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This section includes 925 Mcqs, each offering curated multiple-choice questions to sharpen your GPAT knowledge and support exam preparation. Choose a topic below to get started.
| 251. |
Generally, Stability testing is employed for........... |
| A. | Delivering evidences of the change in quality of the drug product with time. |
| B. | Confirming shelf life for the drug product. |
| C. | Determining container closure system suitability. |
| D. | All of the above |
| Answer» E. | |
| 252. |
High viscosity indicates one of the following relationships in a system. Which is relevant? |
| A. | free from intermolecular interactions |
| B. | intermolecular attractions are stronger |
| C. | intermolecular attractions are weaker |
| D. | shape of the molecules is spherical |
| Answer» C. intermolecular attractions are weaker | |
| 253. |
Silica gel is an example for the type of gel: |
| A. | dilatants |
| B. | elastic |
| C. | rigid |
| D. | thixotropic |
| Answer» D. thixotropic | |
| 254. |
The angle of repose values are utilized to: |
| A. | measure the movement of granules from hopper to the table of tabletting/capsule machine |
| B. | select proper containers for capsules of a given mass of powders |
| C. | study the absorption of drugs |
| D. | understand dissolution of medicament |
| Answer» B. select proper containers for capsules of a given mass of powders | |
| 255. |
........... is the time necessary for the concentration of the reactant to decrease to 90% of its originalconcentration. |
| A. | Product life |
| B. | Shelf life |
| C. | Half life |
| D. | None of the above |
| Answer» C. Half life | |
| 256. |
............ exists when dispersed solid particles in a suspension retain change in relation their adjoiningliquid medium. |
| A. | Surface area |
| B. | Surface potential |
| C. | Surface volume |
| D. | None of the above |
| Answer» C. Surface volume | |
| 257. |
Accelerated stability testing is done to |
| A. | predict shelf of the formulation |
| B. | Predict dissociation constant |
| C. | Predict diffusion constant |
| D. | Determine activation energy |
| Answer» B. Predict dissociation constant | |
| 258. |
Andreasen pipette is widely used method to determine particle size distribution by |
| A. | Microscopy method |
| B. | sedimentation method |
| C. | Sieving method |
| D. | All of the above |
| Answer» C. Sieving method | |
| 259. |
Dilatant flow is characterized as a reverse phenomenon of: |
| A. | newtoniam flow |
| B. | plastic flow |
| C. | pseudoplastic flow |
| D. | rheopexy |
| Answer» D. rheopexy | |
| 260. |
The potential difference develop when particles settle under the influence of gravity is called |
| A. | Streaming potential |
| B. | Oxidation Potential |
| C. | Reduction potential |
| D. | Sedimentation potential |
| Answer» E. | |
| 261. |
The integral rate equation for a reaction (in common notation) is written as log C = log Co - (kt/2.303).When a graph is drawn log c vs. t, the slope will be: |
| A. | negative |
| B. | one |
| C. | Positive |
| D. | Zero |
| Answer» B. one | |
| 262. |
Creaming is a.......... process |
| A. | reversible |
| B. | irreversible |
| C. | A & B |
| D. | difficult to predict |
| Answer» B. irreversible | |
| 263. |
The reaction rate constant (k) is 2.0 x 10-3 min.-1 for aspirin hydrolysis in 0.1 N hydrochloric acid at1mg/ml concentration. Under same conditions, if the product contains aspirin 4 mg/ml of the initial concentration, the k value in minutes-1 will be: |
| A. | 0.5 x l0-3 |
| B. | 2.0 x 10-3 |
| C. | 4.0 x 10-3 |
| D. | 8.0 x 10-3 |
| Answer» C. 4.0 x 10-3 | |
| 264. |
Andreasen apparatus consists of: |
| A. | balance |
| B. | electrodes |
| C. | hydrometer |
| D. | pipette |
| Answer» D. pipette | |
| 265. |
Which one of these preparations is NOT qualified as a suspension. |
| A. | barium meal for radiodiagnostic use |
| B. | calamine lotion for antiseptic use |
