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This section includes 925 Mcqs, each offering curated multiple-choice questions to sharpen your GPAT knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
An emulsifier is considered to be ideal, if it is soluble in: |
| A. | aqueous, oil and gas phases |
| B. | aqueous phase only |
| C. | both aqueous and oil phase |
| D. | oil phase only |
| Answer» D. oil phase only | |
| 2. |
...........technique is utilized only when the rate law involved by only single concentration term fordetermination of order of reaction. |
| A. | Half Life Method |
| B. | Graphical Method |
| C. | Initial Rate Method |
| D. | Van't Hoff Differential Method |
| Answer» B. Graphical Method | |
| 3. |
The pseudoplastic flow behavior can be explained by: |
| A. | apparent viscosity |
| B. | area of hysteresis loop |
| C. | hysteresis loop |
| D. | yield value |
| Answer» B. area of hysteresis loop | |
| 4. |
Which one of the following dosage forms exhibit faster rate of reaction under normal conditions? |
| A. | emulsions |
| B. | ointments |
| C. | solutions |
| D. | suspensions |
| Answer» D. suspensions | |
| 5. |
The effect of temperature on rate of reaction is explained by |
| A. | Arrhenius equation |
| B. | Nernst equation |
| C. | Noyes Whitney equation |
| D. | Fick's first law |
| Answer» B. Nernst equation | |
| 6. |
...... determines the movement of charged particles via a liquid under the impact of anapplied potential difference. |
| A. | Electrophoresis |
| B. | Electrosmosis |
| C. | Surface charge |
| D. | Static movement |
| Answer» B. Electrosmosis | |
| 7. |
In reactions that follow first order kinetics, half life is expressed by equation: |
| A. | 0.693/k1 |
| B. | 0.301/k1 |
| C. | 0.105/k1 |
| D. | k1/0.693 |
| Answer» B. 0.301/k1 | |
| 8. |
The true density of talc is 2.7 g/cc, the bulk density (g/cc) of talc will be: |
| A. | equal to 2.7 |
| B. | greater than 2.7 |
| C. | less than 2.7 |
| D. | unrelated |
| Answer» D. unrelated | |
| 9. |
Deflocculated suspension with high concentration of the dispersed solids exhibits the flow of type: |
| A. | dilatant |
| B. | newtoniam |
| C. | plastic |
| D. | pseudoplastic |
| Answer» B. newtoniam | |
| 10. |
Brookfield viscometer is an example of type: |
| A. | cone and plate |
| B. | extrusion |
| C. | rotation sphere |
| D. | rotating spindle |
| Answer» E. | |
| 11. |
ICH stands for |
| A. | Indian council on harmonisation |
| B. | International Conference On Harmonisation |
| C. | Inter Cranial Healer |
| D. | None of the above |
| Answer» C. Inter Cranial Healer | |
| 12. |
Emulsions made with tweens are |
| A. | W/O |
| B. | O/W |
| C. | Clear |
| D. | Unstable |
| Answer» C. Clear | |
| 13. |
Which of the following is the half life of zero order reaction |
| A. | t1/2 = Ao/2k |
| B. | t1/2 = 0.693/2k |
| C. | t1/2 = Ao/2 |
| D. | t1/2 = 2k/ Ao |
| Answer» B. t1/2 = 0.693/2k | |
| 14. |
In the preparation of a structured vehicle, which one of the following substances is used? |
| A. | bismuth subnitrate |
| B. | ethyl alcohol |
| C. | glycerin |
| D. | methyl cellulose |
| Answer» E. | |
| 15. |
The .......... colloids have strong attraction towards solvents. |
| A. | Lyophilic |
| B. | Lyophobic |
| C. | Associated |
| D. | None of the above |
| Answer» B. Lyophobic | |
| 16. |
When distance between the particle are large, the particles experience attractive force and aggregatesare formed. This is known as |
| A. | Primary minimum |
| B. | Potential barrier |
| C. | secondary minimum |
| D. | Interparticle distance |
| Answer» D. Interparticle distance | |
| 17. |
The size of dispersed particles in coarse dispersion ranges from |
| A. | 1 µm to 100 µm. |
| B. | 1 nm to l00nm |
| C. | 1mm to 100cm |
| D. | Less than 1 µm |
| Answer» B. 1 nm to l00nm | |
| 18. |
The following statement is NOT appropriate for Molecular dispersion |
