Which of the following statements about PANTHER and TIGRFAMs databases is incorrect regarding its features?

PANTHER is a large collection of protein families that have been subdivided into functionally related subfamilies, using human expertise

TIGRFAMs provides a tool for identifying functionally related proteins based on sequence homology

TIGRFAMs is a collection of protein families, featuring curated multiple sequence alignments, hidden Markov models (HMMs) and annotation

Hidden Markov models (HMMs) are not used in PANTHER

PANTHER is a large collection of protein families that have been subdivided into functionally related subfamilies, using human expertise

Which of the following statements about CATH-Gene3D and HAMAP databases is incorrect regarding its features?

HAMAP profiles are manually created by expert curators they identify proteins that are part of well-conserved bacterial, archaeal and plastid-encoded proteins families or subfamilies.

CATH-Gene3D describes protein families and domain architectures in complete genomes

In CATH-Gene3D the functional annotation is provided to proteins from single resource

HAMAP profiles are manually created by expert curators they identify proteins that are part of well-conserved bacterial, archaeal and plastid-encoded proteins families or subfamilies.

HAMAP stands for High-quality Automated and Manual Annotation of microbial Proteomes

Which of the following statements about SCOP is incorrect regarding its features?

It aims to determine the evolutionary relationship between proteins

Proteins with the same shapes but having little sequence or functional similarity are placed in different super families, and are assumed to have only a very distant common ancestor

Proteins having the same shape and some similarity of sequence and/or function are placed in families , and are assumed to have a closer common ancestor

SCOP was created in 1994 in the Centre of Protein Engineering and the University College London

It aims to determine the evolutionary relationship between proteins

Explore topic-wise MCQs in Bioinformatics.

This section includes 3 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.	Which of the following statements about PANTHER and TIGRFAMs databases is incorrect regarding its features?
A.	TIGRFAMs provides a tool for identifying functionally related proteins based on sequence homology
B.	TIGRFAMs is a collection of protein families, featuring curated multiple sequence alignments, hidden Markov models (HMMs) and annotation
C.	Hidden Markov models (HMMs) are not used in PANTHER
D.	PANTHER is a large collection of protein families that have been subdivided into functionally related subfamilies, using human expertise
Answer» D. PANTHER is a large collection of protein families that have been subdivided into functionally related subfamilies, using human expertise

Discussion

2.	Which of the following statements about CATH-Gene3D and HAMAP databases is incorrect regarding its features?
A.	CATH-Gene3D describes protein families and domain architectures in complete genomes
B.	In CATH-Gene3D the functional annotation is provided to proteins from single resource
C.	HAMAP profiles are manually created by expert curators they identify proteins that are part of well-conserved bacterial, archaeal and plastid-encoded proteins families or subfamilies.
D.	HAMAP stands for High-quality Automated and Manual Annotation of microbial Proteomes
Answer» C. HAMAP profiles are manually created by expert curators they identify proteins that are part of well-conserved bacterial, archaeal and plastid-encoded proteins families or subfamilies.

Discussion

3.	Which of the following statements about SCOP is incorrect regarding its features?
A.	Proteins with the same shapes but having little sequence or functional similarity are placed in different super families, and are assumed to have only a very distant common ancestor
B.	Proteins having the same shape and some similarity of sequence and/or function are placed in families , and are assumed to have a closer common ancestor
C.	SCOP was created in 1994 in the Centre of Protein Engineering and the University College London
D.	It aims to determine the evolutionary relationship between proteins
Answer» D. It aims to determine the evolutionary relationship between proteins

Discussion