MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In which of the following disease is corticosteroids indicated ? |
| A. | Osteoporosis |
| B. | Peptic ulcer |
| C. | Collagen disease |
| D. | Tuberculosis |
| Answer» D. Tuberculosis | |
| 2. |
A drug 'A' is already in use and drug 'B' needs to be introduced.The value of the new drug in relation to the old drug can be established by which phase of drug trial. |
| A. | Phase II |
| B. | Phase I |
| C. | Phase IV |
| D. | Phase III |
| Answer» E. | |
| 3. |
Which one of the following drugs is used in absence seizures ? |
| A. | Phenobarbitone |
| B. | Phenytoin |
| C. | Valproate |
| D. | Carbamazepine |
| Answer» D. Carbamazepine | |
| 4. |
A patient is having benign prostatic hyperplasia.He is having a blood pressure of 180/110mmHg and a serum Creatinine of 3.5.Which of the following drugs is NOT to be used to treat him: |
| A. | Prazosin |
| B. | Enlapril |
| C. | Amlodepine |
| D. | Metoprolol |
| Answer» C. Amlodepine | |
| 5. |
Which of the following antitubercular drugs does not cause hepatotoxicity ? |
| A. | Isoniazid |
| B. | Ethambutol |
| C. | Pyrazinamide |
| D. | Rifampicin |
| Answer» C. Pyrazinamide | |
| 6. |
A patient with diarrhea was prescribed a drug to inhibit pyruvate ferrodoxime oxidoreductase.which of the following infections is he likely to be suffering from: |
| A. | Trepanosomiasis |
| B. | Whip worm infection |
| C. | Cryptosporidiasis |
| D. | Beef tape worm infection |
| Answer» D. Beef tape worm infection | |
| 7. |
All of the following drugs are used as immunosuppressants |
| A. | Cyclosporin |
| B. | Glucocorticoids |
| C. | Azathioprine |
| D. | Cephalosporin |
| Answer» E. | |
| 8. |
Therapeutic index of a drug is an indicator of its |
| A. | Potency |
| B. | Safety |
| C. | Toxicity |
| D. | Efficacy |
| Answer» C. Toxicity | |
| 9. |
The most potent drug to reduce plasma cholesterol level is |
| A. | Plant sterols |
| B. | Fibrates |
| C. | Anion exchange resins |
| D. | Statins |
| Answer» E. | |
| 10. |
Selegilline is a selective inhibitor of: |
| A. | MAO-B |
| B. | MAO-A |
| C. | Norepinephrine-uptake |
| D. | Dopamine |
| Answer» B. MAO-A | |
| 11. |
Patients suffering from multidrug resistant tuberculosis can be treated with all of the following drugs except: |
| A. | Ciprofloxacin |
| B. | Clarithromycin |
| C. | Tobramycin |
| D. | Amikacin |
| Answer» D. Amikacin | |
| 12. |
The level of LDL cholesterol at which therapy should be initiated in a patient without coronary artery disease and no risk factor is |
| A. | 100 mg/dL |
| B. | 130 mg/dL |
| C. | 160 mg/dL |
| D. | 190 mg/dL |
| Answer» E. | |
| 13. |
In treatment of shock Dobutamine is preferred over dopamine because ? |
| A. | It causes less arrhythmia |
| B. | It causes less renal vasodilatation |
| C. | It causes less coronary vasoconstriction |
| D. | All of the avove |
| Answer» E. | |
| 14. |
Following drugs except one are effective on topical application in the treatment of wide angle glaucoma - |
| A. | Betaxolol |
| B. | Dipivefrin |
| C. | Latanoprost |
| D. | Acetazolamide |
| Answer» E. | |
| 15. |
A 30 yrs old manic patient was prescribed haloperidol one week back.For last two days he has become restless and kept pacin in the room for a day.On examination he was fond to have tremors of hand.He is most likely suffering from: |
| A. | Anhedonia |
| B. | Dystonia |
| C. | Restless leg syndrome |
| D. | Akathisia |
| Answer» E. | |
| 16. |
Prazosin is used in the preoperative preparation of: |
| A. | Phaeochromocytoma |
| B. | Cushing's disease |
| C. | Thyrotoxicosis |
| D. | Testicular seminoma |
| Answer» B. Cushing's disease | |
| 17. |
