MCQOPTIONS
Saved Bookmarks
MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following is not a disaccharide: |
| A. | Sucrose |
| B. | Fructose |
| C. | Maltose |
| D. | Lactose |
| Answer» C. Maltose | |
| 2. |
Which of the following is correct in regards off function of phospholipid - |
| A. | Cell-cell interaction |
| B. | Signal transduction |
| C. | Surfactant |
| D. | All of the above |
| Answer» E. | |
| 3. |
To synthesis insulin on a large scale basis, the most suitable starting material obtainedd from the beta cells of the pancreas is - |
| A. | Genomic DNA |
| B. | Total cellular RNA |
| C. | cDNA of insulin |
| D. | mRNA of insulin |
| Answer» E. | |
| 4. |
The conversion of an optically pure isomer (enantiomer) into a mixture of equal amounts of both dextro and levo forms is called as: |
| A. | Stereoisomerization |
| B. | Polymerization |
| C. | Fractionation |
| D. | Racemization |
| Answer» E. | |
| 5. |
The transmembrane region of protein is likely to have: |
| A. | A stretch of hydrophobic amino acids |
| B. | A stretch of hydrophilic amino acids |
| C. | Alternating hydrophilic and hydrophobic amino acids |
| D. | A disulphide loop |
| Answer» B. A stretch of hydrophilic amino acids | |
| 6. |
Atherosclerosis is more related to decreased level of: |
| A. | HDL-1 |
| B. | HDL-2 |
| C. | HDL-3 |
| D. | Pre Beta HDL |
| Answer» C. HDL-3 | |
| 7. |
After digestion by restriction endonucleases DNA strands can be joined again by |
| A. | DNA ligase |
| B. | DNA polymerase |
| C. | DNA gyrase |
| D. | DNA topoisomerase |
| Answer» B. DNA polymerase | |
| 8. |
Taurine is formed by the amino acid |
| A. | Tyrosine |
| B. | Cysteine |
| C. | Tryptophan |
| D. | Histidine |
| Answer» C. Tryptophan | |
| 9. |
Iron absorption is facilitated by all the following EXCEPT |
| A. | Idiopathic hemochromatosis |
| B. | Celiac sprue |
| C. | Portocaval shunt |
| D. | Organic form of iron in diet |
| Answer» C. Portocaval shunt | |
| 10. |
The property of proteins to absorb ultraviolet rays of light is due to - |
| A. | Di Sulphide bond |
| B. | Aromatic amino bond |
| C. | Peptide bond |
| D. | Imino group |
| Answer» C. Peptide bond | |
| 11. |
At isoelectric pH protein - |
| A. | Are negatively charged |
| B. | Don't migrate |
| C. | Have Net charge 'O' |
| D. | Are positively charged |
| Answer» D. Are positively charged | |
| 12. |
The enzyme deficient in erythropoietic porphyria is - |
| A. | Coprophyrin |
| B. | Ferrochelatase |
| C. | PBG deaminase |
| D. | Uroporphyrin II cosynthetase |
| Answer» C. PBG deaminase | |
| 13. |
Which of the following metabolic events will not occur following 12-24 hour fasting: |
| A. | Decrease in Glycogen |
| B. | Decrease in Serum Protiens |
| C. | Increase in Free Fatty Acids |
| D. | Increase in Ketone bodies |
| Answer» C. Increase in Free Fatty Acids | |
| 14. |
Substrate level phosphorylation is caused by - |
| A. | Thiokinase |
| B. | Succinate dehydrogenase |
| C. | Hexokinase |
| D. | Malate dehydrogenase |
| Answer» B. Succinate dehydrogenase | |
| 15. |
Strongest bond out of the following is: |
| A. | Hydrophobic |
| B. | Vanderwall's |
| C. | Electrostatic |
| D. | Hydrogen |
| Answer» D. Hydrogen | |
| 16. |
G6 phosphate deficiency seen in - |
| A. | Taysach's disease |
| B. | Anderson's disease |
| C. | Von Gierke's disease |
| D. | Pompe's disease |
| Answer» D. Pompe's disease | |
| 17. |
The primary defect in Xeroderma pigmentosa is: |
| A. | Exonuclease is defective |
| B. | Formation of adenine dimers |
| C. | Formation of thymidine dimers |
| D. | Poly ADP ribose polymerase is defective |
| Answer» D. Poly ADP ribose polymerase is defective | |
| 18. |
DNA synthesis occurs in the stage of: |
| A. | S |
| B. | G1 |
| C. | M |
| D. | G2 |
| Answer» B. G1 | |
| 19. |
The following separation technique depends on the molecular size of the protein: |