| C. | procaine penicillin G for intramuscular injection |
| D. | vitamin B complex tonic as nutritional supplement |
| Answer» E. | |
| 266. |
Suspension is example of |
| A. | Biphasic liquid dosage form |
| B. | Solid dosage form |
| C. | Semi-solid dosage form |
| D. | All of the above |
| Answer» B. Solid dosage form | |
| 267. |
In the equation, Rate = k[C]c[D]d, the order of the above reaction is |
| A. | k |
| B. | C + D |
| C. | [C] *[D] |
| D. | c + d |
| Answer» E. | |
| 268. |
Aerosol is the reverse of : |
| A. | emulsion |
| B. | liquid foam |
| C. | smoke |
| D. | solid foam |
| Answer» C. smoke | |
| 269. |
Dispersion of acacia in water gives the colloid of type: |
| A. | association |
| B. | negative |
| C. | neutral |
| D. | positive |
| Answer» C. neutral | |
| 270. |
The term rheology was invented by |
| A. | Bingham and Crawford |
| B. | Newton |
| C. | Michaelis and Menten |
| D. | Watson and Crick |
| Answer» B. Newton | |
| 271. |
If ions of similar charges involve in reaction it will............rate of reaction. |
| A. | Increases |
| B. | Decreases |
| C. | Remains constant |
| D. | None of the above |
| Answer» C. Remains constant | |
| 272. |
The equal distribution of all the ions in solution retain by…… |
| A. | Electric forces |
| B. | Thermal motion |
| C. | Both of the above |
| D. | None of the above |
| Answer» D. None of the above | |
| 273. |
An emulsifier is considered to be ideal, if it is soluble in |
| A. | Aqueous phase |
| B. | oily phase |
| C. | A & B |
| D. | none of the above |
| Answer» D. none of the above | |
| 274. |
A mixture of span 20 and tween 20 forms....... type of emulsion |
| A. | W/O |
| B. | O/W |
| C. | Milky |
| D. | Hard |
| Answer» B. O/W | |
| 275. |
..........technique is utilized only during determination of order of reaction, when the rate law involvedby only single concentration term. |
| A. | The concentration |
| B. | The half of the concentration |
| C. | The square of the concentration |
| D. | None of the above |
| Answer» D. None of the above | |
| 276. |
Name the type of colloidal dispersion to which electrolytes are normally added in small quantities tostabilize: |
| A. | association |
| B. | lyophilic |
| C. | lyophobic |
| D. | micellar |
| Answer» D. micellar | |
| 277. |
Which one of these methods is the MOST effective in preventing the rate of hydrolysis? |
| A. | buffer |
| B. | complexation |
| C. | removal of water |
| D. | suppression of solubility |
| Answer» D. suppression of solubility | |
| 278. |
Which one of the following properties is applicable to suspensions? |
| A. | Brownian movement |
| B. | laminar flow |
| C. | rapid rate of sedimentation |
| D. | strokes’ law |
| Answer» D. strokes’ law | |
| 279. |
For a flocculated suspension, one of the following criterion is satisfied or established |
| A. | High inter-particle repulsions |
| B. | strong inter-particle attractions |
| C. | weak inter-particle attractions |
| D. | weak inter-particle repulsions |
| Answer» D. weak inter-particle repulsions | |
| 280. |
Addition of alcohol to a hydrophilic colloid leads to: |
| A. | crystallization |
| B. | hydration |
| C. | precipitation |
| D. | stabilization |
| Answer» D. stabilization | |
| 281. |
.... is the number of particles per unit weight. |
| A. | Particle volume |
| B. | Particle number |
| C. | Particle mean |
| D. | Particle weight |
| Answer» C. Particle mean | |
| 282. |
The type of particle diameter that is obtained by microscope method of evaluation is: |
| A. | projected |
| B. | stokes’ |
| C. | volume |
| D. | volume-surface |
| Answer» B. stokes’ | |
| 283. |
An emulsifier can be regarded as superior, if its mechanism of action is based on the principle of: |
| A. | developing solid adsorption film |
| B. | forming monomolecular adsorption film |
| C. | generating multimolecular adsorption film |
| D. | increasing interfacial energy |
| Answer» C. generating multimolecular adsorption film | |
