MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The following drugs are useful in the treatment of isoniazid poisoning - |
| A. | Pyridoxine |
| B. | Diazepam |
| C. | Bicarbonate |
| D. | All of the above |
| Answer» E. | |
| 2. |
The WRONG statement of sumatriptan is that it - |
| A. | Is a selective 5-HT ID/IB receptor agonist |
| B. | Is safe for use in patients with epilepsy |
| C. | Suppresses neurogenic inflammation of cranial blood vessels |
| D. | Is useful in the treatment of an acute attack of migraine |
| Answer» C. Suppresses neurogenic inflammation of cranial blood vessels | |
| 3. |
The effects of adenosine are potentiated in patients receiving dipyridamole because - |
| A. | Dipyridamole is an adenosine uptake inhibitor |
| B. | Dipyridamole is an adenosine receptor blocker |
| C. | Dipyridamole is an adenosine receptor agonist |
| D. | Dipyridamole is an adenosine deaminase activator |
| Answer» B. Dipyridamole is an adenosine receptor blocker | |
| 4. |
Which of the following is a naturally occurring opioid ? |
| A. | Pentaxocine |
| B. | Heroin |
| C. | Fentanyl |
| D. | Morphine |
| Answer» E. | |
| 5. |
Administration of which drug may lead to neuropsychiatric symptoms - |
| A. | Cycloserine |
| B. | Ethionamide |
| C. | Rifampicin |
| D. | Cephalosporins |
| Answer» C. Rifampicin | |
| 6. |
Which of the following statements regarding adenosine is not true: |
| A. | Has short lived side effects |
| B. | Disopyramidase increases its therapeutic effect |
| C. | Used in PSVT |
| D. | Administered as rapid I.V. infection |
| Answer» C. Used in PSVT | |
| 7. |
Which one of the statements is false regarding adefovir dipivoxil - |
| A. | Acyclic nucleotide analogue |
| B. | Well tolerated orally |
| C. | Used in chronic hepatitic C infection |
| D. | Used in anti retroviral therapy |
| Answer» D. Used in anti retroviral therapy | |
| 8. |
'First-pass effect' is seen with which route of administration |
| A. | Oral |
| B. | Sublingual |
| C. | Intramuscular |
| D. | Intravenous |
| Answer» B. Sublingual | |
| 9. |
Which of the following traditional medicines is effective in the treatment of heart failure - |
| A. | Terminalia Arjuna |
| B. | Neem bark extract |
| C. | St. John's wort |
| D. | Gingkoba biloba |
| Answer» B. Neem bark extract | |
| 10. |
All of the following statements about adverse effects of tetracyclines are true Except: |
| A. | May precipitate Liver damage |
| B. | Are not known to be teratogenic |
| C. | May lead to discolouration of teeth |
| D. | Are a common cause of Superinfections |
| Answer» C. May lead to discolouration of teeth | |
| 11. |
Which is not an effect of atropine ? |
| A. | Rise of body temperature |
| B. | Decreased salivery secretion |
| C. | Bradycardia |
| D. | Increased A-V conduction |
| Answer» D. Increased A-V conduction | |
| 12. |
Sodium 2-mercapto ethane sulfonate(mesna)is used as a protective agent in |
| A. | Radiotherapy |
| B. | Cancer chemotherapy |
| C. | Lithotripsy |
| D. | Hepatic encephalopathy |
| Answer» C. Lithotripsy | |
| 13. |
Ksparing diuretic: |
| A. | Thiazides |
| B. | Ethacrynic acid |
| C. | Acetazolamide |
| D. | Amiloride |
| Answer» E. | |
| 14. |
Long post antibiotic effect is seen in ? |
| A. | Quinolones |
| B. | Macrolides |
| C. | Penicillin |
| D. | Cephalosporin |
| Answer» B. Macrolides | |
| 15. |
Verapamil is used in all, except - |
| A. | Angina pectoris |
| B. | Atrial fibrillation |
| C. | Ventricular tachycardia |
| D. | None of the above |
| Answer» D. None of the above | |
| 16. |
The mechanism of action of sodium nitroprusside is: |
| A. | Increased guanylate cyclase |
| B. | Increased cAMP |
| C. | K+ channel opener |
| D. | Calcium channel blockage |
| Answer» B. Increased cAMP | |
| 17. |
The classic karyotype of Klinefelter syndrome is - |
| A. | 47XXY |
| B. | 45XO |
| C. | 48XXY |
| D. | 46XY/47XXY |
| Answer» B. 45XO | |
| 18. |
Dilantin causes ? |
