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This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
All of the following drugs can precipitate Tacrolimus toxicity,Except: |
| A. | Vancomycin |
| B. | Rifampicin |
| C. | Gentamycin |
| D. | Cisplatin |
| Answer» C. Gentamycin | |
| 2. |
The following drug is not useful for MRSA - |
| A. | Cefaclor |
| B. | Cotrimoxazole |
| C. | Ciprofloxacin |
| D. | All of the above |
| Answer» B. Cotrimoxazole | |
| 3. |
Short elimination half-life (8-10 min) of esmolol (beta-1 adrenergic blocker) is due to - |
| A. | Rapid redistribution |
| B. | Rapid elimination by kidney |
| C. | Hydrolysis by blood esterases |
| D. | Rapid protein binding |
| Answer» D. Rapid protein binding | |
| 4. |
All are true regarding chloroquine,except: |
| A. | Acts only on exo erythrocytic cycle |
| B. | Acts on DNA and RNA of parasite |
| C. | Causes pigmentation of nail and mucosa |
| D. | Infected RBC has more drug |
| Answer» B. Acts on DNA and RNA of parasite | |
| 5. |
Heparin effect is increased by - |
| A. | Narcotic analgesics |
| B. | Non steroidal anti inflammatory drugs |
| C. | Oral contraceptives |
| D. | Inhalational agents |
| Answer» C. Oral contraceptives | |
| 6. |
Cause(s) of secondary brain injury is/are - |
| A. | Pyrexia and hypotension |
| B. | Seizures and metabolic disturbance |
| C. | Low cerebral perfusion pressure |
| D. | All of the above |
| Answer» E. | |
| 7. |
Coagulative necrosis may be seen in all of the following except: |
| A. | Tuberculosis |
| B. | Zenker's degeneration necrosis |
| C. | Myocardial infarction |
| D. | Thermal injury |
| Answer» C. Myocardial infarction | |
| 8. |
An elderly woman was admitted with a fracture of the neck of right femur which failed to unite.On examination an avascular necrosis of the head of femur was noted.The condition would have resulted most probably from the damage to: |
| A. | Superior gluteal artery |
| B. | Inferior gluteal artery |
| C. | Acetabular branch of obturator |
| D. | Retinacular branches of circumflex femoral arteries |
| Answer» E. | |
| 9. |
Most common charcot's joints involved in diabetes mellitus are those of: |
| A. | Knee |
| B. | Foot |
| C. | Shoulder |
| D. | Ankle |
| Answer» C. Shoulder | |
| 10. |
All of the following are characteristic of Turner syndrome except - |
| A. | Webbing of Neck |
| B. | Cubitus valgus |
| C. | Umbilical Hernia |
| D. | Coarctation of Aorta |
| Answer» D. Coarctation of Aorta | |
| 11. |
Deficiency of the 'intrinsic factor of Castle' causes |
| A. | Megaloblastic anemia |
| B. | Pernicious anemia |
| C. | Cooley's anemia |
| D. | Aplastic anemia |
| Answer» C. Cooley's anemia | |
| 12. |
Prolonged prothrombin time is seen in ? |
| A. | Haemophilia A |
| B. | Haemophilia B |
| C. | Thrombocytopenia |
| D. | Factor VII deficiency |
| Answer» E. | |
| 13. |
All are anxiolytic, except - |
| A. | Fluoxetine |
| B. | Buspirone |
| C. | Diazepam |
| D. | Nitrazepam |
| Answer» B. Buspirone | |
| 14. |
Which is not alkaloid ? |
| A. | Morphine |
| B. | Neostigmine |
| C. | Emetine |
| D. | Atropine |
| Answer» C. Emetine | |
| 15. |
The most potent and longest acting anesthetic agent is - |
| A. | Dibucaine |
| B. | Tetracaine |
| C. | Bupivacaine |
| D. | Lignocaine |
| Answer» B. Tetracaine | |
| 16. |
Sulphonamide injection causes decrease in folic acid by ? |
| A. | Competitive inhibition |
| B. | Non competitive inhibition |
| C. | Uncompetitive inhibition |
| D. | Allosteric inhibition |
| Answer» B. Non competitive inhibition | |
| 17. |