| A. | Shows tyndall effect |
| B. | Does not scatter light |
| C. | Diffusion rate is rapid |
| D. | Does not settle on ultracentrifugation |
| Answer» B. Does not scatter light | |
| 19. |
Fluidity is |
| A. | reciprocal of density |
| B. | reciprocal of surface tension |
| C. | reciprocal of volume |
| D. | reciprocal of viscosity |
| Answer» E. | |
| 20. |
The distance between two tangents on opposite sides of the particle parallel to some fixed direction. |
| A. | Feret's diameter |
| B. | Martin diameter |
| C. | Projected diameter |
| D. | Stoke's diameter |
| Answer» B. Martin diameter | |
| 21. |
As the temperature increases, the viscosity of liquid............... |
| A. | Decreases |
| B. | Increases |
| C. | Sustainly increases |
| D. | Remains constant |
| Answer» B. Increases | |
| 22. |
In stokes’ relationship, a parameter that greatly changes the velocity of settling is: |
| A. | density of the liquid |
| B. | density of particle |
| C. | radius of the particle |
| D. | viscosity of the medium |
| Answer» D. viscosity of the medium | |
| 23. |
which of the following is cause of physical degradation of drug? |
| A. | volatilisation of components during storage |
| B. | Changes from one state to another |
| C. | Change in colour |
| D. | All of the above |
| Answer» E. | |
| 24. |
Structured vehicle is included in the formulation of a suspension, in order to: |
| A. | decrease the interfacial tension |
| B. | prevent the caking of the sediment |
| C. | prevent the sedimentation of particles |
| D. | reduce the size by chemical me |
| Answer» B. prevent the caking of the sediment | |
| 25. |
An o/w microemulsion is prepared using a hydrophilic surfactant. The appearance of themicroemulsion is: |
| A. | intense white |
| B. | milky white |
| C. | translucent |
| D. | tr |
| Answer» B. milky white | |
| 26. |
............is the science and technology of small particles. |
| A. | Micromeritics |
| B. | Microscopy |
| C. | Rheology |
| D. | None of the above |
| Answer» B. Microscopy | |
| 27. |
Coulter counter is used to determine |
| A. | Particle volume |
| B. | Particle Number |
| C. | Particle interaction |
| D. | Viscosity |
| Answer» B. Particle Number | |
| 28. |
The curve for a pseudo plastic material rheogram................ |
| A. | starts at the origin |
| B. | starts at the top |
| C. | both of the above |
| D. | none of the above |
| Answer» B. starts at the top | |
| 29. |
Which of the following reactions is observed in the degradation of ampicillin? |
| A. | decarboxylation |
| B. | hydrolysis |
| C. | oxidation |
| D. | recimization |
| Answer» C. oxidation | |
| 30. |
Creaming in emulsion can be controlled by regulating |
| A. | density of dispersed phase |
| B. | density of dispersion medium |
| C. | globule size |
| D. | volume of dispersion medium |
| Answer» D. volume of dispersion medium | |
| 31. |
If kinetic energy of interaction is about 25 kT (Where k is gas constant), the system can be consideredto have: |
| A. | deflocculated state |
| B. | long half life |
| C. | short half life |
| D. | weak attractiton forces |
| Answer» C. short half life | |
| 32. |
Homogenous phase (True solution) having size range of |
| A. | 0.5 to 1.0 µm |
| B. | <0.1 nm |
| C. | >0.01 µm |
| D. | <0.01 µm |
| Answer» E. | |
| 33. |
Which of the following method/s used for determination of order of reaction? |
| A. | Graphic method |
| B. | Substitution method |
| C. | Half life method |
| D. | All of the above - |
| Answer» E. | |
| 34. |
In coulter-counter, as the particles travel through the orifice, the event that occurs is: |
| A. | conductance between the electrodes increases |
| B. | electronic scanners produce photographs for volume measurement |
| C. | resistance between the electrodes increases |
| D. | sedimentation increases |
| Answer» D. sedimentation increases | |
| 35. |
