Explore topic-wise MCQs in Bioinformatics.

This section includes 12 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

There are two types matrices involved in the study- score matrices and trace matrices.

A. True
B. False
Answer» B. False
Discussion
2.

Which of the following is untrue about Needleman-Wunsch algorithm?

A. It is an example of dynamic programming
B. Basic idea here is to build up the best alignment by using optimal alignments of larger subsequences
C. It was first used by Saul Needleman and Christian Wunsch
D. It was first used in 1970
Answer» C. It was first used by Saul Needleman and Christian Wunsch
Discussion
3.

The number of possible global alignments between two sequences of length N is _____

A. \(\frac{2^N}{\sqrt{πN}}\)
B. \(\frac{2^{2N}}{\sqrt{πN}}\)
C. \(\frac{2^{(N-1)}}{\sqrt{πN}}\)
D. \(\frac{2^{2N}}{\sqrt{N}}\)
Answer» C. \(\frac{2^{(N-1)}}{\sqrt{πN}}\)
Discussion
4.

A dotplot is a visual and qualitative technique whereas the sequence alignment is an exact and quantitative measure of similarity of alignments.

A. True
B. False
Answer» B. False
Discussion
5.

Which_of_the_following_is_untrue_about_Needleman-Wunsch_algorithm?$

A. It is an example of dynamic programming
B. Basic idea here is to build up the best alignment by using optimal alignments of larger subsequences
C. It was first used by Saul Needleman and Christian Wunsch
D. It was first used in 1970
Answer» B. Basic idea here is to build up the best alignment by using optimal alignments of larger subsequences
Discussion
6.

In Needleman-Wunsch algorithm, the gaps are scored -2.

A. True
B. False
Answer» C.
Discussion
7.

Which of the following is untrue about Protein substitution matrices?

A. They are significantly more complex than DNA scoring matrices
B. They have the N x N matrices of the amino acids
C. Protein substitution matrices have quite important role in evolutionary studies
D. They are significantly quite less complex than DNA scoring matrices
Answer» E.
Discussion
8.

The substitution matrices are rarely used in this type of matching.

A. True
B. False
Answer» C.
Discussion
9.

The alignment score is the sum of substitution scores and gap penalties in this type of algorithm.

A. True
B. False
Answer» B. False
Discussion
10.

The global sequence alignment is suitable when the two sequences are of dissimilar length, with a negligible degree of similarity throughout.

A. True
B. False
Answer» C.
Discussion
11.

A dotplot is visual and qualitative technique whereas the sequence alignment is exact and quantitative measure of similarity of alignments.

A. True
B. False
Answer» B. False
Discussion
12.

Which of the following is not the objective to perform sequence comparison?

A. To observe patterns of conservation
B. To find the common motifs present in both sequences
C. To study the physical properties of molecules
D. To study evolutionary relationships
Answer» D. To study evolutionary relationships
Discussion