Explore topic-wise MCQs in GPAT.

This section includes 925 Mcqs, each offering curated multiple-choice questions to sharpen your GPAT knowledge and support exam preparation. Choose a topic below to get started.

1.

An emulsifier is considered to be ideal, if it is soluble in:

A. aqueous, oil and gas phases
B. aqueous phase only
C. both aqueous and oil phase
D. oil phase only
Answer» D. oil phase only
2.

...........technique is utilized only when the rate law involved by only single concentration term fordetermination of order of reaction.

A. Half Life Method
B. Graphical Method
C. Initial Rate Method
D. Van't Hoff Differential Method
Answer» B. Graphical Method
3.

The pseudoplastic flow behavior can be explained by:

A. apparent viscosity
B. area of hysteresis loop
C. hysteresis loop
D. yield value
Answer» B. area of hysteresis loop
4.

Which one of the following dosage forms exhibit faster rate of reaction under normal conditions?

A. emulsions
B. ointments
C. solutions
D. suspensions
Answer» D. suspensions
5.

The effect of temperature on rate of reaction is explained by

A. Arrhenius equation
B. Nernst equation
C. Noyes Whitney equation
D. Fick's first law
Answer» B. Nernst equation
6.

...... determines the movement of charged particles via a liquid under the impact of anapplied potential difference.

A. Electrophoresis
B. Electrosmosis
C. Surface charge
D. Static movement
Answer» B. Electrosmosis
7.

In reactions that follow first order kinetics, half life is expressed by equation:

A. 0.693/k1
B. 0.301/k1
C. 0.105/k1
D. k1/0.693
Answer» B. 0.301/k1
8.

The true density of talc is 2.7 g/cc, the bulk density (g/cc) of talc will be:

A. equal to 2.7
B. greater than 2.7
C. less than 2.7
D. unrelated
Answer» D. unrelated
9.

Deflocculated suspension with high concentration of the dispersed solids exhibits the flow of type:

A. dilatant
B. newtoniam
C. plastic
D. pseudoplastic
Answer» B. newtoniam
10.

Brookfield viscometer is an example of type:

A. cone and plate
B. extrusion
C. rotation sphere
D. rotating spindle
Answer» E.
11.

ICH stands for

A. Indian council on harmonisation
B. International Conference On Harmonisation
C. Inter Cranial Healer
D. None of the above
Answer» C. Inter Cranial Healer
12.

Emulsions made with tweens are

A. W/O
B. O/W
C. Clear
D. Unstable
Answer» C. Clear
13.

Which of the following is the half life of zero order reaction

A. t1/2 = Ao/2k
B. t1/2 = 0.693/2k
C. t1/2 = Ao/2
D. t1/2 = 2k/ Ao
Answer» B. t1/2 = 0.693/2k
14.

In the preparation of a structured vehicle, which one of the following substances is used?

A. bismuth subnitrate
B. ethyl alcohol
C. glycerin
D. methyl cellulose
Answer» E.
15.

The .......... colloids have strong attraction towards solvents.

A. Lyophilic
B. Lyophobic
C. Associated
D. None of the above
Answer» B. Lyophobic
16.

When distance between the particle are large, the particles experience attractive force and aggregatesare formed. This is known as

A. Primary minimum
B. Potential barrier
C. secondary minimum
D. Interparticle distance
Answer» D. Interparticle distance
17.

The size of dispersed particles in coarse dispersion ranges from

A. 1 µm to 100 µm.
B. 1 nm to l00nm
C. 1mm to 100cm
D. Less than 1 µm
Answer» B. 1 nm to l00nm
18.

The following statement is NOT appropriate for Molecular dispersion

A. Shows tyndall effect
B. Does not scatter light
C. Diffusion rate is rapid
D. Does not settle on ultracentrifugation
Answer» B. Does not scatter light
19.

Fluidity is

A. reciprocal of density
B. reciprocal of surface tension
C. reciprocal of volume
D. reciprocal of viscosity
Answer» E.
20.

The distance between two tangents on opposite sides of the particle parallel to some fixed direction.

A. Feret's diameter
B. Martin diameter
C. Projected diameter
D. Stoke's diameter
Answer» B. Martin diameter
21.

As the temperature increases, the viscosity of liquid...............

A. Decreases
B. Increases
C. Sustainly increases
D. Remains constant
Answer» B. Increases
22.

In stokes’ relationship, a parameter that greatly changes the velocity of settling is:

A. density of the liquid
B. density of particle
C. radius of the particle
D. viscosity of the medium
Answer» D. viscosity of the medium
23.

which of the following is cause of physical degradation of drug?

A. volatilisation of components during storage
B. Changes from one state to another
C. Change in colour
D. All of the above
Answer» E.
24.

Structured vehicle is included in the formulation of a suspension, in order to:

A. decrease the interfacial tension
B. prevent the caking of the sediment
C. prevent the sedimentation of particles
D. reduce the size by chemical me
Answer» B. prevent the caking of the sediment
25.

An o/w microemulsion is prepared using a hydrophilic surfactant. The appearance of themicroemulsion is:

A. intense white
B. milky white
C. translucent
D. tr
Answer» B. milky white
26.

............is the science and technology of small particles.