| A. | Iso-electric focussing |
| B. | Chromatography on a carboxymethyl(CM) cellulose column |
| C. | Chromatography on a diethylaminoethyl (DEAE) cellulose column |
| D. | Gel filtration chromatography |
| Answer» E. | |
| 20. |
Null mutation is: |
| A. | Mutation that codes for a change in progeny without any chromosomal change |
| B. | Mutation that leads to no functional gene product |
| C. | Mutation occuring in Non Coding region |
| D. | Mutation that does not change the amino acid or end product |
| Answer» C. Mutation occuring in Non Coding region | |
| 21. |
Guanido acitic acid formed in... from - |
| A. | Liver; Cysteine + Arginine |
| B. | Muscle; Citrulline + Aspartate |
| C. | Kidney; Arginine + Glycine |
| D. | Liver; Methionine + Glycine |
| Answer» D. Liver; Methionine + Glycine | |
| 22. |
True about restriction enzymes - |
| A. | Palindromic |
| B. | Produce DNA sticky end |
| C. | Restrict replication of DNA |
| D. | All of the above |
| Answer» E. | |
| 23. |
Ideal total cholesterol to HDL cholesterol ratio is ? |
| A. | 1.5 |
| B. | 2.5 |
| C. | 3.5 |
| D. | 4.5 |
| Answer» D. 4.5 | |
| 24. |
A four-year-old child is diagnosed with Duchenne muscular dystrophy, an X-linked recessive disorder. Genetic analysis shows that the patient's gene for the muscle protein dystrophin contains a mutation in its promoter region. What would be the most likely effect of this mutation ? |
| A. | Termination of dystrophin transcription will be deficient |
| B. | Initiation of dystrophin transcription will be deficient |
| C. | Tailing of dystrophin mRNA will be defective. |
| D. | Capping of dystrophin mRNA will be defective |
| Answer» C. Tailing of dystrophin mRNA will be defective. | |
| 25. |
Dietary triglycerides are transported by |
| A. | Chylomicrons |
| B. | VLDL |
| C. | LDL |
| D. | HDL |
| Answer» B. VLDL | |
| 26. |
Mitochondria is involved in all of the following, except - |
| A. | Tricarboxylic acid cycle |
| B. | Fatty acid biosynthesis |
| C. | ATP production |
| D. | Apoptosis |
| Answer» C. ATP production | |
| 27. |
R-RNA is mainly produced in - |
| A. | Nucleolus |
| B. | Nucleus |
| C. | Endoplasmic reticulm |
| D. | Ribosome |
| Answer» B. Nucleus | |
| 28. |
Correct statement regarding restriction endonuclease is - |
| A. | Restriction endouclease recognizes specific sites of DNA sequence |
| B. | Itacts at 5' - 3' direction |
| C. | Itacts at 3' - 5' direction |
| D. | All of the above |
| Answer» B. Itacts at 5' - 3' direction | |
| 29. |
Amino acid which lacks chirality is: |
| A. | Lysine |
| B. | Leucine |
| C. | Histidine |
| D. | Glycine |
| Answer» E. | |
| 30. |
Replication and transcription are similar process in mechanistic terms because both - |
| A. | Are semi conserved events |
| B. | Involve phosphodiester bond formation with elongation occurring in the 5' - 3' direction |
| C. | Use RNA primers for inintiation . |
| D. | Use dioxyribonucleotides as precursors |
| Answer» C. Use RNA primers for inintiation . | |
| 31. |
Viscosity of synovial fluid depends upon: |
| A. | N-acetyl galactosamine |
| B. | N-acetyl glucosamine |
| C. | Glucuronic acid |
| D. | Hyaluronic acid |
| Answer» E. | |
| 32. |
Not true among the following is - |
| A. | SRP blocks elongation |
| B. | SRP-R is ATP bond |
| C. | Sec 61 translocon complex form passage way |
| D. | SRP-R docking protein |
| Answer» C. Sec 61 translocon complex form passage way | |
| 33. |
True about DNA structure - |
| A. | Watson and Crick discorvered structure in 1973 |
| B. | Purines are adenne and guanine and pyrimidines are uracil and cytosine |
| C. | Mainly consists of left handed helix |
| D. | Deoxyribose-phosphate backbone with bases stacked inside |
| Answer» E. | |
| 34. |
In cholesterol synthesis, which rate limiting amino acid - |
| A. | HMG CoA Reductase |
| B. | HMG CoA synthetase |