All of the following are true about competitive inhibitor except: |
| A. | Reduces potency |
| B. | Maximum level is not reached by increasing the concentration of the drug |
| C. | Resembles chemically with the agonist |
| D. | Bind the same receptors |
| Answer» C. Resembles chemically with the agonist | |
| 18. |
Which of the following is an aromatase inhibitor ? |
| A. | Letrozole |
| B. | Tamoxifen |
| C. | Taxane |
| D. | Danazol |
| Answer» B. Tamoxifen | |
| 19. |
Which of the following is an example of endogenous/Physiological Antagonism ? |
| A. | Heparin-Protamine |
| B. | Prostacycline-Thrombaxone |
| C. | Adrenaline-Phenoxybezamine |
| D. | Physiostigmine-Acetylcholine |
| Answer» C. Adrenaline-Phenoxybezamine | |
| 20. |
Pancytopenia with a cellular marrow is seen in all except - |
| A. | Myelodysplastic syndrome |
| B. | Congenital dyserythropoietic anemia |
| C. | PNH |
| D. | Megaloblastic anemia |
| Answer» C. PNH | |
| 21. |
Shock lung is characterized by ? |
| A. | Diffuse pulmonary hemorrhage |
| B. | Diffuse alveolar damage |
| C. | Alveolar proteinosis |
| D. | Bronchiolitis obliterans |
| Answer» C. Alveolar proteinosis | |
| 22. |
D.I.C. is seen in - |
| A. | CMC |
| B. | Autoimmune hemolytic anemia |
| C. | Acute promyelocytic leukemia |
| D. | Acute myelomonocytic leukemia |
| Answer» D. Acute myelomonocytic leukemia | |
| 23. |
Common pathological changes seen in kidney in benign hypertension are : |
| A. | Microaneurysm |
| B. | Fibronoid necrosis |
| C. | Thining of walls |
| D. | Hyaline arteriosclerosis |
| Answer» E. | |
| 24. |
Reinke's crystals are found in - |
| A. | Arrhenoblastoma |
| B. | Granulosa cell tumor |
| C. | Dysgerminoma |
| D. | Hilus cell tumor |
| Answer» E. | |
| 25. |
Efavirenz acts on - |
| A. | HIV 1 PROTEASE |
| B. | HIV 1 reverse transcriptase |
| C. | HIV 1 integrase |
| D. | HIV entry into cell |
| Answer» C. HIV 1 integrase | |
| 26. |
Wire loop lesions are seen in: |
| A. | Wegner's granulomatosis |
| B. | Polyarteritis nodosa |
| C. | SLE |
| D. | Diabetic nephropathy |
| Answer» D. Diabetic nephropathy | |
| 27. |
Nestritide is a : |
| A. | Brain natriuretic peptide analogue |
| B. | Endothelin R antagonist |
| C. | Gp IIb/ IIIa antagonist |
| D. | TNF alpha antagonist |
| Answer» B. Endothelin R antagonist | |
| 28. |
Which of the following drugs is not used in Acute Angle closure Glaucoma |
| A. | Clozapine |
| B. | Pilocarpine |
| C. | Duloxetine |
| D. | Fluphenazine |
| Answer» B. Pilocarpine | |
| 29. |
Selective 5-HT reuptake blocker is - |
| A. | Desipramine |
| B. | Amitryptiline |
| C. | Fluoxetine |
| D. | Dothiepin |
| Answer» D. Dothiepin | |
| 30. |
Statin induced myopathy is NOT exacerbated by which of the following drugs: |
| A. | Nicotinic acid |
| B. | Enalapril |
| C. | Erythromycin |
| D. | Clofibrate |
| Answer» C. Erythromycin | |
| 31. |
All of the following enzymes and their reactions are involved in the metabolism of Xenobiotics,Except |
| A. | Methylation |
| B. | Hydroxylation |
| C. | Cytochrome oxidase |
| D. | Cytochrome p 450 |
| Answer» D. Cytochrome p 450 | |
| 32. |
A patient suffering from HIV infection is put on HAART therapy.He presents to the outpatient department with lipodystrophy.Laboratory investigations show hypertriglyceredemia and hypercholesterolemia.Which of the following agents is most likely responsible: |
| A. | Ritonavir |
| B. | Zidovudine |
| C. | Lamivudine |
| D. | Nevirapine |
| Answer» B. Zidovudine | |
| 33. |
What is the mode of action of Sodium Cromoglycate - |
| A. | Mast cell stabilization |
| B. | Antihistaminic |
| C. | Anticholinergic |
| D. | None of the above |
| Answer» B. Antihistaminic | |
| 34. |
Which anti-hypertensive drug is avoided in pregnancy ? |
