
A. | True |
B. | False |
Answer» B. False | |
17. |
Which of the following is an incorrect statement about the terminologies related to protein sorting? |
A. | Subcellular localization is an integral part of protein functionality |
B. | Many proteins exhibit functions only after being transported to certain compartments of the cell |
C. | All the proteins exhibit functions after being transported to certain compartments of the cell |
D. | Protein sorting is also known as protein targeting |
Answer» D. Protein sorting is also known as protein targeting | |