Explore topic-wise MCQs in Bioinformatics.

This section includes 16 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

In the zinc finger, which residues in this sequence motif form ligands to a zinc ion?

A. Cysteine and histidine
B. Cysteine and arginine
C. Histidine and proline
D. Histidine and arginine
Answer» B. Cysteine and arginine
Discussion
2.

Which of the following is not the function of Short Linear Motifs?

A. Irreversible cleavage of the peptide at the SLiM
B. Reversible cleavage of the peptide at the SLiM
C. Moiety addition at targeted sites on SLiM
D. Structural modifications of the peptide backbone
Answer» B. Reversible cleavage of the peptide at the SLiM
Discussion
3.

The protein structural motif domain- helix loop helix are contained by all of the following except ________

A. Scleraxis
B. Neurogenins
C. Transcription Factor 4
D. Leucine zipper
Answer» E.
Discussion
4.

Motifs that can form α/β horseshoes conformation are rich with which protein residue?

A. Proline
B. Arginine
C. Valine
D. Leucine
Answer» E.
Discussion
5.

Which of the following least describes Long Loop β-hairpins?

A. They are Often referred to as a ‘random coil’ conformation
B. Generally they are referred to as the β-meander supersecondary structure
C. Loop looks similar to the Greek Letter Ω
D. Wide-range of conformations with very specific sequence preferences
Answer» E.
Discussion
6.

Which of the following is false about the ‘loop’ structure in proteins?

A. They connect helices and sheets
B. They are more tolerant of mutations
C. They are more flexible and can adopt multiple conformations
D. They are never the components of active sites
Answer» E.
Discussion
7.

IN_THE_ZINC_FINGER,_WHICH_RESIDUES_IN_THIS_SEQUENCE_MOTIF_FORM_LIGANDS_TO_A_ZINC_ION??$

A. Cysteine and histidine
B. Cysteine and arginine
C. Histidine and proline
D. Histidine and arginine
Answer» B. Cysteine and arginine
Discussion
8.

WHICH_OF_THE_FOLLOWING_IS_NOT_THE_FUNCTION_OF_SHORT_LINEAR_MOTIFS??$

A. Irreversible cleavage of the peptide at the SLiM
B. Reversible cleavage of the peptide at the SLiM
C. Moiety addition at targeted sites on SLiM
D. Structural modifications of the peptide backbone
Answer» B. Reversible cleavage of the peptide at the SLiM
Discussion
9.

The protein structural motif domain- helix loop helix are contained by all of the following except_______?

A. Scleraxis
B. Neurogenins
C. Transcription Factor 4
D. Leucine zipper
Answer» E.
Discussion
10.

Which of the following wrongly describes protein domains?

A. They are made up of one secondary structure
B. Defined as independently foldable units
C. They are stable structures as compared to motifs
D. They are separated by linker regions
Answer» B. Defined as independently foldable units
Discussion
11.

Motifs that can form α/β horseshoes conformation are rich with which protein residue?$

A. Proline
B. Arginine
C. Valine
D. Leucine
Answer» E.
Discussion
12.

Which of the following least describes Long Loop β-hairpins?$

A. They are Often referred to as a ‘random coil’ conformation
B. Generally they are referred to as the β-meander supersecondary structure
C. Loop looks similar to the Greek Letter Ω
D. Wide-range of conformations with very specific sequence preferences
Answer» E.
Discussion
13.

Which of the common structural motifs are described wrongly?

A. β-hairpin – adjacent antiparallel strands
B. Greek key – 4 adjacent antiparallel strand
C. β-α-β – 2 parallel strands connected by helix
D. β-α-β – 2 antiparallel strands connected by helix
Answer» E.
Discussion
14.

Which of the following is false about the ‘loop’ structure in proteins?$

A. They connect helices and sheets
B. They are more tolerant of mutations
C. They are more flexible and can adopt multiple conformations
D. They are never the components of active sites
Answer» E.
Discussion
15.

On average, what is the length of a typical domain?

A. About 100 residues
B. About 300 residues
C. About 500 residues
D. About 900 residues
Answer» B. About 300 residues
Discussion
16.

What is the length of a motif, in terms of amino acids residue?

A. 30- 60
B. 10- 20
C. 70- 90
D. 1- 10
Answer» C. 70- 90
Discussion