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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following is not a hepatotoxic drug |
| A. | Ethambutol |
| B. | Rifampicin |
| C. | INH |
| D. | Cycloserine |
| Answer» E. | |
| 2. |
Adrenaline, noradrenaline and dopamine act through ? |
| A. | Two pass receptor |
| B. | Ligand gated channel |
| C. | Seven pass receptor |
| D. | One pass receptor |
| Answer» D. One pass receptor | |
| 3. |
Concentration of a drug in blood is 40 micro gm/ml.Dose of the drug is 200mg.Volume of distribution of the drug assuming minute elimination is: |
| A. | 5 litre |
| B. | 0.5 litre |
| C. | 2.5 litre |
| D. | 3 litre |
| Answer» B. 0.5 litre | |
| 4. |
Drug not used in treatment of acute asthma is ? |
| A. | Oral prednisolone |
| B. | Inhalational salbutamol |
| C. | Inhalational Salmeterol |
| D. | IV Corticosteroid |
| Answer» D. IV Corticosteroid | |
| 5. |
Which of the following causes OCP failure ? |
| A. | Carbamazepine |
| B. | Rifampicin |
| C. | NSAIDS |
| D. | Ethambutol |
| Answer» C. NSAIDS | |
| 6. |
Clindamycin acts by inhibiting : |
| A. | Cell wall synthesis |
| B. | Lysosomal enzyme |
| C. | Protein synthesis |
| D. | DNA Gyrase |
| Answer» D. DNA Gyrase | |
| 7. |
Drug which does not cause cross BBB ? |
| A. | Hyosinebutylbromide |
| B. | Atropine |
| C. | Glycopyrollate |
| D. | Hyosine hydrobromide |
| Answer» D. Hyosine hydrobromide | |
| 8. |
Adverse effects of valproic acid derivatives include the following,Except |
| A. | Weight gain |
| B. | Osteomalacia |
| C. | Alopecia |
| D. | Liver Failure |
| Answer» C. Alopecia | |
| 9. |
The drug of choice for thoracic actinomycosis is |
| A. | Amphotericin-B |
| B. | Penicilline |
| C. | Cotrimoxazole |
| D. | Itraconazole |
| Answer» C. Cotrimoxazole | |
| 10. |
Dosages adjustment is NOT needed in renal failure in - |
| A. | INH |
| B. | Ethambutol |
| C. | Rifampicin |
| D. | Streptomycin |
| Answer» D. Streptomycin | |
| 11. |
Which of the following chemotherapeutic drugs has selective action of hypoxic tumor cells - |
| A. | Mitomycin C |
| B. | Cisplatin |
| C. | Doxorubicin |
| D. | 5 Flurouracil |
| Answer» B. Cisplatin | |
| 12. |
SLE reaction is caused by ? |
| A. | Hydralazine |
| B. | Rifampicin |
| C. | Paracetamol |
| D. | Furosemide |
| Answer» B. Rifampicin | |
| 13. |
The wrong statement about metronidazole is that it - |
| A. | Is useful in pseudomembranous enterocolitis |
| B. | Is active against aerobic bacteria |
| C. | Is secreted in saliva |
| D. | Can cause disulfiram like intolerance to alcohol |
| Answer» C. Is secreted in saliva | |
| 14. |
Chloroquine acts on - |
| A. | Meroxoites |
| B. | Blood schizont |
| C. | Tissue schiont |
| D. | Gametocytes |
| Answer» C. Tissue schiont | |
| 15. |
Which one of the following statements about imipenem is most accurate ? |
| A. | The drug has a narrow spectrum of antibacterial action |
| B. | It is used in fixed combination with sublactam |
| C. | Impienem is highly susceptible to beta lactamase produced by enterobacter species |
| D. | In renal dysfunction, dosage reductions are necessary to avoid seizures |
| Answer» E. | |
| 16. |
Mannitol is not used in ? |
| A. | Cerebral edema |
| B. | Pulmonary edema |
| C. | Acute congestive glaucoma |
| D. | Threatened acute renal failure |
