MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
True about calvulonic acid is ? |
| A. | Beta lactamase inhibitors |
| B. | Extended spectrum penicillin |
| C. | Gram negative bacteria |
| D. | Plasmid inhibitors |
| Answer» B. Extended spectrum penicillin | |
| 2. |
Ipratropium bromide is contraindicated in: |
| A. | Urinary retention |
| B. | Asthma |
| C. | Peptic ulcer |
| D. | Hypertension |
| Answer» B. Asthma | |
| 3. |
Which of the following is the most characteristic feature of Adult Respiratory Distress Syndrome(ARDS): |
| A. | Surfactant Deficiency |
| B. | Hypocapnia |
| C. | Diffuse Alveolar Damage |
| D. | Hypoxemia and Hypoxia |
| Answer» D. Hypoxemia and Hypoxia | |
| 4. |
Which of the following is the most characteristic ultrastructural feature of paraganglioma on electron microscopy |
| A. | Frequent mitoses |
| B. | Dense core neuroendocrine granules |
| C. | Shrunken mitochondria |
| D. | Large Golgi apparatus |
| Answer» C. Shrunken mitochondria | |
| 5. |
In an ablated animal, myeloid series cells are injected.Which of the following is seen after incubation period - |
| A. | RBC |
| B. | Fibroblast |
| C. | T lypphocytes |
| D. | Hematopoetic stem cell |
| Answer» B. Fibroblast | |
| 6. |
Characteristic pathological feature of Parkinson's disease is presence of: |
| A. | Neuro fibrillary tangle |
| B. | Negri-bodies |
| C. | Lewy bodies |
| D. | Babes nodule |
| Answer» D. Babes nodule | |
| 7. |
Lady 30 years painless supraclavicular Lymph node enlargement Growth (+). Has CD 15 and CD 30 positive diagnosis is - |
| A. | Nodular Sclerosis |
| B. | Lymphocyte Pre Dominant |
| C. | Diffuse Large B-cell Lymphoma |
| D. | Lymphocyte Depleted |
| Answer» B. Lymphocyte Pre Dominant | |
| 8. |
N-MYC amplification is associated with which tumor ? |
| A. | Burkitt lymphoma |
| B. | Squamous cell carcinoma lung |
| C. | Astrocytoma |
| D. | Neuroblastoma |
| Answer» E. | |
| 9. |
Which characteristic feature is seen in the kidney in Malignant hypertension |
| A. | Hyaline necrosis |
| B. | Fibrinoid necrosis |
| C. | Medial wall hyperplasia |
| D. | Micro-aneurysm |
| Answer» C. Medial wall hyperplasia | |
| 10. |
Ferruginous bodies are seen in ? |
| A. | Sarcoidosis |
| B. | Silicosis |
| C. | Asbestosis |
| D. | Coal worker's pneumoconiosis |
| Answer» C. Asbestosis | |
| 11. |
In Alzheimer's disease the likely site of lesion is the: |
| A. | Basal ganglia |
| B. | Parital lobes of cerebrum |
| C. | Basal nucleus of Mayernet |
| D. | Pons |
| Answer» D. Pons | |
| 12. |
Factor present in the final common terminal complement pathway is: |
| A. | C4 |
| B. | C3 |
| C. | C5 |
| D. | Protein B |
| Answer» D. Protein B | |
| 13. |
Why fetal cells continue to divide but terminally differentiated adult cells do not divide - |
| A. | Proteinase is absen in fetus |
| B. | Absence of CD kinase |
| C. | There are many cyclin inhibitors which prevent cell to enter into S phase in adult |
| D. | Phosphatase absent in fetal cells |
| Answer» D. Phosphatase absent in fetal cells | |
| 14. |
A patient with HB-6 gm, TLC 12000, PLATELET - 60000, MCV 12FL, what is the diagnosis - |
| A. | Megaloblastic anemia |
| B. | Aplastic anemia |
| C. | Myelofibrosis |
| D. | PNH |
| Answer» B. Aplastic anemia | |
| 15. |
Inflammatory bowel disease with transmural and skip lesions is ? |
| A. | Corhn's disease |
| B. | Ulcerative colitis |
| C. | Shigella infection |
| D. | Clostridium infection |
| Answer» B. Ulcerative colitis | |
| 16. |
In acute inflammation due to contraction of endothelial cell cytoskeleton, which of the following results - |
| A. | Ealry transient increase |
| B. | Delayed transient increase in permeability |
| C. | Ealry permanenet increase |
