MCQOPTIONS

Explore topic-wise MCQs in Biotechnology.

This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Biotechnology knowledge and support exam preparation. Choose a topic below to get started.

1.	In the given picture, the marking “b” represents the drug concentration of which compartment?
A.	The central compartment in a two compartment model
B.	The peripheral compartment in a two compartment model
C.	The central compartment in a one compartment model
D.	Drug concentration of the plasma
Answer» C. The central compartment in a one compartment model

2.	In the given picture, the marking “a” represents the drug concentration of which compartment?
A.	The central compartment in a two compartment model
B.	A peripheral compartment in a two compartment model
C.	The central compartment in a one compartment model
D.	Drug concentration of the plasma
Answer» B. A peripheral compartment in a two compartment model

3.	Which of the following is not a category of 2 compartment model?
A.	Two compartment model with elimination from the central compartment
B.	Two compartment model with elimination from the peripheral compartment
C.	Two compartment model with elimination from only plasma and blood
D.	Two compartment model with elimination from both the compartments
Answer» E.

4.	Which organ comprises the peripheral compartment in a two compartment model?
A.	Liver
B.	Lungs
C.	Kidneys
D.	Muscles
Answer» E.

5.	Which organs comprise the central compartment in a two compartment model?
A.	Muscles
B.	Skin
C.	Adipose
D.	Liver
Answer» E.

6.	At which of the four marked points of the plasma drug concentration versus time graph, absorption rate = elimination rate?
A.	a
B.	b
C.	c
D.	d
Answer» B. b

7.	What is the equation to find out hepatic clearance?
A.	Plasma drug concentration/rate of elimination by the kidney
B.	Rate of elimination by kidney/plasma drug concentration
C.	1 / rate of elimination by the kidney
D.	1 / plasma drug concentration
Answer» C. 1 / rate of elimination by the kidney

8.	To have a plasma distribution value of 900 ml and plasma drug concentration to be 1.2 mg/ml what should be the amount of drug that should be given to the patient?
A.	1080 ml
B.	1080 g
C.	1080 mg
D.	1g/ml
Answer» D. 1g/ml

9.	The i.v. bolus dosage is 500mg and the plasma drug concentration is 0.8 mg/ml. What should be the volume of distribution?
A.	625 mg/ml
B.	625 l
C.	625 ml
D.	0.0016 mg/ml
Answer» D. 0.0016 mg/ml

10.	What is the equation to find out the apparent volume of distribution?
A.	Amount of drug in the body/plasma drug concentration
B.	Plasma drug concentration/amount of drug in the body
C.	1 / plasma drug concentration
D.	1 / Amount of drug in the body
Answer» B. Plasma drug concentration/amount of drug in the body

11.	What is meant by elimination half-life?
A.	Time take for half of the amount of drug to get completely eliminated from only the organs
B.	Time take for half of the amount of drug to get completely eliminated from only blood
C.	Time take for half of the amount of drug to get completely eliminated from only plasma
D.	Time take for half of the amount of drug to get completely eliminated from the body as well as plasma
Answer» E.

12.	In the equation log C = log Co – KEt/2.303, what does Co stand for _______
A.	Plasma drug concentration after 60 min of i.v. injection
B.	Plasma drug concentration after 15 min of i.v. injection
C.	Plasma drug concentration after 30 min of i.v. injection
D.	Plasma drug concentration immediately after i.v. injection
Answer» E.

13.	How much time does an intravenously administered drug take to complete a complete circulation?
A.	5-8 min
B.	7-10 min
C.	1-3 min
D.	1 min
Answer» D. 1 min

14.	What does the word “open” mean in the one compartment open model?
A.	The drug easily enters
B.	The drug readily mixes with the blood
C.	Unidirectional input and output
D.	Easy absorption
Answer» D. Easy absorption