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This section includes 6 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
To increase the specificity of prediction, a unique feature of eukaryotic promoter is employed, which is the presence of CpG islands. |
A. | True |
B. | False |
Answer» B. False | |
2. |
Which of the following is incorrect regarding the Prediction for Eukaryotes? |
A. | The consensus patterns are only derived from bioinformatics studies |
B. | The experimentally determined DNA binding sites are compiled into profiles and stored in a database for scanning an unknown sequence to find similar conserved patterns |
C. | The consensus patterns are derived from experimentally determined DNA binding sites |
D. | The ab initio method for predicting eukaryotic promoters and regulatory elements relies on searching the input sequences for matching of consensus patterns of known promoters and regulatory elements |
Answer» B. The experimentally determined DNA binding sites are compiled into profiles and stored in a database for scanning an unknown sequence to find similar conserved patterns | |
3. |
Which of the following is incorrect regarding FindTerm? |
A. | It is a program for searching bacterial -independent termination signals located at the end of operons |
B. | It is a program for searching bacterial -dependent termination signals located within the operons |
C. | The predictions are made based on matching of known profiles of the termination signals combined with energy calculations |
D. | It is available from the same site as FGENES and BPROM |
Answer» C. The predictions are made based on matching of known profiles of the termination signals combined with energy calculations | |
4. |
In BPROM, once the operons are assigned, the program is able to predict putative promoter sequences. |
A. | True |
B. | False |
Answer» B. False | |
5. |
Once an operon structure is known ______ for the presence of a promoter and regulatory elements _____ in the operon do not possess such DNA elements. |
A. | only the first gene is predicted, whereas other genes |
B. | only the first hundred genes are predicted, whereas next few genes |
C. | only first two genes are predicted, whereas next few genes |
D. | only first ten genes are predicted, whereas next few genes |
Answer» B. only the first hundred genes are predicted, whereas next few genes | |
6. |
To improve the specificity of prediction, some algorithms selectively ______ coding regions and focus on the upstream regions________ which are most likely to contain promoters. In that sense, promoter prediction and gene prediction are coupled. |
A. | include, (0.5 to 2.0 kb) only |
B. | include, (0.5 to 2.0 Mb) only |
C. | exclude, (0.5 to 2.0 Mb) only |
D. | exclude, (0.5 to 2.0 kb) only |
Answer» E. | |