| 284. |
A shear stress-shear rate relationship is generally explained in the form of curve i.e. or……… |
| A. | Rheogram |
| B. | Consistency curve |
| C. | Both of the above |
| D. | None of the above |
| Answer» D. None of the above | |
| 285. |
On commercial scale, emulsions are prepared by:: |
| A. | centrifugation |
| B. | dialysis |
| C. | freezing |
| D. | homogenization |
| Answer» E. | |
| 286. |
The term ‘light’ as applied to pharmaceutical powders means: |
| A. | low bulk density |
| B. | low granule density |
| C. | low true density |
| D. | slightly coloured |
| Answer» C. low true density | |
| 287. |
It is difficult to express the size of particles in a meaningful diameter. |
| A. | irregular in shape |
| B. | irregular surface |
| C. | spherical shape |
| D. | uniform in size |
| Answer» B. irregular surface | |
| 288. |
The distribution of globules is not uniform in an emulsion. This stage is termed as: |
| A. | breaking |
| B. | caking |
| C. | coalescence |
| D. | creaming |
| Answer» E. | |
| 289. |
Which of the following is not a viscometers |
| A. | Capillary |
| B. | Falling Sphere |
| C. | Rotational |
| D. | Drop weight |
| Answer» E. | |
| 290. |
In practice, an acceptable suspension should have particles: |
| A. | of nearly 0.1 micrometer |
| B. | which can be readily re-dispersible after they settle |
| C. | which should form a cake after settling |
| D. | should not settle |
| Answer» C. which should form a cake after settling | |
| 291. |
A zero-order reaction is a reaction having rate of concentration of reactant. |
| A. | Dependent |
| B. | Partially dependent |
| C. | Independent |
| D. | None of the above |
| Answer» D. None of the above | |
| 292. |
In general, Newtonian fluids are expressed in terms of viscosity. A corresponding expression in nonNewtonian fluids (in terms of viscosity) is: |
| A. | apparent |
| B. | dynamic |
| C. | intrinsic |
| D. | kinematic |
| Answer» B. dynamic | |
| 293. |
Regarding the influence of the solvent on the rate of reaction, solvents having the internal pressure: |
| A. | HIGHER produce products with HIGHER internal pressure |
| B. | HIGHER favour the formation of products having LOWER internal pressure |
| C. | LOWER yield products having HIGHER internal pressure |
| D. | LOWER retard the formation of products with LOWER internal pressure |
| Answer» B. HIGHER favour the formation of products having LOWER internal pressure | |
| 294. |
The value of sedimentation volume (F) gives a knowledge about the____________of the suspension |
| A. | physical stability |
| B. | Incompatibility |
| C. | Solubility |
| D. | All of the above |
| Answer» B. Incompatibility | |
| 295. |
Pseudoplastic flow is generally exhibited by |
| A. | Jellies |
| B. | Suspension |
| C. | Lotion |
| D. | Colloids |
| Answer» B. Suspension | |
| 296. |
When charcoal powder is dusted on the surface of water, the contact angle (in degrees) that thecharcoal exhibits is: |
| A. | zero |
| B. | one |
| C. | 90 |
| D. | 180 |
| Answer» E. | |
| 297. |
Kinematic viscosity is the ratio of dynamic viscosity to the____________ |
| A. | density of the fluid |
| B. | plastic viscosity |
| C. | volume of liquid to flow |
| D. | specific gravity of fluid |
| Answer» B. plastic viscosity | |
| 298. |
The molecular weight of dispersed solids in a colloidal system can be determined using aninstrument: |
| A. | ultracentrifuge |
| B. | ultrafilters |
| C. | ultramicroscope |
| D. | zeta meter |
| Answer» B. ultrafilters | |
| 299. |
The physical, chemical, and pharmacologic properties of a drug are directly affected by…… |
| A. | Size |
| B. | Surface area |
| C. | Both of the above |
| D. | None of the above |
| Answer» D. None of the above | |
| 300. |
The protective ability of colloids is measured as |
| A. | Zeta potential |
| B. | Streaming potential |
| C. | Gold number |
| D. | None of the above |
| Answer» D. None of the above | |