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This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
In CONPRO, for each program, the highest score prediction is taken as the promoter in the region. |
A. | True |
B. | False |
Answer» B. False | |
2. |
Which of the following is incorrect regarding CONPRO? |
A. | It is a web-based program that uses a consensus method |
B. | It is used to identify promoter elements for human DNA |
C. | cDNA does not play a role in prediction |
D. | The program uses the information to search the human genome database for the position of the gene |
Answer» D. The program uses the information to search the human genome database for the position of the gene | |
3. |
TSSW is a web program that distinguishes promoter sequences from non-promoter sequences based on a combination of unique content information such as hexamer/trimer frequencies and signal information such the TATA box in the promoter region. |
A. | True |
B. | False |
Answer» B. False | |
4. |
The input for the neural network includes parameters for sequence physical properties, such as ______ |
A. | DNA bendability |
B. | Signals such as the TATA box |
C. | Signals such as initiator box |
D. | Signals such as CpAA islands |
Answer» E. | |
5. |
McPromoter, a web-based program, uses a neural network to make promoter predictions. |
A. | True |
B. | False |
Answer» B. False | |
6. |
Which of the following is incorrect regarding First EF? |
A. | It is a program that predicts promoters for bacterial DNA |
B. | It is a web-based program that predicts promoters for human DNA |
C. | It stands for First Exon Finder |
D. | It integrates gene prediction with promoter prediction |
Answer» B. It is a web-based program that predicts promoters for human DNA | |
7. |
Which of the following is incorrect regarding Cluster-Buster? |
A. | It is an HMM-based web-based program |
B. | A query sequence is scanned with a window size of 1 kb for putative regulatory motifs using motif HMMs |
C. | It works by detecting a region of high concentration of unknown transcription factor binding sites and regulatory motifs at the initiation |
D. | It is designed to find clusters of regulatory binding sites |
Answer» D. It is designed to find clusters of regulatory binding sites | |
8. |
Which of the following is incorrect regarding Eponine? |
A. | It is a web-based program that predicts transcription start sites |
B. | It is a web-based program that particularly predicts tranpososons and retropososons |
C. | The regulatory sites include the TATA box, the CCAAT box, and CpG islands |
D. | It is based on a series of pre-constructed PSSMs of several regulatory sites |
Answer» C. The regulatory sites include the TATA box, the CCAAT box, and CpG islands | |
9. |
CpGProD is a web-based program that predicts promoters containing a high density of CpG islands _______ |
A. | in archea genomic sequences |
B. | in mammalian genomic sequences |
C. | in eukaryotic and bacterial genomic sequences |
D. | only in bacterial genomic sequences |
Answer» C. in eukaryotic and bacterial genomic sequences | |
10. |
The eukaryotic transcription initiation is less dependent on transcription factors. |
A. | True |
B. | False |
Answer» C. | |