MCQOPTIONS
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MCQOPTIONS
This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Bioinformatics knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following is not true about iterative methods? |
| A. | Genetic Algorithm is method used for under this |
| B. | Hidden Markov Models are used for Multiple Sequence Alignment |
| C. | The objective is to improve the overall alignment score |
| D. | MultAlin recalculates global scores |
| Answer» E. | |
| 2. |
The HMM is a statistical model that considers few combinations of matches and gaps to generate an alignment of a set of sequences. |
| A. | True |
| B. | False |
| Answer» C. | |
| 3. |
In Genetic Algorithm, in the mutation process _______ |
| A. | sequence is changed |
| B. | gaps are not inserted |
| C. | sequence is not changed |
| D. | gaps are not rearranged |
| Answer» D. gaps are not rearranged | |
| 4. |
The second step in the Genetic Algorithm comprises of scoring of the 100 initial MSAs by the sum of pairs method. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 5. |
The first step in Genetic Algorithm is arranging the sequences to be aligned in rows. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 6. |
An approach for obtaining a higher-scoring MSA (Multiple Sequence Alignment) by rearranging an existing alignment uses a probability approach called simulated annealing. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 7. |
The Genetic Algorithm method has been recently adapted for MSA(Multiple Sequence Alignment) by Corpet (1998). |
| A. | True |
| B. | False |
| Answer» C. | |
| 8. |
In the program DIALIGN, pairs of sequences are aligned to locate aligned regions that do not include gaps, much like continuous diagonals in a dot matrix plot. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 9. |
Which of the following is incorrect regarding PRRP? |
| A. | The program PRRP uses iterative methods to produce an alignment |
| B. | An initial pair-wise alignment is made to predict a tree |
| C. | Only one cycle is performed |
| D. | The whole process is repeated until there is no further increase in the alignment score |
| Answer» D. The whole process is repeated until there is no further increase in the alignment score | |
| 10. |
Iterative methods include repeatedly realigning subgroups of the sequences and then by aligning these subgroups into a local alignment of all of the sequences. |
| A. | True |
| B. | False |
| Answer» C. | |