Explore topic-wise MCQs in Testing Subject.

This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.

1.

Which of the following is not a hepatotoxic drug

A. Ethambutol
B. Rifampicin
C. INH
D. Cycloserine
Answer» E.
2.

Adrenaline, noradrenaline and dopamine act through ?

A. Two pass receptor
B. Ligand gated channel
C. Seven pass receptor
D. One pass receptor
Answer» D. One pass receptor
3.

Concentration of a drug in blood is 40 micro gm/ml.Dose of the drug is 200mg.Volume of distribution of the drug assuming minute elimination is:

A. 5 litre
B. 0.5 litre
C. 2.5 litre
D. 3 litre
Answer» B. 0.5 litre
4.

Drug not used in treatment of acute asthma is ?

A. Oral prednisolone
B. Inhalational salbutamol
C. Inhalational Salmeterol
D. IV Corticosteroid
Answer» D. IV Corticosteroid
5.

Which of the following causes OCP failure ?

A. Carbamazepine
B. Rifampicin
C. NSAIDS
D. Ethambutol
Answer» C. NSAIDS
6.

Clindamycin acts by inhibiting :

A. Cell wall synthesis
B. Lysosomal enzyme
C. Protein synthesis
D. DNA Gyrase
Answer» D. DNA Gyrase
7.

Drug which does not cause cross BBB ?

A. Hyosinebutylbromide
B. Atropine
C. Glycopyrollate
D. Hyosine hydrobromide
Answer» D. Hyosine hydrobromide
8.

Adverse effects of valproic acid derivatives include the following,Except

A. Weight gain
B. Osteomalacia
C. Alopecia
D. Liver Failure
Answer» C. Alopecia
9.

The drug of choice for thoracic actinomycosis is

A. Amphotericin-B
B. Penicilline
C. Cotrimoxazole
D. Itraconazole
Answer» C. Cotrimoxazole
10.

Dosages adjustment is NOT needed in renal failure in -

A. INH
B. Ethambutol
C. Rifampicin
D. Streptomycin
Answer» D. Streptomycin
11.

Which of the following chemotherapeutic drugs has selective action of hypoxic tumor cells -

A. Mitomycin C
B. Cisplatin
C. Doxorubicin
D. 5 Flurouracil
Answer» B. Cisplatin
12.

SLE reaction is caused by ?

A. Hydralazine
B. Rifampicin
C. Paracetamol
D. Furosemide
Answer» B. Rifampicin
13.

The wrong statement about metronidazole is that it -

A. Is useful in pseudomembranous enterocolitis
B. Is active against aerobic bacteria
C. Is secreted in saliva
D. Can cause disulfiram like intolerance to alcohol
Answer» C. Is secreted in saliva
14.

Chloroquine acts on -

A. Meroxoites
B. Blood schizont
C. Tissue schiont
D. Gametocytes
Answer» C. Tissue schiont
15.

Which one of the following statements about imipenem is most accurate ?

A. The drug has a narrow spectrum of antibacterial action
B. It is used in fixed combination with sublactam
C. Impienem is highly susceptible to beta lactamase produced by enterobacter species
D. In renal dysfunction, dosage reductions are necessary to avoid seizures
Answer» E.
16.

Mannitol is not used in ?

A. Cerebral edema
B. Pulmonary edema
C. Acute congestive glaucoma
D. Threatened acute renal failure
Answer» C. Acute congestive glaucoma
17.

Bisphosphonates are used in all of the following condition except -

A. Steroid induced osteoporosis
B. Post menopausal osteoporosis
C. Malignancy associated Hypercalcemia
D. Hypervitaminosis D
Answer» E.
18.

Febuxostat is used for ?

A. Hyperkalemia
B. Hyperuricemia
C. Hypernatremia
D. Hypercalemia
Answer» C. Hypernatremia
19.

Which drug causes osteporosis on long-term use

A. Estrogen
B. Progesterone
C. GnRH analogues
D. Warfarin
Answer» D. Warfarin
20.

Long-term complications of steroid therapy include all EXCEPT

A. Growth retardation
B. Cataract
C. Potbelly
D. None
Answer» E.
21.

Amphotericin B treatment mandates the monitoring of which of the following electrolytes:

A. Ca2+
B. Na+
C. Mg2+
D. K+
Answer» E.
22.

Which is an antimetabolic -

A. Methotrexate
B. Cyclosporine
C. Vinblastine
D. Etoposide
Answer» B. Cyclosporine
23.

Acute Gouty arthritis is seen early in treatment following -

A. Probenecid
B. Allopurinol
C. Colchicine
D. Rasburicase
Answer» C. Colchicine
24.

L-Dopa is combined with Carbidopa in the treatment of parkinsonism to:

A. Inhibit peripheral decarboxylation of levodopa
B. Decrease the efficacy of levodopa
C. Inhibit conversion of levodopa to dopamine in the CNS
D. Increase the dose of levodopa required
Answer» B. Decrease the efficacy of levodopa
25.

