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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
All are true about estrogen except - |
| A. | Causes cholestasis |
| B. | Used in treatment of gynacomastia |
| C. | Used in HRT |
| D. | Increased risk of breasrt cancer |
| Answer» C. Used in HRT | |
| 2. |
The preffered method of drug designing is: |
| A. | Molecular modeling |
| B. | High throughout method |
| C. | Target-structure based |
| D. | Hit and Trial method |
| Answer» D. Hit and Trial method | |
| 3. |
Drug that inhibitors cell wall synthesis is ? |
| A. | Tetracyclins |
| B. | Penicillins |
| C. | Aminoglycosides |
| D. | Chloramphenicol |
| Answer» C. Aminoglycosides | |
| 4. |
Drug causing Hirsuitism and Gynaecomastia: |
| A. | Penicillin |
| B. | Bumetanide |
| C. | Spironolactone |
| D. | Rifampicin |
| Answer» D. Rifampicin | |
| 5. |
All the following statements are true of diazepam EXCEPT that it - |
| A. | Has high therapeutic index |
| B. | Causes less distortion of sleep architecture |
| C. | Causes microsomal enzyme induction |
| D. | Has lower abuse liability |
| Answer» D. Has lower abuse liability | |
| 6. |
Heart rate is decreased by: |
| A. | Propranolol |
| B. | Isoprenaline |
| C. | Dopamine |
| D. | Dobutamine |
| Answer» B. Isoprenaline | |
| 7. |
Blenomycin toxcity is characterized by destruction of |
| A. | Type I pneumocytes |
| B. | Endothelial cells |
| C. | Alveolar macrophages |
| D. | Type II Pneumocyutes |
| Answer» B. Endothelial cells | |
| 8. |
All of the following drugs are teratogenic except - |
| A. | Alcohol |
| B. | Phenytoin |
| C. | Warfarin |
| D. | Metoclopramide |
| Answer» E. | |
| 9. |
Pulmonary infiltration may be seen with all of the following drugs except: |
| A. | Busulphan |
| B. | Cyclophosphamide |
| C. | 5 FU |
| D. | Bleomycin |
| Answer» D. Bleomycin | |
| 10. |
Which of the following drug influence the splanchnic circulation: |
| A. | Adrenaline |
| B. | Noradrenalin |
| C. | Dopamine |
| D. | Isoprenaline |
| Answer» D. Isoprenaline | |
| 11. |
Megaloblastic anemia is a side-effect of long term therapy with |
| A. | Diazepam |
| B. | INH |
| C. | Phenobarbitone |
| D. | Lithium |
| Answer» D. Lithium | |
| 12. |
Gene therapy has been tried in all EXCEPT |
| A. | Hemophilia |
| B. | Turner's syndrome |
| C. | Phenylketonuria |
| D. | HIV 1 infection |
| Answer» C. Phenylketonuria | |
| 13. |
All of the following drugs are protease inhibitors except: |
| A. | Saquinavir |
| B. | Nelfinavir |
| C. | Ritonavir |
| D. | Abacavir |
| Answer» E. | |
| 14. |
Tianeptine is - |
| A. | 5 HT uptake enhancer |
| B. | GABA inhibitor |
| C. | Norepinephrine reuptake inhibitor |
| D. | MAO inhibitor |
| Answer» B. GABA inhibitor | |
| 15. |
Digoxin toxicity can be precipitated by all except |
| A. | Phenytoin |
| B. | Quinidine |
| C. | Calcium |
| D. | Verapamil |
| Answer» B. Quinidine | |
| 16. |
All of the following are known adverse effects of thalidomide,except: |
| A. | DVT |
| B. | Peripheral Neuropathy |
| C. | Diarrhea |
| D. | Teratogenicity |
| Answer» D. Teratogenicity | |
| 17. |
The most potent stimulator of naive T cells is - |
| A. | B cell |
| B. | Mature dendritic cells |
| C. | Epithelial cells |
| D. | Macrophages |
| Answer» C. Epithelial cells | |
| 18. |
Not a cause of granular contracted kidney - |
| A. | Diabetes mellitus |
| B. | Chronic pyelonephritis |
| C. | Benign nephrosclerosis |
| D. | Chronic glomerulonephritis |
| Answer» B. Chronic pyelonephritis | |
| 19. |
