Explore topic-wise MCQs in Bioinformatics.

This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

In CONPRO, for each program, the highest score prediction is taken as the promoter in the region.

A. True
B. False
Answer» B. False
2.

Which of the following is incorrect regarding CONPRO?

A. It is a web-based program that uses a consensus method
B. It is used to identify promoter elements for human DNA
C. cDNA does not play a role in prediction
D. The program uses the information to search the human genome database for the position of the gene
Answer» D. The program uses the information to search the human genome database for the position of the gene
3.

TSSW is a web program that distinguishes promoter sequences from non-promoter sequences based on a combination of unique content information such as hexamer/trimer frequencies and signal information such the TATA box in the promoter region.

A. True
B. False
Answer» B. False
4.

The input for the neural network includes parameters for sequence physical properties, such as ______

A. DNA bendability
B. Signals such as the TATA box
C. Signals such as initiator box
D. Signals such as CpAA islands
Answer» E.
5.

McPromoter, a web-based program, uses a neural network to make promoter predictions.

A. True
B. False
Answer» B. False
6.

Which of the following is incorrect regarding First EF?

A. It is a program that predicts promoters for bacterial DNA
B. It is a web-based program that predicts promoters for human DNA
C. It stands for First Exon Finder
D. It integrates gene prediction with promoter prediction
Answer» B. It is a web-based program that predicts promoters for human DNA
7.

Which of the following is incorrect regarding Cluster-Buster?

A. It is an HMM-based web-based program
B. A query sequence is scanned with a window size of 1 kb for putative regulatory motifs using motif HMMs
C. It works by detecting a region of high concentration of unknown transcription factor binding sites and regulatory motifs at the initiation
D. It is designed to find clusters of regulatory binding sites
Answer» D. It is designed to find clusters of regulatory binding sites
8.

Which of the following is incorrect regarding Eponine?

A. It is a web-based program that predicts transcription start sites
B. It is a web-based program that particularly predicts tranpososons and retropososons
C. The regulatory sites include the TATA box, the CCAAT box, and CpG islands
D. It is based on a series of pre-constructed PSSMs of several regulatory sites
Answer» C. The regulatory sites include the TATA box, the CCAAT box, and CpG islands
9.

CpGProD is a web-based program that predicts promoters containing a high density of CpG islands _______

A. in archea genomic sequences
B. in mammalian genomic sequences
C. in eukaryotic and bacterial genomic sequences
D. only in bacterial genomic sequences
Answer» C. in eukaryotic and bacterial genomic sequences
10.

The eukaryotic transcription initiation is less dependent on transcription factors.

A. True
B. False
Answer» C.