All of the following can cause hemolytic anaemia Except:

A. Isoniazid
B. Rifampicin
C. Co-trimoxazole
D. Propanolol
Answer» E.
26.

Which is prodrug ?

A. Salmeterol
B. Acetazolamide
C. Enalapril
D. Clonidine
Answer» D. Clonidine
27.

Neural tube defect occurs with:

A. Folic acid
B. Valproate
C. Lithium
D. Amiodarone
Answer» C. Lithium
28.

Morphine can be used in all the following conditions except:

A. Hypothyroidism
B. Diabetes
C. Head injury
D. Asthma
Answer» D. Asthma
29.

Drug used for post operative reversal of muscular paralysis -

A. Neostignuine
B. Pyridostigmine
C. Physostigmine
D. D tubocurare
Answer» B. Pyridostigmine
30.

Diagnosis of Myasthenia Gravis is by using:

A. Succinylcholine (SCh)
B. Atropine
C. Edrophonium
D. Neostigmine
Answer» D. Neostigmine
31.

All of the following are used in atrial arrhythmias except -

A. Digoxin
B. Verapamil
C. Quinidine
D. Lignocaine
Answer» E.
32.

Muscle rigidity due to opiods is because of their effect on -

A. sigma
B. delta
C. mu
D. kappa
Answer» D. kappa
33.

Replacement drug for valproate in pregnancy for juvenile myoclonic epilepsy to be given as monotherapy -

A. Carbamazepine
B. Phenytoin
C. Lancosamide
D. Levitiracetam
Answer» E.
34.

Which of the following chemotherapeutic agents is associated with secondary leukemia ?

A. Etoposide
B. Vinblastine
C. Belomycin
D. Cisplatin
Answer» E.
35.

Drug of choice for pneumocystis carinii -

A. Cotriamoxazole
B. Erythromycin
C. Penicillin
D. Metronidazole
Answer» B. Erythromycin
36.

The drug NOT used for analgesia in a head injury patient is:

A. Morphine
B. NSAIDS
C. Rofecoxib
D. Acetaminofen
Answer» B. NSAIDS
37.

Drug used in uncomplicated alcohol withdrawal ?

A. Propanalol
B. Methadone
C. Diazepam
D. Clonidine
Answer» D. Clonidine
38.

GnRH agonist used as nasal spray in the treatment of endometriosis:

A. Leuprolide
B. Gonadorelin
C. Nafarelin
D. Histrelin
Answer» D. Histrelin
39.

Which of the following drugs is associated with untoward side effect of renal tubular inhibitor ?

A. Methysergide
B. Cyclophosphamide
C. Cisplatin
D. Steptozotocin
Answer» D. Steptozotocin
40.

Histopathology of mitral valve prolapsed shows what kind of change ?

A. Myxomatous
B. Fibrinoid
C. Granulomatous
D. Fibrous
Answer» B. Fibrinoid
41.

Which one of the following is used in therapy of toxoplasmosis?

A. Ciprofloxacin.
B. Pyrimethamine.
C. Artensenuate.
D. Thiacetazone.
Answer» C. Artensenuate.
42.

Drug that can be hypertrophic pyloric stenosis ?

A. Tertacyclin
B. Erythromycin
C. Ampicillin
D. Rifampicin
Answer» C. Ampicillin
43.

Most common dose limiting toxicity of chemotherapeutic agent ?

A. Neurotoxicity
B. Alopecia
C. Myelosuppression
D. G.I. toxicity
Answer» D. G.I. toxicity
44.

In India all drugs are given under supervised regimen except ?

A. Pyrazinamide
B. Rifampicin
C. Dapsone
D. Clofazimine
Answer» D. Clofazimine
45.

All of the following are GpIIb/IIIa antagonist except:

A. Abciximab
B. Clopidogrel
C. Tirofiban
D. Epitifibatide
Answer» C. Tirofiban
46.

Loop diuretics such as furosemide act by -

A. Decreasing tubular reabsorption of NA+ and increase GFR
B. Decreasing H+ secretion with resultant increase in NA+ and K+ excretion
C. Inhibiting NA+ NA+ - K+ -2Cl - contransporter in the medullary thick ascending limb
D. Inhibiting NA+ - K+ exchange in the collecting duct
Answer» D. Inhibiting NA+ - K+ exchange in the collecting duct
47.

Drug of choice in Acute central anticholinergic syndrome is

A. Physostigmine
B. Neostigmine
C. 4-amino pyridine
D. Tacrine
Answer» B. Neostigmine
48.

Loading dose depends on -

A. Rate of administration
B. Half life
C. Volume of distribution
D. Clearance
Answer» D. Clearance
49.

Which of the following agents is not associated with Hyperthermia

A. Atropine
B. Alcohol
C. Amphetamines
D. MAO inhibitors
Answer» C. Amphetamines
50.

A middle aged old man,with chronic renal failure is diagnosed to have sputum-positive pulmonary tuberculosis.His creatinine clearance is 25ml/min.All of the following drugs need modification in doses except:

A. Isoniazide
B. Streptomycin
C. Rifampicin
D. Ethambutol
Answer» D. Ethambutol