Explore topic-wise MCQs in GPAT.

This section includes 925 Mcqs, each offering curated multiple-choice questions to sharpen your GPAT knowledge and support exam preparation. Choose a topic below to get started.

251.

Generally, Stability testing is employed for...........

A. Delivering evidences of the change in quality of the drug product with time.
B. Confirming shelf life for the drug product.
C. Determining container closure system suitability.
D. All of the above
Answer» E.
252.

High viscosity indicates one of the following relationships in a system. Which is relevant?

A. free from intermolecular interactions
B. intermolecular attractions are stronger
C. intermolecular attractions are weaker
D. shape of the molecules is spherical
Answer» C. intermolecular attractions are weaker
253.

Silica gel is an example for the type of gel:

A. dilatants
B. elastic
C. rigid
D. thixotropic
Answer» D. thixotropic
254.

The angle of repose values are utilized to:

A. measure the movement of granules from hopper to the table of tabletting/capsule machine
B. select proper containers for capsules of a given mass of powders
C. study the absorption of drugs
D. understand dissolution of medicament
Answer» B. select proper containers for capsules of a given mass of powders
255.

........... is the time necessary for the concentration of the reactant to decrease to 90% of its originalconcentration.

A. Product life
B. Shelf life
C. Half life
D. None of the above
Answer» C. Half life
256.

............ exists when dispersed solid particles in a suspension retain change in relation their adjoiningliquid medium.

A. Surface area
B. Surface potential
C. Surface volume
D. None of the above
Answer» C. Surface volume
257.

Accelerated stability testing is done to

A. predict shelf of the formulation
B. Predict dissociation constant
C. Predict diffusion constant
D. Determine activation energy
Answer» B. Predict dissociation constant
258.

Andreasen pipette is widely used method to determine particle size distribution by

A. Microscopy method
B. sedimentation method
C. Sieving method
D. All of the above
Answer» C. Sieving method
259.

Dilatant flow is characterized as a reverse phenomenon of:

A. newtoniam flow
B. plastic flow
C. pseudoplastic flow
D. rheopexy
Answer» D. rheopexy
260.

The potential difference develop when particles settle under the influence of gravity is called

A. Streaming potential
B. Oxidation Potential
C. Reduction potential
D. Sedimentation potential
Answer» E.
261.

The integral rate equation for a reaction (in common notation) is written as log C = log Co - (kt/2.303).When a graph is drawn log c vs. t, the slope will be:

A. negative
B. one
C. Positive
D. Zero
Answer» B. one
262.

Creaming is a.......... process

A. reversible
B. irreversible
C. A & B
D. difficult to predict
Answer» B. irreversible
263.

The reaction rate constant (k) is 2.0 x 10-3 min.-1 for aspirin hydrolysis in 0.1 N hydrochloric acid at1mg/ml concentration. Under same conditions, if the product contains aspirin 4 mg/ml of the initial concentration, the k value in minutes-1 will be:

A. 0.5 x l0-3
B. 2.0 x 10-3
C. 4.0 x 10-3
D. 8.0 x 10-3
Answer» C. 4.0 x 10-3
264.

Andreasen apparatus consists of:

A. balance
B. electrodes
C. hydrometer
D. pipette
Answer» D. pipette
265.

Which one of these preparations is NOT qualified as a suspension.

A. barium meal for radiodiagnostic use
B. calamine lotion for antiseptic use
C. procaine penicillin G for intramuscular injection
D. vitamin B complex tonic as nutritional supplement
Answer» E.
266.

Suspension is example of

A. Biphasic liquid dosage form
B. Solid dosage form
C. Semi-solid dosage form
D. All of the above
Answer» B. Solid dosage form
267.

In the equation, Rate = k[C]c[D]d, the order of the above reaction is

A. k
B. C + D
C. [C] *[D]
D. c + d
Answer» E.
268.

Aerosol is the reverse of :

A. emulsion
B. liquid foam
C. smoke
D. solid foam
Answer» C. smoke
269.

Dispersion of acacia in water gives the colloid of type:

A. association
B. negative
C. neutral
D. positive
Answer» C. neutral
270.

The term rheology was invented by

A. Bingham and Crawford
B. Newton
C. Michaelis and Menten
D. Watson and Crick
Answer» B. Newton
271.

If ions of similar charges involve in reaction it will............rate of reaction.

A. Increases
B. Decreases
C. Remains constant
D. None of the above
Answer» C. Remains constant
272.

The equal distribution of all the ions in solution retain by……

A. Electric forces
B. Thermal motion
C. Both of the above
D. None of the above
Answer» D. None of the above
273.

An emulsifier is considered to be ideal, if it is soluble in

A. Aqueous phase
B. oily phase
C. A & B
D. none of the above
Answer» D. none of the above
274.

A mixture of span 20 and tween 20 forms....... type of emulsion

A. W/O
B. O/W
C. Milky
D. Hard
Answer» B. O/W
275.

..........technique is utilized only during determination of order of reaction, when the rate law involvedby only single concentration term.