Most common site of myocardial infarction is: |
| A. | Posterior wall of right ventricle |
| B. | Inferior wall of left ventricle |
| C. | Anterior wall of left ventricle |
| D. | Posterior wall of left ventricle |
| Answer» D. Posterior wall of left ventricle | |
| 20. |
Features of malignant hypertension includes all except: |
| A. | Hyperplastic arteriosclerosis |
| B. | Fibrinoid necrosis |
| C. | Necrotizing arteriolitis |
| D. | Hyaline arteriosclerosis |
| Answer» E. | |
| 21. |
Subendothelial electron dense deposits within the glomerulus is seen in - |
| A. | MPGN type I |
| B. | Crescentic glornerulonephritis |
| C. | Dense deposit disease |
| D. | IgA nephropathy |
| Answer» B. Crescentic glornerulonephritis | |
| 22. |
Which of the following is a pan-T lymphocyte marker? |
| A. | CD3 |
| B. | CD2 |
| C. | CD25 |
| D. | CD19 |
| Answer» B. CD2 | |
| 23. |
What is meant by Ca colon stage IIIc. |
| A. | Hepatic metastasis |
| B. | Extension upto serosa and lymph node |
| C. | Extension upto serosa |
| D. | Extension upto mucosa |
| Answer» C. Extension upto serosa | |
| 24. |
Apoptotic bodies are: |
| A. | Pyknotic nucleus without organelles |
| B. | Clumped chromatin bodies |
| C. | No nucleus with organelles |
| D. | Cell membrane bound with organelles |
| Answer» E. | |
| 25. |
The biochemical mechanism of action of digitalis is associated with - |
| A. | A decrease in calcium uptake by the sarcoplasmic reticulum |
| B. | An increase in ATP synthesis |
| C. | An increase in systolic extra cellular calcium levels |
| D. | A block of sodium / calcium exchange |
| Answer» E. | |
| 26. |
NSAIDs causes all except- |
| A. | Papillary necrosis |
| B. | Mesangiocapillary glomerulonephritis |
| C. | Membranous glomerulonephritis |
| D. | Acute hypersensitivity interstitial nephrits |
| Answer» C. Membranous glomerulonephritis | |
| 27. |
A patient taking Ketoconazole and Terfenadine both,is prone for: |
| A. | Cardiac arrhythmia |
| B. | Tixicity of Ketoconazole |
| C. | Congestive cardiac failure |
| D. | All of the above |
| Answer» B. Tixicity of Ketoconazole | |
| 28. |
Chronic thiazide therapy causes persistent hypercalcemia due to: |
| A. | Renal tubular acidosis |
| B. | Fanconi's syndrome |
| C. | Hyper vitaminosis D |
| D. | Hyper parathyroidism |
| Answer» E. | |
| 29. |
Drug of choice of hypertension in pregnancy is - |
| A. | Methyldopa |
| B. | Thiazide |
| C. | Nifedipine |
| D. | Labetolol |
| Answer» B. Thiazide | |
| 30. |
Which one of the following drug causes increased concentration of Naand Cl- in urine with normal bicarbonate: |
| A. | Acetazolamide |
| B. | Bumetanide |
| C. | Ethacrynic acid |
| D. | Frusemide |
| Answer» D. Frusemide | |
| 31. |
Drugs causing after load reduction: |
| A. | Digoxin |
| B. | Captopril |
| C. | Dobutamine |
| D. | Frusemide |
| Answer» C. Dobutamine | |
| 32. |
Lamotrigine has common side effects of - |
| A. | Rash |
| B. | Irritability |
| C. | Nephrotoxicity |
| D. | Behavioral disturbances |
| Answer» E. | |
| 33. |
Dipyridamole acts by: |
| A. | Stimulating PGI2 synthesis |
| B. | Inhibiting PGI2 synthesis |
| C. | Adenosine uptake inhibition |
| D. | Inhibiting thromboxane A2 |
| Answer» D. Inhibiting thromboxane A2 | |
| 34. |
Heparin therapy is monitored by |
| A. | Bleeding time |
| B. | Coagulation time |
| C. | Prothrombin time |
| D. | Partial thromboplastin time |
| Answer» E. | |
| 35. |
A female suffering from psychosis,taking phenothiazines now complains of sudden onset of high grade fever,muscle rigidity and altered sensorium.The diagnosis is: |
