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This section includes 7 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
TargetP is a neural network-based program, similar to SignalP. |
A. | True |
B. | False |
Answer» B. False | |
2. |
Which of the following is not one of the training sets in SignalP? |
A. | Prokaryotes |
B. | Eukaryotes |
C. | Gram-positive bacteria |
D. | Gram-negative bacteria |
Answer» B. Eukaryotes | |
3. |
Which of the following is an incorrect statement about SignalP? |
A. | It only uses neural networks |
B. | It only uses HMMs |
C. | It is a web-based program that predicts subcellular localization signals |
D. | It uses both neural networks and HMMs |
Answer» C. It is a web-based program that predicts subcellular localization signals | |
4. |
Chloroplast localization signals are also located in the __________ terminus and are about 25 to 100 residues in length, containing very few _______ charged residues but many hydroxylated residues such as serine. |
A. | N, negatively |
B. | C, negatively |
C. | C, positively |
D. | N, positively |
Answer» B. C, negatively | |
5. |
The signal sequences have a _________ consensus but contain some specific features. They all have a ______ core region preceded by one or more positively charged residues. |
A. | weak, hydrophilic |
B. | weak, hydrophobic |
C. | strong, hydrophilic |
D. | strong, hydrophilic |
Answer» C. strong, hydrophilic | |
6. |
Once the proteins are translocated within the organelles, protease cleavage takes place to remove the signal sequences and generate mature proteins. |
A. | True |
B. | False |
Answer» B. False | |
7. |
For many eukaryotic proteins, newly synthesized protein precursors have to be transported to specific membrane-bound compartments and be proteolytically processed to become functional. |
A. | True |
B. | False |
Answer» B. False | |