MCQOPTIONS
Saved Bookmarks
MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The end produced of one stage fermentation is - |
| A. | Lactate |
| B. | Ethanol |
| C. | Formic acid |
| D. | Pyruvate |
| Answer» C. Formic acid | |
| 2. |
Regarding synthesis of triacyl glycerol in adipose tissue,all of the following are true except: |
| A. | Synthesis from Dihydroxyacetone phosphate |
| B. | Enzyme Glycerol Kinase plays an important role |
| C. | Enzyme Glucerol 3 phosphate dehydrogenase plays an important role |
| D. | Phosphatidate is hydrolyzed |
| Answer» C. Enzyme Glucerol 3 phosphate dehydrogenase plays an important role | |
| 3. |
Formation of glucose from alanine is termed as - |
| A. | Glycolysis |
| B. | Oxidative decarboxylation |
| C. | Gluconeogenesis |
| D. | Transamination |
| Answer» D. Transamination | |
| 4. |
An amino acid which does not participate by alpha helix formation is |
| A. | Leucine |
| B. | Glycine |
| C. | Proline |
| D. | Lysine |
| Answer» D. Lysine | |
| 5. |
In oxidative phosphorylation,the ATP production and respiratory chain are linked by: |
| A. | Physical methods |
| B. | Chemical methods |
| C. | Conformational changes |
| D. | Chemiosmotic methods |
| Answer» E. | |
| 6. |
Carboxylation of clotting factors by vitamin K is required to be biologically active. Which of the following amino acid is carboxylated? |
| A. | Histamine |
| B. | Histidine |
| C. | Aspartate |
| D. | Glutamate |
| Answer» E. | |
| 7. |
Cancer cells derived nutrition from - |
| A. | Increase in mitochondria |
| B. | From a fast food joint |
| C. | Glycolysis |
| D. | Oxidative phosphorylation |
| Answer» D. Oxidative phosphorylation | |
| 8. |
Insulin acts on which enzyme in glycoysis - |
| A. | Glucose 6-phosphate |
| B. | Andeylate kinase |
| C. | Glucokinase |
| D. | Hexokinase |
| Answer» D. Hexokinase | |
| 9. |
Primary disturbance in metabolic alkalosis is characterized by one of the following - |
| A. | Increased pCO2 |
| B. | Increased HCO3 |
| C. | Decreased pO2 |
| D. | Decreased pH |
| Answer» C. Decreased pO2 | |
| 10. |
Enzyme to both common in gluconegenesis and glycolysis pathway is: |
| A. | Hexokinase |
| B. | Glucose 6 phosphatase |
| C. | Phosphofructokinase |
| D. | Fructose 2,6-biphosphatase |
| Answer» D. Fructose 2,6-biphosphatase | |
| 11. |
The rate-limiting enzyme in Glycolysis is: |
| A. | Glucokinase |
| B. | Pyruvate kinase |
| C. | Phosphofructokinase |
| D. | Glucose-6-dehydrogenase |
| Answer» D. Glucose-6-dehydrogenase | |
| 12. |
NAD acts as a cofactor for |
| A. | Isocitrate dehydrogenase |
| B. | Alpha-ketoglutrate dehydrogenase |
| C. | Malate dehydrogenase |
| D. | All of the above |
| Answer» E. | |
| 13. |
De-branching enzyme in glycogenolysis hydrolyses which one of the following bonds to release free glucose ? |
| A. | a (1-4) |
| B. | a (1-6) |
| C. | p (1-4) |
| D. | 3 (1-6) |
| Answer» C. p (1-4) | |
| 14. |
In DNA transfer the vectors used from smallest to largest is: |
| A. | Bacteriophage,Cosmides,Plasmids |
| B. | Plasmids,Bacteriophage,Cosmids |
| C. | Cosmids,Bacteriophage,Plasmids |
| D. | Cosmids,Plasmids,Bacteriophage |
| Answer» C. Cosmids,Bacteriophage,Plasmids | |
| 15. |
Substrate-level phosphorylation seen in reaction catalysed in- |
