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This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
1. |
Two commonly encountered examples are the Genetics Computer Group’s MSF format and the CLUSTALW ALN format. |
A. | True |
B. | False |
Answer» B. False | |
2. |
MACAW is a local multiple sequence alignment program only. |
A. | True |
B. | False |
Answer» C. | |
3. |
GDE (Genetic Data Environment) provides a general interface on UNIX machines for sequence analysis, sequence alignment editing, and display. |
A. | True |
B. | False |
Answer» B. False | |
4. |
If the data set is _______ then unless the motif has __________ amino acids in each column, the column frequencies in the motif may not be highly representative of all other occurrences of the motif. |
A. | small, distinct |
B. | small, almost identical |
C. | large, almost identical |
D. | large, distinct |
Answer» C. large, almost identical | |
5. |
MACAW_IS_A_LOCAL_MULTIPLE_SEQUENCE_ALIGNMENT_PROGRAM_ONLY.?$ |
A. | True |
B. | False |
Answer» C. | |
6. |
Two_commonly_encountered_examples_are_the_Genetics_Computer_Group’s_MSF_format_and_the_CLUSTALW_ALN_format.$# |
A. | True |
B. | False |
Answer» B. False | |
7. |
GDE (Genetic Data Environment) provides a general interface on UNIX machines for sequence analysis, sequence alignment editing, and display? |
A. | True |
B. | False |
Answer» B. False | |
8. |
Which of the following is not a feature of editors and formatters? |
A. | provision for displaying the sequence on a color monitor with residue colors to aid in a clear visual representation of the alignment |
B. | recognition of the multiple sequence format that was output by the MSA (Multiple Sequence Alignment) program |
C. | maintenance of the alignment in a suitable format when the editing is completed |
D. | disallowing shading conserved residues in the alignment |
Answer» E. | |
9. |
Even if many pseudocounts are added in comparison to real sequence counts, the amino acid frequencies will not have any effect or influence. |
A. | True |
B. | False |
Answer» C. | |
10. |
If the data set is _______, then unless the motif has __________ amino acids in each column, the column frequencies in the motif may not be highly representative of all other occurrences of the motif. |
A. | small, distinct |
B. | small, almost identical |
C. | large, almost identical |
D. | large, distinct |
Answer» C. large, almost identical | |
11. |
If a good sampling of sequences is _______ the number of sequences is _________ and the motif structure is ________ it should, in principle, be possible to obtain frequencies highly representative of the same motif in other sequences also. |
A. | available, sufficiently large, not too complex |
B. | unavailable, sufficiently large, not too complex |
C. | unavailable, sufficiently small, not too complex |
D. | available, sufficiently large, too complex |
Answer» B. unavailable, sufficiently large, not too complex | |
12. |
Two considerations arise in trying to tune the PSSM so that it adequately represents the training sequences. Which of the following is not their description? |
A. | If a given column in 20 sequences has only isoleucine, it is not very likely that a different amino acid will be found in other sequences with that motif because the residue is probably important for function |
B. | If a given column in 20 sequences has only isoleucine, it is very likely that a different amino acid will be found in other sequences with that motif because the residue is probably important for function |
C. | If the number of sequences with the found motif is large and reasonably diverse, the sequences represent a good statistical sampling of all sequences that are ever likely to be found with that same motif |
D. | Another column in the motif from the 20 sequences may have several amino acids, and some amino acids may not be represented at all |
Answer» C. If the number of sequences with the found motif is large and reasonably diverse, the sequences represent a good statistical sampling of all sequences that are ever likely to be found with that same motif | |
13. |
The quality and quantity of information provided by the PSSM also varies for ________ in the motif. |
A. | each row |
B. | each column |
C. | rows and columns |
D. | neither the rows nor the columns |
Answer» C. rows and columns | |
14. |
Analysis of s for conserved blocks of sequence leads to production of the position-specific scoring matrix. |
A. | True |
B. | False |
Answer» B. False | |