| A. | Malignant hyperthermia |
| B. | Neuroleptic malignant syndrome |
| C. | Tardive dyskinesia |
| D. | Akathesia |
| Answer» C. Tardive dyskinesia | |
| 36. |
Which of the following drug is ADP receptor inhibitor ? |
| A. | Aspirin |
| B. | Clopidogrel |
| C. | Abciximab |
| D. | Terutroban |
| Answer» C. Abciximab | |
| 37. |
Pharmocovigilance is used for |
| A. | Monitoring of students |
| B. | Check costs |
| C. | To monitor drug toxicity |
| D. | To monitor unauthorized drug manufacture |
| Answer» D. To monitor unauthorized drug manufacture | |
| 38. |
The appearance of markedly vacuolated, nucleated red cells in the marrow, anemia and reticulocytopenia are characteristic dose dependent side effects of - |
| A. | Azithromycin |
| B. | Chloramphenicol |
| C. | Clindamycin |
| D. | Doxycycline |
| Answer» C. Clindamycin | |
| 39. |
Drug used in prophylaxis of meningococcal meningitis is ? |
| A. | Ciprofloxacin |
| B. | Rifampicin |
| C. | Penicillin |
| D. | Gentamycin |
| Answer» C. Penicillin | |
| 40. |
Ifosfamide belongs to which group of anticancer drugs |
| A. | Mitotic inhibitors |
| B. | Topoisomerase inhibitors |
| C. | Alkylating agents |
| D. | Antiimetobolites |
| Answer» D. Antiimetobolites | |
| 41. |
A 56 year old female presented with breast carcinoma and she was prescribed herceptin(trastuzumab). Which of the following statement regarding the drug is true? |
| A. | It is a monoclonal antibody produced by injecting her-2 antigen |
| B. | It is an antibody produced entirely from mouse containing no human component |
| C. | It is a monoclonal antibody containing only human component |
| D. | It is a polyclonal antibody |
| Answer» B. It is an antibody produced entirely from mouse containing no human component | |
| 42. |
Partial opioid agonist is: |
| A. | Morphine |
| B. | Methadone |
| C. | Buprenorphine |
| D. | Naloxone |
| Answer» D. Naloxone | |
| 43. |
OHA not causing hypoglycemia: |
| A. | Repaglinide |
| B. | Gliclazide |
| C. | Rosiglitazone |
| D. | Glimipiride |
| Answer» D. Glimipiride | |
| 44. |
Drug not used in H. pylori - |
| A. | Omeprezole |
| B. | Metronidazole |
| C. | Amoxicillin |
| D. | Mosapride |
| Answer» E. | |
| 45. |
Tyrosine kinase Inhibitors are used in the treatment of |
| A. | Neurofibromatosis |
| B. | Small cell carcinoma Lung |
| C. | Gastrointestinal stromal tumors (GIST) |
| D. | acute Myeloid Leukemia |
| Answer» D. acute Myeloid Leukemia | |
| 46. |
Photo-sensitivity is a side effect of - |
| A. | Ofloxacin |
| B. | Ciprofloxacin |
| C. | Norfloxacin |
| D. | Pefloxacin |
| Answer» E. | |
| 47. |
Which of the following drugs is to be discontinued on the day of surgery - |
| A. | Amlodipine |
| B. | Atenolol |
| C. | Statins |
| D. | Metformin |
| Answer» E. | |
| 48. |
The group of antibiotics which possess additional anti-inflammatory and immunomodulatory activities is: |
| A. | Fluoroquinolones. |
| B. | Macrolides. |
| C. | Tetracyclines. |
| D. | Polypeptide antibiotics. |
| Answer» C. Tetracyclines. | |
| 49. |
The drug of choice in PSVT is |
| A. | Digoxin |
| B. | Propranolol |
| C. | Lignocaine |
| D. | Adenosine |
| Answer» E. | |
| 50. |
False about protease inhibitors in HIV is - |
| A. | Of all the protease inhibitors saquinavir is the most powerful inhibitor of CYP3A4 |
| B. | They are powerful enzyme inhibitors |
| C. | All protease inhibitors substrates for P glycoprotein coded by MDR gene |
| D. | They cause hepatic toxicity |
| Answer» B. They are powerful enzyme inhibitors | |