| A. | Alfa-ketoglutrate dehydrogenase |
| B. | Succinate dehydrogenase |
| C. | Malate dehydrogenase |
| D. | Succinyl CoA thiokinase |
| Answer» E. | |
| 16. |
Which of the following process in a vector is used to increase the yield of protein produced in recombinant protein synthesis: |
| A. | Translation of Initiation |
| B. | Translation and Transcription inhibition |
| C. | Promoter induction |
| D. | Origin of Replication |
| Answer» D. Origin of Replication | |
| 17. |
The inhibitor of complex IV of electron transport chain is - |
| A. | Barbiturates |
| B. | Antimycin A |
| C. | Hydrogen sulfide |
| D. | Dimercaprol |
| Answer» D. Dimercaprol | |
| 18. |
True a bout coding strand of DNA - |
| A. | Plus strand |
| B. | Matches with RNA transcript hat encodes protein |
| C. | DNA acts as template for mRNA |
| D. | Minus strand |
| Answer» C. DNA acts as template for mRNA | |
| 19. |
Which of the following are situated away from the coding region - |
| A. | Promoter |
| B. | Enhancer |
| C. | Operator |
| D. | All of the above |
| Answer» E. | |
| 20. |
Which amino acid is required in pyrimidine biosynthesis: |
| A. | Glycine |
| B. | Valine |
| C. | Glutamate |
| D. | Aspartate |
| Answer» E. | |
| 21. |
Which of the following increases the activity of lipoprotein lipase: |
| A. | Glucagon |
| B. | Insulin |
| C. | Thyroxine |
| D. | Epinephrine |
| Answer» C. Thyroxine | |
| 22. |
Separation of molecules based on molecular size: |
| A. | Ion exchange chromatography |
| B. | PAGE |
| C. | Isoelectric focusing |
| D. | Molecular exclusion chromatography |
| Answer» C. Isoelectric focusing | |
| 23. |
True about glutamate dehydrogenase is A/E - |
| A. | Use both NAD+or NADP + coenzyme |
| B. | Liver mitochondria enzyme |
| C. | Reversible oxidative deamination |
| D. | Inhibited by ADP and activated by GTP |
| Answer» E. | |
| 24. |
Frame shift mutation does not occur in multiples of ? |
| A. | 2 |
| B. | 3 |
| C. | 4 |
| D. | 5 |
| Answer» C. 4 | |
| 25. |
True about DNA supercoiling is all except - |
| A. | Superhelical density depends on length of DNA |
| B. | Underwinding results in negative superhelical density and supercoiling |
| C. | Most cellular DNA is underwound |
| D. | Topoisomerase II change linking number in increments of 2 |
| Answer» B. Underwinding results in negative superhelical density and supercoiling | |
| 26. |
High energy phosphate compounds are - |
| A. | ATP |
| B. | Acetyl CoA |
| C. | Creatinine phosphate |
| D. | All of the above |
| Answer» E. | |
| 27. |
Pyruvate dehydrogenase enzyme complex contains the following co-factor except - |
| A. | Thiamine pyrophosphate |
| B. | Co-enzyme A |
| C. | Flavin Adenine Dinucleotide (FAD) |
| D. | Nicotinamide Adenine Dinucleotide Phosphate (NADP) |
| Answer» E. | |
| 28. |
Alpha helix and Beta pleated sheet are examples of: |
| A. | Secondary structure |
| B. | Primary structure |
| C. | Quaternary structure |
| D. | Tertiary structure |
| Answer» B. Primary structure | |
| 29. |
Which type of RNA has the highest percentage of modified base? |
| A. | tRNA |
| B. | mRNA |
| C. | snRNA |
| D. | rRNA |
| Answer» B. mRNA | |
| 30. |
Stop codon - |
| A. | UAC |
| B. | AUG |
| C. | UAG |
| D. | UCA |
| Answer» D. UCA | |