A. The concentration
B. The half of the concentration
C. The square of the concentration
D. None of the above
Answer» D. None of the above
276.

Name the type of colloidal dispersion to which electrolytes are normally added in small quantities tostabilize:

A. association
B. lyophilic
C. lyophobic
D. micellar
Answer» D. micellar
277.

Which one of these methods is the MOST effective in preventing the rate of hydrolysis?

A. buffer
B. complexation
C. removal of water
D. suppression of solubility
Answer» D. suppression of solubility
278.

Which one of the following properties is applicable to suspensions?

A. Brownian movement
B. laminar flow
C. rapid rate of sedimentation
D. strokes’ law
Answer» D. strokes’ law
279.

For a flocculated suspension, one of the following criterion is satisfied or established

A. High inter-particle repulsions
B. strong inter-particle attractions
C. weak inter-particle attractions
D. weak inter-particle repulsions
Answer» D. weak inter-particle repulsions
280.

Addition of alcohol to a hydrophilic colloid leads to:

A. crystallization
B. hydration
C. precipitation
D. stabilization
Answer» D. stabilization
281.

.... is the number of particles per unit weight.

A. Particle volume
B. Particle number
C. Particle mean
D. Particle weight
Answer» C. Particle mean
282.

The type of particle diameter that is obtained by microscope method of evaluation is:

A. projected
B. stokes’
C. volume
D. volume-surface
Answer» B. stokes’
283.

An emulsifier can be regarded as superior, if its mechanism of action is based on the principle of:

A. developing solid adsorption film
B. forming monomolecular adsorption film
C. generating multimolecular adsorption film
D. increasing interfacial energy
Answer» C. generating multimolecular adsorption film
284.

A shear stress-shear rate relationship is generally explained in the form of curve i.e. or………

A. Rheogram
B. Consistency curve
C. Both of the above
D. None of the above
Answer» D. None of the above
285.

On commercial scale, emulsions are prepared by::

A. centrifugation
B. dialysis
C. freezing
D. homogenization
Answer» E.
286.

The term ‘light’ as applied to pharmaceutical powders means:

A. low bulk density
B. low granule density
C. low true density
D. slightly coloured
Answer» C. low true density
287.

It is difficult to express the size of particles in a meaningful diameter.

A. irregular in shape
B. irregular surface
C. spherical shape
D. uniform in size
Answer» B. irregular surface
288.

The distribution of globules is not uniform in an emulsion. This stage is termed as:

A. breaking
B. caking
C. coalescence
D. creaming
Answer» E.
289.

Which of the following is not a viscometers

A. Capillary
B. Falling Sphere
C. Rotational
D. Drop weight
Answer» E.
290.

In practice, an acceptable suspension should have particles:

A. of nearly 0.1 micrometer
B. which can be readily re-dispersible after they settle
C. which should form a cake after settling
D. should not settle
Answer» C. which should form a cake after settling
291.

A zero-order reaction is a reaction having rate of concentration of reactant.

A. Dependent
B. Partially dependent
C. Independent
D. None of the above
Answer» D. None of the above
292.

In general, Newtonian fluids are expressed in terms of viscosity. A corresponding expression in nonNewtonian fluids (in terms of viscosity) is:

A. apparent
B. dynamic
C. intrinsic
D. kinematic
Answer» B. dynamic
293.

Regarding the influence of the solvent on the rate of reaction, solvents having the internal pressure:

A. HIGHER produce products with HIGHER internal pressure
B. HIGHER favour the formation of products having LOWER internal pressure
C. LOWER yield products having HIGHER internal pressure
D. LOWER retard the formation of products with LOWER internal pressure
Answer» B. HIGHER favour the formation of products having LOWER internal pressure
294.

The value of sedimentation volume (F) gives a knowledge about the____________of the suspension

A. physical stability
B. Incompatibility
C. Solubility
D. All of the above
Answer» B. Incompatibility
295.

Pseudoplastic flow is generally exhibited by

A. Jellies
B. Suspension
C. Lotion
D. Colloids
Answer» B. Suspension
296.

When charcoal powder is dusted on the surface of water, the contact angle (in degrees) that thecharcoal exhibits is:

A. zero
B. one
C. 90
D. 180
Answer» E.
297.

Kinematic viscosity is the ratio of dynamic viscosity to the____________

A. density of the fluid
B. plastic viscosity
C. volume of liquid to flow
D. specific gravity of fluid
Answer» B. plastic viscosity
298.

The molecular weight of dispersed solids in a colloidal system can be determined using aninstrument:

A. ultracentrifuge
B. ultrafilters
C. ultramicroscope
D. zeta meter
Answer» B. ultrafilters
299.

The physical, chemical, and pharmacologic properties of a drug are directly affected by……

A. Size
B. Surface area
C. Both of the above
D. None of the above
Answer» D. None of the above
300.

The protective ability of colloids is measured as

A. Zeta potential
B. Streaming potential
C. Gold number
D. None of the above
Answer» D. None of the above