Explore topic-wise MCQs in GPAT.

This section includes 925 Mcqs, each offering curated multiple-choice questions to sharpen your GPAT knowledge and support exam preparation. Choose a topic below to get started.

901.

What is the equation for bioavailability?

A. [AUC]std Dstd τtest / [AUC]test Dtest τstd
B. [AUC]test Dtest τstd / [AUC]std Dstd τtest
C. [AUC]test Dstd τtest / [AUC]std Dtest τstd
D. 1 / [AUC]std Dtest τstd
Answer» D. 1 / [AUC]std Dtest τstd
902.

What kind of substances cannot permeate membranes by passive diffusion?

A. Lipid-soluble
B. Non-ionized substances
C. Hydrophobic substances
D. Hydrophilic substances
Answer» E.
903.

For the calculation of the volume of distribution (Vd) one take into account:

A. Concentration of a substance in urine
B. Concentration of substance in plasma
C. A daily dose of drug
D. Therapeutic width of drug action
Answer» C. A daily dose of drug
904.

In carrier mediated transport energy is derived from……..

A. Hydrolysis of ATP
B. Protein metabolism
C. Concentration gradient
D. All of the above
Answer» B. Protein metabolism
905.

Cell membrane can pass easily Oxygen and Carbon dioxide.

A. False
B. True
C. none
D. all
Answer» C. none
906.

What is the pH range of the intestine?

A. 4-5
B. 1-3
C. 1-8
D. 5-8
Answer» E.
907.

Which of the following promotes excretion of acidic drugs?

A. Citrates
B. Ammonium chloride
C. Methionine
D. Ascorbic acid
Answer» B. Ammonium chloride
908.

What does the graph of Rate of Drug dissolution v/s Compression force with this type of curve interpret?

A. Tight binding of the molecules in drug
B. Deformation of the drug particles into smaller particles
C. The influence of compression force on the dissolution rate is difficult
D. Both tight bonding and deformation of the drug molecules
Answer» B. Deformation of the drug particles into smaller particles
909.

Disease state of a patient can influence drug distribution across the body.

A. True
B. False
C. none
D. all
Answer» B. False
910.

What helps in the passing of inorganic ions?

A. Ion channels
B. Voltage gated channels
C. Aqueous filled pores
D. Diffusion
Answer» D. Diffusion
911.

Which one of the following has a high perfusion rate?

A. Fat
B. Muscle and skin
C. Lungs and kidney
D. Bone
Answer» D. Bone
912.

For a drug that is eliminated primarily by renal glomerular filtration, the theoretical maximumclearance is approximately

A. 1-2 milliliters/min
B. 12 milliliters/min
C. 120 milliliters/min
D. 1200 milliliters/min
Answer» D. 1200 milliliters/min
913.

………..is defined as volume of blood or plasma from drug is removed in unit time

A. half life
B. clearance
C. volume of distribution
D. biotr
Answer» B. clearance
914.

When Km

A. Km – C = C
B. Km + C = C
C. Km + C = Km
D. Km - C = Km
Answer» C. Km + C = Km
915.

Which one of these is not an example of hydrophilic diluents?

A. PVC
B. Dextrose
C. PVP
D. PEG
Answer» B. Dextrose
916.

  Drugs in suspension and semisolid formulations always degrade by -

A. First orer kinetics
B. Second order kinetics
C. Zero order kinetics
D. Non linear kinetics
Answer» D. Non linear kinetics
917.

  Example of market product of soft shell capsule is

A. Phudin hara
B. Seven Seas Capsule
C. Both (Phudin hara) and (Seven Seas Capsule)
D. None
Answer» D. None
918.

  Cascade impactor is used to evaluate :

A. Oral drug delivery system
B. Parenteral drug delivery system
C. Pulmonary drug delivery system
D. None
Answer» D. None
919.

  Consistency of lipstick can be measured by

A. Penetrometer
B. Cup & Bob viscometer
C. Brookfield viscometer
D. All
Answer» B. Cup & Bob viscometer
920.

  Flowability of powder is also expressed as

A. Angle of repose
B. Dustibility
C. Co-efficient of friction
D. All
Answer» E.
921.

  Degradation of suspension follows :

A. First order kinetics
B. Zero order kinetics
C. Non linear kinetics
D. All
Answer» C. Non linear kinetics
922.

  The dissolution media for C.R. dosage form are of gradient pH of

A. 1.2, 4.5, 6.8, 7.2
B. 1.2, 6.8, 7.8
C. 1.2, 7.2, 7.8
D. None
Answer» B. 1.2, 6.8, 7.8
923.

  Sigma blade mixer is commonly used in

A. Wet granulation
B. Dry granulation
C. Powder mixing
D. Crude fiber mixing
Answer» D. Crude fiber mixing
924.

  Delayed release system is:

A. Enteric coated tablets
B. Orally disintegrating tablets
C. Sugar coated tablets
D. None
Answer» B. Orally disintegrating tablets
925.

  Prodrug of Ampicillin is :

A. Naloxane
B. Pirampicillin
C. Chloramphenicol palmitate
D. Cloxacilline
Answer» C. Chloramphenicol palmitate