A. Micromeritics
B. Microscopy
C. Rheology
D. None of the above
Answer» B. Microscopy
27.

Coulter counter is used to determine

A. Particle volume
B. Particle Number
C. Particle interaction
D. Viscosity
Answer» B. Particle Number
28.

The curve for a pseudo plastic material rheogram................

A. starts at the origin
B. starts at the top
C. both of the above
D. none of the above
Answer» B. starts at the top
29.

Which of the following reactions is observed in the degradation of ampicillin?

A. decarboxylation
B. hydrolysis
C. oxidation
D. recimization
Answer» C. oxidation
30.

Creaming in emulsion can be controlled by regulating

A. density of dispersed phase
B. density of dispersion medium
C. globule size
D. volume of dispersion medium
Answer» D. volume of dispersion medium
31.

If kinetic energy of interaction is about 25 kT (Where k is gas constant), the system can be consideredto have:

A. deflocculated state
B. long half life
C. short half life
D. weak attractiton forces
Answer» C. short half life
32.

Homogenous phase (True solution) having size range of

A. 0.5 to 1.0 µm
B. <0.1 nm
C. >0.01 µm
D. <0.01 µm
Answer» E.
33.

Which of the following method/s used for determination of order of reaction?

A. Graphic method
B. Substitution method
C. Half life method
D. All of the above -
Answer» E.
34.

In coulter-counter, as the particles travel through the orifice, the event that occurs is:

A. conductance between the electrodes increases
B. electronic scanners produce photographs for volume measurement
C. resistance between the electrodes increases
D. sedimentation increases
Answer» D. sedimentation increases
35.

According to International Pharmaceutical Federation, the recommended overages be limited to themaximum percent of:

A. five
B. ten
C. thirty
D. twenty
Answer» D. twenty
36.

The half life of a first order reaction is 4 years. What is its shelf life (in years)?

A. 0.02
B. 0.03
C. 0.17
D. 0.61
Answer» E.
37.

In an emulsion, the velocity of sedimentation is found to be negative. It means that the creaming is:

A. absent
B. in both the directions
C. in downward direction
D. in upward direction
Answer» E.
38.

Normally, ethyl acetate undergoes hydrolysis in presence of H+and (OH)-ions. The order of the reaction observed in the acidic and alkaline solutions, respectively, are:

A. first and second
B. pseudo first and second
C. second and first
D. second and pseudo first
Answer» C. second and first
39.

For the formulation of w/o emulsion, the coalescence rate of:

A. w/o has no relationship to the type of emulsion formed
B. o/w is equal to w/o coalescence rate
C. o/w is greater than w/o coalescence rate
D. w/o is greater than the o/w coalescence rate
Answer» D. w/o is greater than the o/w coalescence rate
40.

The phase inversion occur due to

A. changes in type of emulsifying agent
B. change in phase volume ratio.
C. Both a and b
D. None of the above
Answer» D. None of the above
41.

The storage directions on a parenteral solution specify ‘store in a cool place’. This may be stored in:

A. an air-conditioned area at 10°C
B. a refrigerator at 15°C
C. a place whose temperature is set at 5°C
D. room temperature, at 25°C
Answer» C. a place whose temperature is set at 5°C
42.

The cgs physical unit for kinematic viscosity is ...............

A. Stokes (St)
B. Pascale (PS)
C. Newton
D. None of the above
Answer» B. Pascale (PS)
43.

The ratio of the sedimentation volume in case of flocculated suspension to the sedimentation volumein case of deflocculated suspension is called

A. Sedimentation volume
B. Degree of flocculation
C. Emulsification volume
D. phase volume ratio
Answer» C. Emulsification volume
44.

Which of the following properties of a particle significantly affects the physical, chemical andbiological properties of the drug?

A. density
B. sedimentation
C. size
D. surface area
Answer» E.
45.

The following statement is true for Colloidal dispersion

A. Diffusion rate is slow
B. Impermeable across semipermeable membrane
C. Shows tyndall effect
D. All of above
Answer» E.
46.

The criterion to call a system ‘colloid’ is

A. a fine state of subdivision of dispersed phase
B. dispersed particles are in the size range of 1 nm to 1 µm
C. interface is very extensive
D. the presence of dispersed phase in a dispersion medium
Answer» C. interface is very extensive
47.

The unit of activation energy is

A. kJ/mol
B. J
C. N/m
D. mm
Answer» B. J
48.

Which quality of the dispersed phase is responsible for the increased viscosity of a hydrophiliccolloidal dispersion?

A. charge
B. shape
C. size
D. surface area
Answer» E.
49.

Which equation is used to convert number distribution to weight distribution

A. Noyes whitney equation
B. Hatch Choate equation
C. Henderson Hasselbalch equation
D. Higuchi equation
Answer» C. Henderson Hasselbalch equation
50.

Emulsion containing more than two phases are called as

A. Mixed emulsion
B. Multiple emulsion
C. Complex emulsion
D. none of the above
Answer» C. Complex emulsion