Which of the following statements about Graft Versus Host Disease (GVHD)is least correct: |
| A. | Occurs when donor cells are immunocompromised |
| B. | Occurs when host is immunocompromised |
| C. | A common cause is stem cell transplantation |
| D. | Is also called as Runt disease |
| Answer» B. Occurs when host is immunocompromised | |
| 18. |
A 35 yrs old patient has Ca lung,with a past history of lung disease.Which drug should not be given: |
| A. | Mithramycin |
| B. | Adriamycin |
| C. | Bleomycin |
| D. | Vinblastin |
| Answer» D. Vinblastin | |
| 19. |
Hypernatremia is caused by - |
| A. | Prednisolone |
| B. | Fludrocortisone |
| C. | Hydrocortisone |
| D. | Dexamethasone |
| Answer» C. Hydrocortisone | |
| 20. |
Which of the following does not worsen angina- |
| A. | Oxyfedrine |
| B. | Sumatriptan |
| C. | Thyroxime |
| D. | Dipyridamole |
| Answer» B. Sumatriptan | |
| 21. |
Which of the following about phenytoin is true - |
| A. | It is excreted unchanged in urine |
| B. | It is not teratogenic |
| C. | It follows zero order kinetics |
| D. | Not a hepatic enzyme inducer |
| Answer» D. Not a hepatic enzyme inducer | |
| 22. |
Procalcitonin is used as a marker for ? |
| A. | Sepsis |
| B. | Medullary carcinoma of thyroid |
| C. | Vitamin D resistant rickets |
| D. | Parathyroid adenoma |
| Answer» B. Medullary carcinoma of thyroid | |
| 23. |
Which among the following pairs of Oncogenes is activated by Translocation ? |
| A. | SIS and HST-1 |
| B. | HGF and L-MYC |
| C. | TGF alfa and CDK4 |
| D. | ABL and C-MYC |
| Answer» E. | |
| 24. |
Protein involved in intercellular connections is: |
| A. | Connexin |
| B. | Integrin |
| C. | Adhesin |
| D. | None of the above |
| Answer» B. Integrin | |
| 25. |
Russell bodies are |
| A. | Cytoplasmic inclusions seen in multiple myeloma |
| B. | Nuclear inclusions seen in multiple myeloma |
| C. | Both |
| D. | Nucleolar inclusions seen in multiple myeloma |
| Answer» B. Nuclear inclusions seen in multiple myeloma | |
| 26. |
Tetracycline inhibits protein synthesis by - |
| A. | Inhibiting initiation and causing misereading of mRNA |
| B. | Binding to 30 S subunit and inhibits binding of aminoacyl tRNA |
| C. | Inhibiting peptidyl transfearase activity |
| D. | Inhibiting translocation |
| Answer» C. Inhibiting peptidyl transfearase activity | |
| 27. |
Which of the following agents is recommended for treatment of Gastrointestinal Stromal Tumors(GIST) |
| A. | Imatinib |
| B. | Sorafenib |
| C. | Erlotinib |
| D. | Gefitinib |
| Answer» B. Sorafenib | |
| 28. |
All are false for ionized drugs except: |
| A. | Good oral absorption |
| B. | Mainly excreted by kidneys |
| C. | Accumulate in lipid bilayer |
| D. | Enters into the cell |
| Answer» C. Accumulate in lipid bilayer | |
| 29. |
Patients on amphotericin 'B' therapy may develop signs and symptoms of deficiency of one of the cations. This cation is - |
| A. | Sodium |
| B. | Potassium |
| C. | Magnesium |
| D. | Calcium |
| Answer» C. Magnesium | |
| 30. |
About follicular carcinoma of the thyroid gland - |
| A. | FNAC is diagnostic |
| B. | Lymph node metasteses are common |
| C. | Distant metastases are more common |
| D. | Local recurrence rates are low |
| Answer» D. Local recurrence rates are low | |
| 31. |
Best agent for premenstrual syndrome management? |
| A. | ANXIOLYTIC |
| B. | Progesterone |
| C. | vitamin E |
| D. | SSRI |
| Answer» E. | |
| 32. |
All of the following are drugs for ATT except: |
| A. | Cycloserine |
| B. | Kanamycin |
| C. | Ofloxacin |
| D. | 5-flucytosine |
| Answer» E. | |
| 33. |
Measurement of range of movement of joints: |
| A. | Goniometer |
