MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Imatinib is used in the treatment of ? |
| A. | ALL |
| B. | GIST |
| C. | Chronic myelomonocytic leukemia |
| D. | MDS |
| Answer» D. MDS | |
| 2. |
One of the following is prodrug: |
| A. | Alpha methyldopa |
| B. | Captopril |
| C. | Propranolol |
| D. | Prazosin |
| Answer» B. Captopril | |
| 3. |
Clinically significant drug interaction occurs between pyridoxine and all of the following drugs except: |
| A. | Cyclosporine |
| B. | Isoniazid |
| C. | Hydralazine |
| D. | Levodopa |
| Answer» B. Isoniazid | |
| 4. |
All these drugs except one cross the blood brain barrier - |
| A. | Morphine |
| B. | Dopamine |
| C. | Propranolol |
| D. | Ether |
| Answer» C. Propranolol | |
| 5. |
Mechanism of action of quinolones is ? |
| A. | DNA gyrase inhibitors |
| B. | Bind to 30 s unit |
| C. | Bind to bacterial cell membrane |
| D. | Bind to tetrahydofolate reductase |
| Answer» B. Bind to 30 s unit | |
| 6. |
One of the potential microsomal inhibitors drug is |
| A. | Phenobarbitone |
| B. | Griseofulvin |
| C. | Sodium valproate |
| D. | Phenytoin |
| Answer» D. Phenytoin | |
| 7. |
All the following antibiotics act on the cell wall except |
| A. | Ampicillin |
| B. | Bacitracin |
| C. | Cycloserine |
| D. | Griseofulvin |
| Answer» E. | |
| 8. |
Which antipsychotic has partial agonist action of both D2 and 5HT1A ? |
| A. | Risperidone |
| B. | Olanzapine |
| C. | Clozapine |
| D. | Aripiprazole |
| Answer» E. | |
| 9. |
A patient with Ewing's sarcoma.Histology shows small round cells.These cells are filled with which of the following: |
| A. | Glycogen |
| B. | Iron |
| C. | Fat |
| D. | Mucin |
| Answer» B. Iron | |
| 10. |
A highly ionized drug: |
| A. | Is well absorbed from the intestine |
| B. | Is highly protein bound |
| C. | Is excreted mainly by the kidneys |
| D. | Corsses the placental barrier easily |
| Answer» D. Corsses the placental barrier easily | |
| 11. |
A 40 year old hypertensive male was admitted to the hospital with sudden onset of headache and altered sensorium.On Examination his Blood Pressure was observed to be 220/110 mm Hg and the patient died four hours later.What is the likely pathological finding in his kidneys: |
| A. | Small kidney with peticheal haemorrhages |
| B. | Small kidney with granular surface |
| C. | Large kidney with granular surface |
| D. | Large kidney with waxy appearance |
| Answer» B. Small kidney with granular surface | |
| 12. |
Which of the following is a marker for Langerhans cell histiocytosis |
| A. | CD 30 |
| B. | CD 56 |
| C. | CD 1a |
| D. | CD 10 |
| Answer» D. CD 10 | |
| 13. |
Resolution of inflammation caused by ? |
| A. | TNF Alfa, IL-1 and CRP |
| B. | TNF Beta, IL-6 and CRP |
| C. | TNF Alfa, IL-10 and IL 1 receptor antagonist |
| D. | TNF gamma |
| Answer» D. TNF gamma | |
| 14. |
Most common cause of Abdominal aneurysm is |
| A. | Atherosclerosis |
| B. | Trauma |
| C. | Marfan's syndrome |
| D. | Congenital |
| Answer» B. Trauma | |
| 15. |
Bilateral hilar lymphadenopathy with non caseating granuloma is seen in - |
| A. | TB |
| B. | Lymphoma |
| C. | Sarcoidosis |
| D. | All of the above |
| Answer» D. All of the above | |
| 16. |
All the following malignancies are associated with HIV, except: |
| A. | Kaposi's Ca |
| B. | Non Hodgkin's lymphoma |
| C. | Astrocytoma |
| D. | Gastric adeno Ca |
| Answer» D. Gastric adeno Ca | |
| 17. |
Characteristic feature of still's disease - |
| A. | Prominent kidney involvement |
| B. | Rashes |
| C. | Positive Rheumatoid factor |
| D. | Neutropenia |
| Answer» C. Positive Rheumatoid factor | |
| 18. |
Which of the following is not true about enalapril |
| A. | It is a pro-drug |
| B. | It is a di-peptide |