| A. | Folic acid deficiency |
| B. | Thiamine deficiency |
| C. | Nicotinamide deficiency |
| D. | Riboflavin deficiency |
| Answer» B. Thiamine deficiency | |
| 19. |
Pulmonary fibrosis is a side effect of - |
| A. | Methotrexate |
| B. | Vincristine |
| C. | Bleomycin |
| D. | Cyclophophamide |
| Answer» D. Cyclophophamide | |
| 20. |
The following are true of fluoroquinolones except |
| A. | Low toxicity to host cells |
| B. | DNA-gyrase inhibitors |
| C. | Effective against Pseudomonas |
| D. | Rapidly develop resistance |
| Answer» E. | |
| 21. |
All of the following drugs can cause neuroleptic malignant syndrome exept |
| A. | Domperidone |
| B. | Amantadine |
| C. | Metoclopramide |
| D. | Haloperidol |
| Answer» B. Amantadine | |
| 22. |
All of the statements are true about FLUORO QUINOLONES,except: |
| A. | Increase theophylline toxicity |
| B. | Increase neuromuscular blocking action |
| C. | Suspected of having teratogenic potential |
| D. | Arthropathy of limb-in children may occur |
| Answer» C. Suspected of having teratogenic potential | |
| 23. |
Pulmonary fibrosis is the most common complication after treatment with |
| A. | 6-mercaptopurine |
| B. | Vincristine |
| C. | Bleomycine |
| D. | Adriamycine |
| Answer» D. Adriamycine | |
| 24. |
OCP should not be used with - |
| A. | Streptomycin |
| B. | Pyrazinamide |
| C. | Rifampicin |
| D. | INH |
| Answer» D. INH | |
| 25. |
Due to which side effect felbamate can be discontinued ? |
| A. | Aplastic anemia |
| B. | Renal impairment |
| C. | Gastrointestinal disorder |
| D. | Seizures |
| Answer» B. Renal impairment | |
| 26. |
Regarding milrinone, all are true, EXCEPT - |
| A. | Thrombocytopenia is rare |
| B. | Phosphodiesterase 3 inhibitor |
| C. | Antiarrhythmic action |
| D. | Given for long duration |
| Answer» D. Given for long duration | |
| 27. |
All of the following statements are true about theophylline except: |
| A. | Increase in dose is required in smokers |
| B. | Inhibits phosphodiesterase |
| C. | Increase in dose is required in cardiopulmonary disease |
| D. | Increases cAMP |
| Answer» D. Increases cAMP | |
| 28. |
Which of following is true regarding recent guidelines of WTO in relation to international drug trade: |
| A. | Import of generic drugs by developing countries |
| B. | Supply of drugs for diseases like HIV,malaria at low price to developing countries |
| C. | Patent of drugs to be given to multinational companies only |
| D. | All of the above |
| Answer» C. Patent of drugs to be given to multinational companies only | |
| 29. |
Antiplatelet therapy with clopidogrel is usually given for patients with stroke,myocardial infraction and peripheral vascular diseases.Proton pump inhibitors are usually administered along with clopidogrel to prevent the risk of increased gastrointestinal erosion and bleeding.The interaction between clopidogrel and PPI has recently been given much attention due to its clinical significance.Which of the following enzymes is the common pathway of metabolism of both drugs that plays an important role in their interaction. |
| A. | CYP3A4 |
| B. | CYP2D6 |
| C. | CYP2C19 |
| D. | CYP2C9 |
| Answer» D. CYP2C9 | |
| 30. |
Expanded spectrum betalactam resistance drug used |
| A. | Cefepime |
| B. | Amoxicillin-clavulinic acid |
| C. | Ceftriaxone |
| D. | Piperacillin-Tazobactam |
| Answer» B. Amoxicillin-clavulinic acid | |
| 31. |
Amongst the following,least glucocorticoid activity is seen with |
| A. | Fludrocortisone |
| B. | Dexamethasone |
| C. | Triamcinolone |
| D. | Betamethasone |
| Answer» D. Betamethasone | |
| 32. |
Therapeutic index is a measure ? |
| A. | Efficacy |
| B. | Adverse effects |
| C. | Safety |
| D. | Potency |
| Answer» D. Potency | |
| 33. |
Gemcitabine is effective in: |
| A. | Pancreatic cancer |
| B. | Head and neck cancers |
| C. | Soft tissue sarcoma |
| D. | Small-cell lung cancer |
| Answer» B. Head and neck cancers | |