| A. | Enalapril |
| B. | Labetalol |
| C. | Sodium nitropruside |
| D. | Methyldopa |
| Answer» B. Labetalol | |
| 35. |
A diabetic patient developed cellulitis due to staphylococcus aureus, Which was found to be Methicillin resistant on the antibiotic sensitivity testing.All the following antibiotics will be appropriate except: |
| A. | Imipenem |
| B. | Vancomycin |
| C. | Linezoiid |
| D. | Teichoplanin |
| Answer» B. Vancomycin | |
| 36. |
In Equivalent concentrations,steroids are more potent in which form: |
| A. | Cream |
| B. | Gel |
| C. | Lotion |
| D. | Ointment |
| Answer» E. | |
| 37. |
Which one of the following drugs increases gastro-intestinal motility? |
| A. | Antropine. |
| B. | Glycopyrrolate. |
| C. | Fentanyl. |
| D. | Neostigmine. |
| Answer» E. | |
| 38. |
A 50 year old man had an attack of myocardial infarction and developed ventricular ectopics and low ejection fraction.Which of the following antiarrhythmic drug to be given: |
| A. | Flecainide |
| B. | Mexilitine |
| C. | Beta-blocker |
| D. | Radio-frequency ablation technique |
| Answer» D. Radio-frequency ablation technique | |
| 39. |
Which of the following oncogenes is a growth factor? |
| A. | jun |
| B. | sis |
| C. | fos |
| D. | myc |
| Answer» C. fos | |
| 40. |
Neointimal hyperplasia causes vascular graft failure as a result of hypertrophy of: |
| A. | Collagen fibers |
| B. | Endothelial cells |
| C. | Elastic fibers |
| D. | Smooth muscle cells |
| Answer» E. | |
| 41. |
Tetrazoopermia refers to ? |
| A. | Absence of semen |
| B. | Absence of sperm |
| C. | All dead sperms in ejaculate |
| D. | Morphologically defective sperms |
| Answer» E. | |
| 42. |
An albino girl gets married to a normal boy.What are the chances of their having an affected child and what are the chances of their children being carriers? |
| A. | 50% carriers |
| B. | 50% affected,50% carriers |
| C. | None affected,all carriers |
| D. | All normal |
| Answer» D. All normal | |
| 43. |
Which type of Amyloidosis is caused by mutation of the transthyretin protein? |
| A. | Familial amyloidotic polyneuropathy. |
| B. | Familial Mediterranean fever. |
| C. | Prion protein associated amyloidosis. |
| D. | Dialysis associated amyloidosis. |
| Answer» B. Familial Mediterranean fever. | |
| 44. |
Two siblings with osteogenesis imperfect, but their parents are normal.Mechanism of inheritance is- |
| A. | Genomic imprinting |
| B. | Anticipation |
| C. | New mutation |
| D. | Germ line mosaicism |
| Answer» E. | |
| 45. |
The drug imatinib acts by inhibition of - |
| A. | Thymidile synthetase |
| B. | Protein kinase |
| C. | Tyrosine kinase |
| D. | Glutathione reductase |
| Answer» D. Glutathione reductase | |
| 46. |
The most common site for myocardial infarction is |
| A. | Left atrium |
| B. | Left ventricle |
| C. | Right atrium |
| D. | Right ventricle |
| Answer» C. Right atrium | |
| 47. |
Clofazimine therapy causes: |
| A. | Hemolytic anaemia |
| B. | Pigmentation of skin |
| C. | Agranulocytosis |
| D. | Methemoglobinemia |
| Answer» C. Agranulocytosis | |
| 48. |
What is the mechanism of acute rheumatic fever - |
| A. | Due to toxin secretion by streptococci |
| B. | Release of pyrogenic cytokines |
| C. | Cross reactivity with endogenous antigen |
| D. | Innocent by slender effect |
| Answer» D. Innocent by slender effect | |
| 49. |
Which is NOT a component of Werner's syndrome |
| A. | Pituitary |
| B. | Adrenal |
| C. | Parathyroid |
| D. | Pancreas |
| Answer» C. Parathyroid | |
| 50. |
All of the following are reversible anticholinesterases except |
| A. | Physostigmine |
| B. | Ambenonium |
| C. | Pyridostigmine |
| D. | Echothiophate |
| Answer» E. | |