| D. | Delayed permanenet increase |
| Answer» B. Delayed transient increase in permeability | |
| 17. |
In post-hepatic jaundice,the concentation of conjugated bilirubin in the blood is higher than that of unconjugated bilirubin because: |
| A. | There is an increased rate of destruction of red blood cells |
| B. | The unconjugated bilirubin is trapped by the bile stone produced in the bile duct |
| C. | The conjugation process of bilirubin in liver remains operative without any interference |
| D. | The UDP-glulcuronoyltransferase activity is increased manifold in obstructive jaundice |
| Answer» D. The UDP-glulcuronoyltransferase activity is increased manifold in obstructive jaundice | |
| 18. |
Firm warty vegetations along the line of apposition of heart valves is present in - |
| A. | NBTE |
| B. | Bacterial endocarditis |
| C. | Rheumatic heart disease |
| D. | Libman Sach's endocarditis |
| Answer» D. Libman Sach's endocarditis | |
| 19. |
Amongst the following,the most common site for Leiomyoma is |
| A. | Stomach |
| B. | Small Intestine |
| C. | Duodenum |
| D. | Colon |
| Answer» B. Small Intestine | |
| 20. |
Drugs which produce gynecomastia are all except - |
| A. | Cimetedine |
| B. | Digoxin |
| C. | Cortisol |
| D. | Spironolactone |
| Answer» D. Spironolactone | |
| 21. |
Filgrastim is used in treatment of: |
| A. | Anemia |
| B. | Neutropenia |
| C. | Malaria |
| D. | Filaria |
| Answer» C. Malaria | |
| 22. |
Test for myasthenia gravis is |
| A. | Succinylcholine |
| B. | Edrophonium |
| C. | Atracurium |
| D. | d-Tubocurarine |
| Answer» C. Atracurium | |
| 23. |
All are used in prophylaxis of migraine except: |
| A. | Propranolol |
| B. | Sodium valproate |
| C. | Clonidine |
| D. | Sumatriptan |
| Answer» E. | |
| 24. |
All of the following statements regarding bioavailability of a drug are true except: |
| A. | Bioavailability of an orally administered drug can be calculated by comparing the Area Under Curve (o-alpha) after oral and intravenous (IV) administration |
| B. | It is the proportion (fraction) of unchanged drug that reaches the systemic circulation |
| C. | Bioavailability can be determined from plasma concentration or urinary excretion data |
| D. | Low oral bioavailability always and necessarily mean poor absorption |
| Answer» E. | |
| 25. |
ADH acts on |
| A. | Proximal convoluted tubule |
| B. | Distal convoluted tubule |
| C. | Loop of Henle |
| D. | Collecting ducts |
| Answer» E. | |
| 26. |
The antithyroid drug preferred for use during pregnancy and lactation is - |
| A. | Propylthiouracil |
| B. | Methimazole |
| C. | Carbimazole |
| D. | Radioactive iodine |
| Answer» B. Methimazole | |
| 27. |
What is true about Lovastatin -` |
| A. | Inhibits HMG CoA synthesis |
| B. | Inhibits HMG CoA reductase |
| C. | Myositis may result from its prolonged use |
| D. | Decrease synthesis of cholesterol and causes lenticular opacity |
| Answer» C. Myositis may result from its prolonged use | |
| 28. |
All the following drugs are reversible inhibitors of COX except - |
| A. | Diclofenac |
| B. | Ibuprofen |
| C. | Aspirin |
| D. | Indomethacin |
| Answer» D. Indomethacin | |
| 29. |
Nephrotoxicity is a side effect of one of the following immuno-suppressives - |
| A. | Sirolimus |
| B. | Tacrolimus |
| C. | Mycophenolate mofetil |
| D. | Azathioprine |
| Answer» C. Mycophenolate mofetil | |
| 30. |
Quinidine is a : |
| A. | Ca++ channel-blocker |
| B. | Cl- channel-blocker |
| C. | Na+ channel-blocker |
| D. | K+ channel-blocker |
| Answer» D. K+ channel-blocker | |
| 31. |
Alkalinization of urine is done during administration of which of the following chemotherapeutic drugs: |
| A. | Methotrexate |
| B. | Ara-C |
| C. | Ifosafamide |
| D. | Cisplatin |