| 34. |
ACE inhibitors are contraindicated in all of the following EXCEPT |
| A. | Pregnancy |
| B. | Diabetes |
| C. | Bilateral renal artery stenosis |
| D. | Renal failure |
| Answer» C. Bilateral renal artery stenosis | |
| 35. |
All of the following antiepileptic agents act via Nachannel except |
| A. | Vigabatrin |
| B. | Phenytoin |
| C. | Valproate |
| D. | Lamotrigne |
| Answer» B. Phenytoin | |
| 36. |
A 60-year old hypertensive patient on Angiotensin II receptor antagonists (losartan) is posed for hernia repair surgery.The antihypertensive drug should be- |
| A. | Continued till the day of operation |
| B. | Discontinued 24 hrs preoperatively |
| C. | Discontinued one week preoperatively |
| D. | Administered in an increased dosage on the day of operation |
| Answer» B. Discontinued 24 hrs preoperatively | |
| 37. |
Type A (Augmented) adverse drug reactions are characterized by all except - |
| A. | Qualitatively abnormal response to the drug |
| B. | Predictable from the drug's known pharmacological or toxicological effects |
| C. | Generally dose dependent |
| D. | Usually common |
| Answer» B. Predictable from the drug's known pharmacological or toxicological effects | |
| 38. |
Side-effects of Captopril are all except |
| A. | Cough |
| B. | Hyperkalemia |
| C. | Renal dysfunction |
| D. | Hemolytic anemia |
| Answer» E. | |
| 39. |
Pancreatitis occurs with: |
| A. | Lamivudine |
| B. | Didanosine |
| C. | Abacavir |
| D. | Zidovudine |
| Answer» C. Abacavir | |
| 40. |
Thaliomide is used in all except |
| A. | HIV neuropathy |
| B. | ENL |
| C. | Behcet's syndrome |
| D. | HIV associated ulcer |
| Answer» B. ENL | |
| 41. |
Maximum amount of Photosensitivity is seen with: |
| A. | Ofloxacin |
| B. | Ciprofloxacin |
| C. | Norfloxacin |
| D. | Pefloxacin |
| Answer» E. | |
| 42. |
Drug of choice for prophylaxis in diptheria is: |
| A. | Tetracycline |
| B. | Clindamycin |
| C. | Erythromycin |
| D. | Doxycicline |
| Answer» D. Doxycicline | |
| 43. |
Antifungal used as cancer chemo therapeutic agent is ? |
| A. | Flucytosine |
| B. | Nystatin |
| C. | Vorconazole |
| D. | Terbinafine |
| Answer» B. Nystatin | |
| 44. |
Adverse effect of phenytoin include the following except: |
| A. | Lymphadenopathy |
| B. | Ataxia |
| C. | Hypercalcemia |
| D. | Hirsutism |
| Answer» D. Hirsutism | |
| 45. |
A child has phocomelia.This is due to drug taken by mother- |
| A. | Thalidomide |
| B. | Tetracycline |
| C. | Chloroquine |
| D. | Warfarin |
| Answer» B. Tetracycline | |
| 46. |
All are true about immunosuppressants except? |
| A. | Tacrolimus inhibits calcineurin pathway |
| B. | Steroids binds to cytosolic receptors and heat shock proteins |
| C. | Mycophenolate inhibit purine synthesis via GMP dehydrogenase |
| D. | Sirolimus will block kinase in the IL 2 receptor pathway |
| Answer» D. Sirolimus will block kinase in the IL 2 receptor pathway | |
| 47. |
All are true about sitagliptin except - |
| A. | Always given with insulin |
| B. | Preferentially reduce post prandial blood sugar |
| C. | Less side effect |
| D. | Lowers HbA1 C |
| Answer» B. Preferentially reduce post prandial blood sugar | |
| 48. |
Which of the following has the shortest plasma half-life |
| A. | Propranolol |
| B. | Esmolol |
| C. | Timolol |
| D. | Atenolol |
| Answer» C. Timolol | |
| 49. |
An idiopathic epileptic patient is on phenytoin and tricyclic antidepressent.He becomes easily fatigue and lethargy.His Hb 8.2 gm%,TLC 9600 cmm.Serum bilirubin 0.6,SGPT 25 IU/lit.The next investigation done is: |
| A. | MCV |
| B. | Gamma glutamy transferase assay |
| C. | Chest X-ray |
| D. | Urine culture |
| Answer» B. Gamma glutamy transferase assay | |
| 50. |
Use of Tamoxifen for Breast cancer can cause all of the following adverse effects,Except. |
| A. | Endometrial carcinoma |
| B. | Thromboembolism |
| C. | Cataract |
| D. | Carcinoma in contralateral breast |
| Answer» E. | |