| C. | It is more effective than captopril |
| D. | Has less adverse effects |
| Answer» C. It is more effective than captopril | |
| 19. |
All are predominant dilators, except - |
| A. | Diazoxide |
| B. | Minoxidil |
| C. | Hydralazine |
| D. | Na nitroprusside |
| Answer» E. | |
| 20. |
Bleomycin toxicity is characterized by Hyperplasia of |
| A. | Type I Pneumocytes |
| B. | Endothelial cells |
| C. | Alveolar macrophages |
| D. | Type II Pneumocytes |
| Answer» E. | |
| 21. |
Bevacizumab is ? |
| A. | Monoclonal antibody against VEGF |
| B. | Anti-IL-2 monoclonal antibody |
| C. | Monoclonal antibody against FGFR |
| D. | Monoclonal antibody against EGFR |
| Answer» B. Anti-IL-2 monoclonal antibody | |
| 22. |
Use of prostaglandin in pregnancy caused all except: |
| A. | Vomiting |
| B. | Bronchodilation |
| C. | Uterine rupture |
| D. | Fever |
| Answer» C. Uterine rupture | |
| 23. |
Regarding ACE inhibitor which of the following is true - |
| A. | T1/2 of enalapril is more than lisinopril |
| B. | Inhibits conversion of angiotensinogen to angiotensin 1. |
| C. | It is effective only with left ventricular systolic dysfunction |
| D. | Omission of prior diuretic dose decreases the risk of postural hypotension |
| Answer» E. | |
| 24. |
Which of the following is used to treat hormone-responsive breast cancer - |
| A. | Cytroterone acetate |
| B. | Clomiphene citrate |
| C. | Diethylstibestrol |
| D. | Tamoxifen |
| Answer» E. | |
| 25. |
Which of the following diuretics is contraindicated in the presence of cardiac failure ? |
| A. | Mannitol |
| B. | Spironolactone |
| C. | Furosemide |
| D. | Hydrochlorthiazide |
| Answer» B. Spironolactone | |
| 26. |
All are features of ethambutol toxicity, except - |
| A. | Retrobulbar neuritis |
| B. | Colour vision defects |
| C. | Hyperuricemia |
| D. | Hypercalcemia |
| Answer» E. | |
| 27. |
A child complains of nocturnal enuresis.The drug given to treat this is: |
| A. | Imipramine |
| B. | Clomipramine |
| C. | Fluoxetine |
| D. | Haloperidol |
| Answer» B. Clomipramine | |
| 28. |
Nicotine replacement therapy is available in all forms except - |
| A. | Chewing gum |
| B. | Lozenges |
| C. | Patch |
| D. | Tablets |
| Answer» E. | |
| 29. |
The common side effect with Fluoxetine therapy is: |
| A. | Hypotension |
| B. | Loose stools |
| C. | Seizure |
| D. | Anxiety |
| Answer» C. Seizure | |
| 30. |
Verapamil is contraindicated in all, except - |
| A. | PSVT with AV Block |
| B. | Variant angina |
| C. | Beta adrenergic toxicity |
| D. | Digitalis toxicity |
| Answer» C. Beta adrenergic toxicity | |
| 31. |
Carbamazepine has drug interaction with |
| A. | Erythromycin |
| B. | Phenytoin |
| C. | Doxycycline |
| D. | Barbiturates |
| Answer» B. Phenytoin | |
| 32. |
AFP is increased in- |
| A. | Endodermal sinus tumor |
| B. | Seminoma |
| C. | Dysgerminoma |
| D. | Choriocarcinoma |
| Answer» B. Seminoma | |
| 33. |
Thick mucous coat is : |
| A. | Easily destroyed by antacids |
| B. | Commonly associated with carcinomatous change |
| C. | Protective in ulcer patients |
| D. | Not protective in ulcer patients |
| Answer» D. Not protective in ulcer patients | |
| 34. |
Elevated levels of alkaline phosphatase are typical findings in each of the following conditions except - |
| A. | Cirrhosis |
| B. | Hepatitis |
| C. | Polycythemia vera |
| D. | Myocardial infarction |
| Answer» E. | |
| 35. |
A 7 year old boy presented with generalized edema.Urine examination revealed marked albuminuria.Serum biochemical examination showed hypoalbuminaemia with hyperlipidaemia.Kidney biopsy was undertaken.On light microscopic examination,the kidney appeared normal.Electron microscopic examination is most likely to reveal: |