| B. | Spondylometer |
| C. | Spriometer |
| D. | None |
| Answer» B. Spondylometer | |
| 34. |
Osteosarcoma arises from - |
| A. | Epiphysis |
| B. | Diaphysis |
| C. | Metaphysis |
| D. | Bone marrow |
| Answer» D. Bone marrow | |
| 35. |
After a brawl, a young male presented with inability to extend his distal interphalangeal joint. An X-ray was taken and was shown to be normal. What should be the next step in managing the patient? |
| A. | Wax bath |
| B. | Ignore |
| C. | Splint |
| D. | Surgery |
| Answer» D. Surgery | |
| 36. |
Clindamycin acts by inhibiting - |
| A. | Cell wall synthesis |
| B. | Protein synthesis |
| C. | Cell membrane synthesis |
| D. | Glucose utilization |
| Answer» C. Cell membrane synthesis | |
| 37. |
Lacunar cells are found in which of the following type of Hodgkin's lymphoma: |
| A. | Lymphocyte predominant |
| B. | Nodular sclerosis |
| C. | Lymphocyte depleted |
| D. | Mixed cellularity |
| Answer» C. Lymphocyte depleted | |
| 38. |
What is true about antinuclear antibody(ANA) - |
| A. | Anti-RNA antibody is specific for SLE |
| B. | Double stranded Anti-DNA is specific for SLE |
| C. | ANA normally present in 80% |
| D. | None of the above |
| Answer» C. ANA normally present in 80% | |
| 39. |
All the following statements regarding interactions of levodopa are correct except: |
| A. | Pyridoxine reduces effect of revodopa in Parkinsomism |
| B. | Domperidone blocks levodopa induced emesis and its therapeutic potential |
| C. | In Parkinsonism,phenothiazines reduce its efficacy |
| D. | It is a prodrug |
| Answer» C. In Parkinsonism,phenothiazines reduce its efficacy | |
| 40. |
Epsilon aminocaproic acid is used to reduce bleeding due to |
| A. | Heparin |
| B. | Warfarin |
| C. | Thrombocytopenia |
| D. | Hyperplasminaemia |
| Answer» E. | |
| 41. |
All of the following statements are true about nitrates except: |
| A. | It causes vasodilatation |
| B. | It releases NO |
| C. | It has high first pass metabolism |
| D. | It decreases A.V. conduction |
| Answer» E. | |
| 42. |
Which drug has the least anti-cholinergic side effects |
| A. | Imipramine |
| B. | Doxepin |
| C. | Fluoxetine |
| D. | Chlomipramine |
| Answer» D. Chlomipramine | |
| 43. |
LE cell phenomenon is seen in - |
| A. | Lymphocyte |
| B. | Neutrophil |
| C. | Monocyte |
| D. | Eosinophil |
| Answer» C. Monocyte | |
| 44. |
Major mineral of the bone is - |
| A. | Hydroxyapatite |
| B. | Calcite |
| C. | Calcium carbonate |
| D. | Calcium oxide |
| Answer» B. Calcite | |
| 45. |
The chemotherapeutic agent, most commonly administered by continuous infusion is - |
| A. | Ara - C |
| B. | F - FU |
| C. | Cisplatin |
| D. | Etoposide |
| Answer» B. F - FU | |
| 46. |
Ondansetron is a potent |
| A. | Antiemetic |
| B. | Anxiolytic |
| C. | Analgesic |
| D. | Antidepressant |
| Answer» B. Anxiolytic | |
| 47. |
Cyclosporine is active against - |
| A. | CD4 and lymphocytes |
| B. | CD8 and lymphocytes |
| C. | CD14 and lymphocytes |
| D. | B lymphocytes |
| Answer» B. CD8 and lymphocytes | |
| 48. |
Thiazide diuretic used when GFR |
| A. | Metolazone |
| B. | Benzthiazide |
| C. | Chrorthiazide |
| D. | Hydrofulthiazide |
| Answer» B. Benzthiazide | |
| 49. |
All the drugs used in chronic pain syndrome except: |
| A. | Phenytoin |
| B. | Carbamazepine |
| C. | Valproate |
| D. | Clonazepam |
| Answer» D. Clonazepam | |
| 50. |
Rifampicin acts by ? |
| A. | DNA dependent RNA polymerase |
| B. | RNA dependent DNA polymerase |
| C. | Mycolic acid inhibition |
| D. | Mycolic acid incorporation defects |
| Answer» B. RNA dependent DNA polymerase | |