MCQOPTIONS
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MCQOPTIONS
This section includes 6 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following is untrue regarding the STRING? |
| A. | Search Tool for the Retrieval of Interacting Genes/Proteins |
| B. | Functional associations include only the direct protein-protein interactions |
| C. | It is based on combined evidence of gene linkage, gene fusion and phylogenetic profiles |
| D. | It is a web server that predicts gene and protein functional associations |
| Answer» C. It is based on combined evidence of gene linkage, gene fusion and phylogenetic profiles | |
| 2. |
Which of the following is untrue regarding the predicting Interactions Based on Phylogenetic Information? |
| A. | Proteins do not operate as a complex |
| B. | This method detects the co-presence or co-absence of orthologs across a number of genomes |
| C. | Protein interactions can be predicted using phylogenetic profiles |
| D. | Phylogenetic profile are defined as patterns of gene pairs that are concurrently present or absent across genomes |
| Answer» B. This method detects the co-presence or co-absence of orthologs across a number of genomes | |
| 3. |
In Predicting Interactions Based on Gene Neighbors if a certain gene linkage is found to be indeed conserved across divergent genomes, it can be used as a strong indicator of formation of an operon that encodes proteins that are functionally and even physically coupled. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 4. |
Which of the following is untrue regarding the Predicting Interactions Based on Domain Fusion? |
| A. | It is based on gene fusion events |
| B. | Predicting protein protein interactions is called the Rosetta stone method |
| C. | A fused protein often reveals relationships between its domain components |
| D. | A fused protein doesn t necessarily reveal about the relationships between its domain components |
| Answer» E. | |
| 5. |
An alternative approach to determining protein protein interactions is to use a large-scale affinity purification technique that involves attaching fusion tags to proteins and purifying the associated protein complexes in an affinity chromatography column. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 6. |
If the bait and prey proteins _______ they bring the DNA-binding and trans-activation domains in such close proximity that they reconstitute the function of the transcription activator, turning ____ the expression of a reporter gene as a result. Which of the following is not the correct pair of blanks? |
| A. | physically interact, on |
| B. | do not interact, on |
| C. | do not interact, off |
| D. | stop interacting, off |
| Answer» C. do not interact, off | |