Explore topic-wise MCQs in Bioinformatics.

This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.

1.

Although MOTIF program is used successfully for making the BLOCKS database, it is limited in the pattern sizes that can be found.

A. True
B. False
Answer» B. False
Discussion
2.

The pattern searching method type of analysis was performed on groups of related proteins, and the amino acid patterns that were located may be found in the Prosite catalog.

A. True
B. False
Answer» B. False
Discussion
3.

The program Profilemake can be used to produce a profile from an MSA.

A. True
B. False
Answer» B. False
Discussion
4.

ALTHOUGH_MOTIF_PROGRAM_IS_USED_SUCCESSFULLY_FOR_MAKING_THE_BLOCKS_DATABASE,_IT_IS_LIMITED_IN_THE_PATTERN_SIZES_THAT_CAN_BE_FOUND.?$

A. True
B. False
Answer» B. False
Discussion
5.

Which_of_the_following_is_not_true_regarding_the_BLOCKS?$

A. The BLOCKS server can extract a conserved, ungapped region from a MSA to produce a sequence block
B. The server can also find blocks in a set of unaligned, input sequences and maintains a large database of blocks based on an analysis of proteins in the Prosite catalog
C. Blocks are found by the Protomat program
D. The program MOTIF doesn’t locate spaced patterns
Answer» E.
Discussion
6.

The pattern searching method type of analysis was performed on groups of related proteins, and the amino acid patterns that were located may be found in the Prosite catalog?

A. True
B. False
Answer» B. False
Discussion
7.

Which of the following is not true regarding the BLOCKS?

A. Blocks of width 10–55 are extracted from a protein MSA
B. The protein MSA is up to 400 sequences
C. The program doesn’t accept manually reformatted MSAs
D. The program accepts FASTA format
Answer» D. The program accepts FASTA format
Discussion
8.

In the method of extraction of blocks from a global or local MSA, a global MSA of related protein sequences usually includes regions that have been aligned without gaps in any of the sequences.

A. True
B. False
Answer» B. False
Discussion
9.

Block analysis methods use substitution matrices such as the PAM and BLOSUM matrices to score matches.

A. True
B. False
Answer» C.
Discussion
10.

Which of the following is untrue regarding the block analysis method?

A. Blocks represent a conserved region in the MSA
B. Blocks differ from profiles in lacking insert and delete positions in the sequences
C. Every column includes only matches and mismatches
D. Blocks may be made by searching for a section of an MSA alignment that is low conserved
Answer» E.
Discussion
11.

The program Profilemake can be used to produce a profile from a MSA

A. True
B. False
Answer» B. False
Discussion
12.

Profiles are found by performing the _____ MSA of a group of sequences and then removing the _______ regions in the alignment into a smaller MSA.

A. local, more highly conserved
B. global, low conserved
C. global, more highly conserved
D. local, low conserved
Answer» D. local, low conserved
Discussion
13.

Which of the following is not among the methods for finding localized sequence similarity?

A. Profile Analysis
B. Block Analysis
C. Extraction of Blocks from a Global or Local MSA
D. Pattern blocking
Answer» E.
Discussion