| Answer» C. Acute congestive glaucoma | |
| 17. |
Bisphosphonates are used in all of the following condition except - |
| A. | Steroid induced osteoporosis |
| B. | Post menopausal osteoporosis |
| C. | Malignancy associated Hypercalcemia |
| D. | Hypervitaminosis D |
| Answer» E. | |
| 18. |
Febuxostat is used for ? |
| A. | Hyperkalemia |
| B. | Hyperuricemia |
| C. | Hypernatremia |
| D. | Hypercalemia |
| Answer» C. Hypernatremia | |
| 19. |
Which drug causes osteporosis on long-term use |
| A. | Estrogen |
| B. | Progesterone |
| C. | GnRH analogues |
| D. | Warfarin |
| Answer» D. Warfarin | |
| 20. |
Long-term complications of steroid therapy include all EXCEPT |
| A. | Growth retardation |
| B. | Cataract |
| C. | Potbelly |
| D. | None |
| Answer» E. | |
| 21. |
Amphotericin B treatment mandates the monitoring of which of the following electrolytes: |
| A. | Ca2+ |
| B. | Na+ |
| C. | Mg2+ |
| D. | K+ |
| Answer» E. | |
| 22. |
Which is an antimetabolic - |
| A. | Methotrexate |
| B. | Cyclosporine |
| C. | Vinblastine |
| D. | Etoposide |
| Answer» B. Cyclosporine | |
| 23. |
Acute Gouty arthritis is seen early in treatment following - |
| A. | Probenecid |
| B. | Allopurinol |
| C. | Colchicine |
| D. | Rasburicase |
| Answer» C. Colchicine | |
| 24. |
L-Dopa is combined with Carbidopa in the treatment of parkinsonism to: |
| A. | Inhibit peripheral decarboxylation of levodopa |
| B. | Decrease the efficacy of levodopa |
| C. | Inhibit conversion of levodopa to dopamine in the CNS |
| D. | Increase the dose of levodopa required |
| Answer» B. Decrease the efficacy of levodopa | |
| 25. |
All of the following can cause hemolytic anaemia Except: |
| A. | Isoniazid |
| B. | Rifampicin |
| C. | Co-trimoxazole |
| D. | Propanolol |
| Answer» E. | |
| 26. |
Which is prodrug ? |
| A. | Salmeterol |
| B. | Acetazolamide |
| C. | Enalapril |
| D. | Clonidine |
| Answer» D. Clonidine | |
| 27. |
Neural tube defect occurs with: |
| A. | Folic acid |
| B. | Valproate |
| C. | Lithium |
| D. | Amiodarone |
| Answer» C. Lithium | |
| 28. |
Morphine can be used in all the following conditions except: |
| A. | Hypothyroidism |
| B. | Diabetes |
| C. | Head injury |
| D. | Asthma |
| Answer» D. Asthma | |
| 29. |
Drug used for post operative reversal of muscular paralysis - |
| A. | Neostignuine |
| B. | Pyridostigmine |
| C. | Physostigmine |
| D. | D tubocurare |
| Answer» B. Pyridostigmine | |
| 30. |
Diagnosis of Myasthenia Gravis is by using: |
| A. | Succinylcholine (SCh) |
| B. | Atropine |
| C. | Edrophonium |
| D. | Neostigmine |
| Answer» D. Neostigmine | |
| 31. |
All of the following are used in atrial arrhythmias except - |
| A. | Digoxin |
| B. | Verapamil |
| C. | Quinidine |
| D. | Lignocaine |
| Answer» E. | |
| 32. |
Muscle rigidity due to opiods is because of their effect on - |
| A. | sigma |
| B. | delta |
| C. | mu |
| D. | kappa |
| Answer» D. kappa | |
| 33. |
Replacement drug for valproate in pregnancy for juvenile myoclonic epilepsy to be given as monotherapy - |
| A. | Carbamazepine |
| B. | Phenytoin |
| C. | Lancosamide |
| D. | Levitiracetam |
| Answer» E. | |
| 34. |
Which of the following chemotherapeutic agents is associated with secondary leukemia ? |
| A. | Etoposide |
| B. | Vinblastine |
| C. | Belomycin |
| D. | Cisplatin |