According to International Pharmaceutical Federation, the recommended overages be limited to themaximum percent of: |
| A. | five |
| B. | ten |
| C. | thirty |
| D. | twenty |
| Answer» D. twenty | |
| 36. |
The half life of a first order reaction is 4 years. What is its shelf life (in years)? |
| A. | 0.02 |
| B. | 0.03 |
| C. | 0.17 |
| D. | 0.61 |
| Answer» E. | |
| 37. |
In an emulsion, the velocity of sedimentation is found to be negative. It means that the creaming is: |
| A. | absent |
| B. | in both the directions |
| C. | in downward direction |
| D. | in upward direction |
| Answer» E. | |
| 38. |
Normally, ethyl acetate undergoes hydrolysis in presence of H+and (OH)-ions. The order of the reaction observed in the acidic and alkaline solutions, respectively, are: |
| A. | first and second |
| B. | pseudo first and second |
| C. | second and first |
| D. | second and pseudo first |
| Answer» C. second and first | |
| 39. |
For the formulation of w/o emulsion, the coalescence rate of: |
| A. | w/o has no relationship to the type of emulsion formed |
| B. | o/w is equal to w/o coalescence rate |
| C. | o/w is greater than w/o coalescence rate |
| D. | w/o is greater than the o/w coalescence rate |
| Answer» D. w/o is greater than the o/w coalescence rate | |
| 40. |
The phase inversion occur due to |
| A. | changes in type of emulsifying agent |
| B. | change in phase volume ratio. |
| C. | Both a and b |
| D. | None of the above |
| Answer» D. None of the above | |
| 41. |
The storage directions on a parenteral solution specify ‘store in a cool place’. This may be stored in: |
| A. | an air-conditioned area at 10°C |
| B. | a refrigerator at 15°C |
| C. | a place whose temperature is set at 5°C |
| D. | room temperature, at 25°C |
| Answer» C. a place whose temperature is set at 5°C | |
| 42. |
The cgs physical unit for kinematic viscosity is ............... |
| A. | Stokes (St) |
| B. | Pascale (PS) |
| C. | Newton |
| D. | None of the above |
| Answer» B. Pascale (PS) | |
| 43. |
The ratio of the sedimentation volume in case of flocculated suspension to the sedimentation volumein case of deflocculated suspension is called |
| A. | Sedimentation volume |
| B. | Degree of flocculation |
| C. | Emulsification volume |
| D. | phase volume ratio |
| Answer» C. Emulsification volume | |
| 44. |
Which of the following properties of a particle significantly affects the physical, chemical andbiological properties of the drug? |
| A. | density |
| B. | sedimentation |
| C. | size |
| D. | surface area |
| Answer» E. | |
| 45. |
The following statement is true for Colloidal dispersion |
| A. | Diffusion rate is slow |
| B. | Impermeable across semipermeable membrane |
| C. | Shows tyndall effect |
| D. | All of above |
| Answer» E. | |
| 46. |
The criterion to call a system ‘colloid’ is |
| A. | a fine state of subdivision of dispersed phase |
| B. | dispersed particles are in the size range of 1 nm to 1 µm |
| C. | interface is very extensive |
| D. | the presence of dispersed phase in a dispersion medium |
| Answer» C. interface is very extensive | |
| 47. |
The unit of activation energy is |
| A. | kJ/mol |
| B. | J |
| C. | N/m |
| D. | mm |
| Answer» B. J | |
| 48. |
Which quality of the dispersed phase is responsible for the increased viscosity of a hydrophiliccolloidal dispersion? |
| A. | charge |
| B. | shape |
| C. | size |
| D. | surface area |
| Answer» E. | |
| 49. |
Which equation is used to convert number distribution to weight distribution |
| A. | Noyes whitney equation |
| B. | Hatch Choate equation |
| C. | Henderson Hasselbalch equation |
| D. | Higuchi equation |
| Answer» C. Henderson Hasselbalch equation | |
| 50. |
Emulsion containing more than two phases are called as |
| A. | Mixed emulsion |
| B. | Multiple emulsion |
| C. | Complex emulsion |
| D. | none of the above |
| Answer» C. Complex emulsion | |