| C. | 7 alpha hydroxylase |
| D. | Phosphofructokinase |
| Answer» B. HMG CoA synthetase | |
| 35. |
All of the following metabolic changes occur during prolonged fasting when compared with fasting for 12-24 hours,except: |
| A. | Liver gluconeogenesis increases |
| B. | Brain use of ketone bodies increases |
| C. | Brain use of glucose decreases |
| D. | Muscle protein degradation decreases |
| Answer» B. Brain use of ketone bodies increases | |
| 36. |
Prophobilinogen in urine produces pink colour with: |
| A. | Sodium nitropruside |
| B. | Ehrlich's aldehyde reagent |
| C. | Fouchet's reagent |
| D. | Benedict's reagent |
| Answer» C. Fouchet's reagent | |
| 37. |
Which of the following enzyme does NOT take part in the conversion of lactate to phosphoenolpyruvate ? |
| A. | Lactate dehydrogenase |
| B. | Pyruvate kinase |
| C. | Pyruvate carboxylase |
| D. | Phosphoenolpyruvate carboxylase |
| Answer» C. Pyruvate carboxylase | |
| 38. |
False statement about hemoglobin structure ? |
| A. | Hb structurally similar to myoglobin |
| B. | Ferrous ions are in porphyrin rings |
| C. | Hb has 2 polypeptide |
| D. | Iron is present in ferrous atate |
| Answer» D. Iron is present in ferrous atate | |
| 39. |
Bita oxidation is peroxisome is differentiated from that occurring in mitochondria by - |
| A. | H2O2 formed |
| B. | Acetyl CoA |
| C. | NADH is required |
| D. | Differene enzymes are found in different sites |
| Answer» B. Acetyl CoA | |
| 40. |
Inositic acid is biological precursor of - |
| A. | Purines and thymine |
| B. | Uracil and thymine |
| C. | Orotic acid and uridylic acid |
| D. | Adeylic and guanylic acid |
| Answer» E. | |
| 41. |
The predominant isozyme of LDH in cardiac muscle is: |
| A. | LD-3. |
| B. | LD-5 |
| C. | LD-1. |
| D. | LD-2 |
| Answer» D. LD-2 | |
| 42. |
Fluroacetate inhibits - |
| A. | Aconitase |
| B. | Citrate synthetase |
| C. | Alphaketoglutarate dehydrogenase |
| D. | Succinate dehydrogenase |
| Answer» B. Citrate synthetase | |
| 43. |
False about neoglucogenesis is: |
| A. | Occurs in normal persons with overnight fasting |
| B. | All steps of glycolysis is reversed |
| C. | 1,6 Fructose bisphosphatase is an importanrt regulatory enzyme of neoglucogenesis |
| D. | The major substrates are the glucogenic amino acids,and lactate,glycerol and propionate |
| Answer» C. 1,6 Fructose bisphosphatase is an importanrt regulatory enzyme of neoglucogenesis | |
| 44. |
All of the following are arachidonic acid metabolism except- |
| A. | Lipoxins |
| B. | Leukotrienes |
| C. | Serotonin |
| D. | Prostaglandins |
| Answer» D. Prostaglandins | |
| 45. |
Essential fructosuria is due to deficiency of |
| A. | Aldolase B |
| B. | Fructokinase |
| C. | G-6 phosphatase deficiency |
| D. | Alpha -Galactosidase deficiency |
| Answer» C. G-6 phosphatase deficiency | |
| 46. |
Essential amino acids include all except - |
| A. | Methionine |
| B. | Tryptophan |
| C. | Leucine |
| D. | Alanine |
| Answer» E. | |
| 47. |
The vitamin used for transmination is - |
| A. | Pyridoxal phosphate |
| B. | Riboflavin |
| C. | Thiamine |
| D. | Cyanocobalamine |
| Answer» B. Riboflavin | |
| 48. |
Gluconeogenesis affects A/E: |
| A. | Alanine |
| B. | Growth hormone |
| C. | Lactate |
| D. | Glycerol |
| Answer» C. Lactate | |
| 49. |
NADPH is required for |
| A. | Glycolysis |
| B. | Gluconeogenesis |
| C. | Glycogenolysis |
| D. | Fatty acids synthesis |
| Answer» E. | |
| 50. |
Two transgenic plants were genetically engineered using Recombinant DNA technology.One plant was transformed using a plasmid vector with GFP(Green Fluorescent Protein) gene and another plant was transformed with Luciferase gene.Which of these two plants will glow spontaneously in the dark: |
| A. | Plant with GFP Gene |
| B. | Plant with Luciferase Gene |
| C. | Both plants |
| D. | None of the above |
| Answer» E. | |