| Answer» E. | |
| 35. |
Drug of choice for pneumocystis carinii - |
| A. | Cotriamoxazole |
| B. | Erythromycin |
| C. | Penicillin |
| D. | Metronidazole |
| Answer» B. Erythromycin | |
| 36. |
The drug NOT used for analgesia in a head injury patient is: |
| A. | Morphine |
| B. | NSAIDS |
| C. | Rofecoxib |
| D. | Acetaminofen |
| Answer» B. NSAIDS | |
| 37. |
Drug used in uncomplicated alcohol withdrawal ? |
| A. | Propanalol |
| B. | Methadone |
| C. | Diazepam |
| D. | Clonidine |
| Answer» D. Clonidine | |
| 38. |
GnRH agonist used as nasal spray in the treatment of endometriosis: |
| A. | Leuprolide |
| B. | Gonadorelin |
| C. | Nafarelin |
| D. | Histrelin |
| Answer» D. Histrelin | |
| 39. |
Which of the following drugs is associated with untoward side effect of renal tubular inhibitor ? |
| A. | Methysergide |
| B. | Cyclophosphamide |
| C. | Cisplatin |
| D. | Steptozotocin |
| Answer» D. Steptozotocin | |
| 40. |
Histopathology of mitral valve prolapsed shows what kind of change ? |
| A. | Myxomatous |
| B. | Fibrinoid |
| C. | Granulomatous |
| D. | Fibrous |
| Answer» B. Fibrinoid | |
| 41. |
Which one of the following is used in therapy of toxoplasmosis? |
| A. | Ciprofloxacin. |
| B. | Pyrimethamine. |
| C. | Artensenuate. |
| D. | Thiacetazone. |
| Answer» C. Artensenuate. | |
| 42. |
Drug that can be hypertrophic pyloric stenosis ? |
| A. | Tertacyclin |
| B. | Erythromycin |
| C. | Ampicillin |
| D. | Rifampicin |
| Answer» C. Ampicillin | |
| 43. |
Most common dose limiting toxicity of chemotherapeutic agent ? |
| A. | Neurotoxicity |
| B. | Alopecia |
| C. | Myelosuppression |
| D. | G.I. toxicity |
| Answer» D. G.I. toxicity | |
| 44. |
In India all drugs are given under supervised regimen except ? |
| A. | Pyrazinamide |
| B. | Rifampicin |
| C. | Dapsone |
| D. | Clofazimine |
| Answer» D. Clofazimine | |
| 45. |
All of the following are GpIIb/IIIa antagonist except: |
| A. | Abciximab |
| B. | Clopidogrel |
| C. | Tirofiban |
| D. | Epitifibatide |
| Answer» C. Tirofiban | |
| 46. |
Loop diuretics such as furosemide act by - |
| A. | Decreasing tubular reabsorption of NA+ and increase GFR |
| B. | Decreasing H+ secretion with resultant increase in NA+ and K+ excretion |
| C. | Inhibiting NA+ NA+ - K+ -2Cl - contransporter in the medullary thick ascending limb |
| D. | Inhibiting NA+ - K+ exchange in the collecting duct |
| Answer» D. Inhibiting NA+ - K+ exchange in the collecting duct | |
| 47. |
Drug of choice in Acute central anticholinergic syndrome is |
| A. | Physostigmine |
| B. | Neostigmine |
| C. | 4-amino pyridine |
| D. | Tacrine |
| Answer» B. Neostigmine | |
| 48. |
Loading dose depends on - |
| A. | Rate of administration |
| B. | Half life |
| C. | Volume of distribution |
| D. | Clearance |
| Answer» D. Clearance | |
| 49. |
Which of the following agents is not associated with Hyperthermia |
| A. | Atropine |
| B. | Alcohol |
| C. | Amphetamines |
| D. | MAO inhibitors |
| Answer» C. Amphetamines | |
| 50. |
A middle aged old man,with chronic renal failure is diagnosed to have sputum-positive pulmonary tuberculosis.His creatinine clearance is 25ml/min.All of the following drugs need modification in doses except: |
| A. | Isoniazide |
| B. | Streptomycin |
| C. | Rifampicin |
| D. | Ethambutol |
| Answer» D. Ethambutol | |