| Answer» B. Ara-C | |
| 32. |
Frusemide causes all except: |
| A. | Hyperglycemia |
| B. | Hypomagnesemia |
| C. | Hypokalemia |
| D. | Acidosis |
| Answer» E. | |
| 33. |
Drug which increases Nitrix Oxide are all except - |
| A. | Sodium Nitroprusside |
| B. | Fenoldopam |
| C. | Glycerine trinitrate |
| D. | Hydralazine |
| Answer» C. Glycerine trinitrate | |
| 34. |
Lid retraction caused by - |
| A. | Apraclonidine |
| B. | Brimonidine |
| C. | Latanoprost |
| D. | Travaprost |
| Answer» B. Brimonidine | |
| 35. |
All the following are Selective Estrogen Receptor Modulators(SERMs) except - |
| A. | Clomiphene citrate |
| B. | Tamoxifen citrate |
| C. | Raloxifene |
| D. | Ormeloxifene |
| Answer» B. Tamoxifen citrate | |
| 36. |
Antagonist of Benzodiazepine is - |
| A. | Nalorphine |
| B. | Carbamazepine |
| C. | Naloxone |
| D. | Flumazenil |
| Answer» E. | |
| 37. |
Drug administered sublingually due to increased hepatic first pass metabolism: |
| A. | Stanozolol |
| B. | Tamoxifen |
| C. | Diethyl stilbestrol |
| D. | Natural oestrogen |
| Answer» B. Tamoxifen | |
| 38. |
The drug of choice for bacterial vaginosis is |
| A. | Doxycycline |
| B. | Metronidazole |
| C. | Penicillin |
| D. | Fluconazole |
| Answer» C. Penicillin | |
| 39. |
Gynaecomastia may be associated with administration of: |
| A. | Cimetidine |
| B. | Ranitidine |
| C. | Omeprazole |
| D. | Terfenadine |
| Answer» B. Ranitidine | |
| 40. |
Beta blocker that can be used in renal failure is all except: |
| A. | Pindolol |
| B. | Propranolol |
| C. | Oxyprenolol |
| D. | Sotalol |
| Answer» E. | |
| 41. |
Drug causing hypercoagulability is: |
| A. | L asparginase |
| B. | Busulfan |
| C. | Melphalan |
| D. | 5 FU |
| Answer» B. Busulfan | |
| 42. |
The drug inactivated in plasma by spontaneous non-enzymatic degradation is - |
| A. | Atracurium |
| B. | Vecuronium |
| C. | Pipecuronium |
| D. | Pancuronium |
| Answer» B. Vecuronium | |
| 43. |
A patient presents with nephrotic syndrome and hypoalbuminemia.Protein binding of which drug is not affected: |
| A. | Tolbutamide |
| B. | Morphine |
| C. | Diazepam |
| D. | Valproate |
| Answer» C. Diazepam | |
| 44. |
The mechanism of action of local anesthetics is that they act on Na+channels in their: |
| A. | Activated state |
| B. | Inactivated state |
| C. | Resting state |
| D. | Any state |
| Answer» C. Resting state | |
| 45. |
Which of the following does NOT reduce preload on heart - |
| A. | Glyceryl trinitrate |
| B. | Isosorbid dinitrate |
| C. | ACE inhibitor |
| D. | Hydralazine |
| Answer» E. | |
| 46. |
Saquinavir acts as an anti-HIV agent by acting as: |
| A. | Reverse transcriptase inhibitor |
| B. | Inhibitis CD4 + cell proliferation |
| C. | Inhibit binding of virus particle to cell |
| D. | Protease inhibitor |
| Answer» E. | |
| 47. |
Which of the following statements about Mycophenolate Mofetil is not true |
| A. | It is a prodrug and converted to Mycophenolic acid |
| B. | Is not used with Azathioprine |
| C. | Most common adverse effect is Nephrotoxicity |
| D. | Used in Transplant Rejection |
| Answer» D. Used in Transplant Rejection | |
| 48. |
FK-506 is a - |
| A. | Non depolarising muscle relaxant |
| B. | Opioid analgesic |
| C. | It is a macrolide antibiotic |
| D. | Immunoglobulin antibody |
| Answer» D. Immunoglobulin antibody | |
| 49. |
DENOSUMBA a monoclonal antibody against RANKL receptor is used in treatment of - |
| A. | Osteoarthritis |
| B. | Rheumatoid arthritis |
| C. | SLE |
| D. | Osteoporosis |
| Answer» E. | |
| 50. |
Bone marrow aplasia is seen with all except - |
| A. | Alpha methyl hydantoin |
| B. | Phenylbutazone |
| C. | Methicillin |
| D. | Chloramphenicol |
| Answer» D. Chloramphenicol | |