| A. | Fusion of foot processes of the glomerular epithelial cells |
| B. | Rarefaction of glomerular basement membrane |
| C. | Deposition of electron dense material in the basement membrane |
| D. | Thin basement membrane |
| Answer» B. Rarefaction of glomerular basement membrane | |
| 36. |
True about gp. 120 is ? |
| A. | Virus attachment |
| B. | Virus penetration |
| C. | Virus detachment |
| D. | Virus dissemination |
| Answer» B. Virus penetration | |
| 37. |
Rosettes are characteristic in: |
| A. | Melanoma |
| B. | Dysgerminoma |
| C. | Retinoblastoma |
| D. | Lymphoma |
| Answer» D. Lymphoma | |
| 38. |
All of the following are Antigen Presenting Cells (APC) Except: |
| A. | Dendritic cells |
| B. | Langerhan's cell |
| C. | B-cells |
| D. | T-cells |
| Answer» E. | |
| 39. |
Treatment of choice for Paget's disease of the bone is |
| A. | Vitamin D |
| B. | Immobilization of the limb |
| C. | Surgical treatment |
| D. | Calcitonin |
| Answer» E. | |
| 40. |
Ortolani's test is used in - |
| A. | Congenital dislocation of knee |
| B. | Obstetric brachial plexus palsy |
| C. | Developmental dysplasia of hip |
| D. | Tom Smith's arthritis |
| Answer» D. Tom Smith's arthritis | |
| 41. |
A middle aged lady presents with complaints of lower back pain.On examination there is weakness of extension of right great toe with no sensory impairment.An MRI of the lumbosacral spine would be most probably reveal a prolapsed intervertebral disc at what level ? |
| A. | L3-L4 |
| B. | L4-L5 |
| C. | L5-S1 |
| D. | S1-S2 |
| Answer» C. L5-S1 | |
| 42. |
Which one of the following statements is true regarding drugs used in treatment of parkinsonism? |
| A. | amantidine causes ankle oedema |
| B. | levodopa is particularly effective in reducing tremors |
| C. | amantidine is more effective then levodopa |
| D. | antimuscarinics are effective in drug induced parkinsonism |
| Answer» B. levodopa is particularly effective in reducing tremors | |
| 43. |
Q angle is increased in ? |
| A. | Patellar subluxation |
| B. | Genu varum |
| C. | Femoral anteflexion |
| D. | Medial positioning tibial tuberosity |
| Answer» B. Genu varum | |
| 44. |
A patient presents with heterotopic ossification around the knee joint.The laboratory investigation of choice in him is: |
| A. | Serum calcium |
| B. | Serum Alkaline Phosphatase |
| C. | Serum phosphorus |
| D. | Serum Acid phosphatase |
| Answer» C. Serum phosphorus | |
| 45. |
Actions if atropine are all except |
| A. | Bronchoconstriction |
| B. | Tachycardia |
| C. | Mydriasis |
| D. | CNS stimulation |
| Answer» B. Tachycardia | |
| 46. |
Resistance to zidovudine develops due to - |
| A. | Mutations at reverse transcriptase |
| B. | Increased efflux of the drug from inside the cell |
| C. | Increased metabolism of the drug |
| D. | Decreased zidovudine 5 triphosphate formation |
| Answer» B. Increased efflux of the drug from inside the cell | |
| 47. |
Full vagolytic dose of atropine is________ micrograms/kg |
| A. | 10 |
| B. | 20 |
| C. | 30 |
| D. | 40 |
| Answer» E. | |
| 48. |
Which one of the following statements about biguanides is not true? |
| A. | Decrease hepatic glucose production |
| B. | Don't stimulate insulin Release |
| C. | Can be combined with sulfonylureas. |
| D. | Renal Dysfunction is not a contraindication for their use |
| Answer» E. | |
| 49. |
Red man syndrome occurs with - |
| A. | Clindamycin |
| B. | Teicoplanin |
| C. | Vancomycin |
| D. | Polymyxin |
| Answer» D. Polymyxin | |
| 50. |
Aspirin prolongs bleeding by inhibiting the synthesis of which of the following ? |
| A. | Adenosine receptors |
| B. | Cyclic AMP |
| C. | Prostacycline |
| D. | Thromboxane A2 |
| Answer» E. | |