| 31. |
Which of the following methods is most suited to assess function of a gene: |
| A. | Gene knockout animals |
| B. | Transgenic animals |
| C. | Southern blot |
| D. | Northern blot |
| Answer» C. Southern blot | |
| 32. |
Regarding ribosome all is true except - |
| A. | Large subunit catalyzes peptide bond formation |
| B. | Binding of aminoacyl tRNA uses 2ATP |
| C. | 16 ribosome identifies shine - dalgarno sequence |
| D. | Cytolosic ribosomes synthesixed of peroxisome |
| Answer» C. 16 ribosome identifies shine - dalgarno sequence | |
| 33. |
ATP's are formed in the following steps of Kreb's cycle - |
| A. | Isocitrate dehydrogenase |
| B. | Succinate dehydrogenase |
| C. | Succinate thiokinase |
| D. | All of the above |
| Answer» E. | |
| 34. |
All the following can be used to detect mutation,except: |
| A. | Ligase chain reaction |
| B. | Single strand conformational polymorphism |
| C. | DNA Sequencing |
| D. | Polymerase chain reaction |
| Answer» B. Single strand conformational polymorphism | |
| 35. |
Colonic bacteria,on digestion of dietary fibres would give- |
| A. | Free radicals |
| B. | Glycerol |
| C. | Butyrate |
| D. | Sucrose |
| Answer» D. Sucrose | |
| 36. |
Which of the following molecular phenomenon in Ig genes is responsible for affinity maturation of antibody response |
| A. | Junctional diverity |
| B. | Chain shuffling |
| C. | Altered RAA splicing |
| D. | Somatic hypermutation |
| Answer» E. | |
| 37. |
All of the following cell types contain the enzyme telemerase which protects the length of telomeres at the end of chromosomes,except: |
| A. | Somatic |
| B. | Germinal |
| C. | Tumor |
| D. | Hemopoietic |
| Answer» B. Germinal | |
| 38. |
In a well fed state,acetyl CoA obtained from diet is least used in the synthesis of: |
| A. | Citrate |
| B. | Palmity CoA |
| C. | Oxalosuccinate |
| D. | Acetoacetate |
| Answer» E. | |
| 39. |
Which of following group of proteins assist in the 'folding' of other proteins? |
| A. | Templates |
| B. | Chaperones |
| C. | Proteases |
| D. | Proteosomes |
| Answer» C. Proteases | |
| 40. |
Amino acid with dissociation constant closest to physiological pH is: |
| A. | Histidine |
| B. | Serine |
| C. | Proline |
| D. | Threonine |
| Answer» B. Serine | |
| 41. |
Mitochondrial membrane protein contain transport of - |
| A. | NADH |
| B. | NADPH |
| C. | ATP |
| D. | All of the above |
| Answer» E. | |
| 42. |
DNA Amplification is done in - |
| A. | PCR |
| B. | NASBA(Nuclei acid sequential based amplification) |
| C. | Liase chain reaction |
| D. | All of the above |
| Answer» E. | |
| 43. |
Light microscope resolution to visualise chromosomes - |
| A. | 500 kb |
| B. | 5 mb |
| C. | 50 mb |
| D. | 5 kb |
| Answer» E. | |
| 44. |
Coenzymes for pyruvate dehydrogenase are A/E - |
| A. | FAD |
| B. | NADPH |
| C. | TPP |
| D. | CoA |
| Answer» C. TPP | |
| 45. |
Phenylalanine is the precursor of all the following,EXCEPT: |
| A. | Thyroxine |
| B. | Melatonin |
| C. | Tyrosine |
| D. | Epinephrine |
| Answer» C. Tyrosine | |
| 46. |
Micro to RNA transcribed by - |
| A. | RNA polymerase II |
| B. | RNA polymerase I |
| C. | DNA polymerase |
| D. | RNA polymerase III |
| Answer» B. RNA polymerase I | |
| 47. |
Which of the following membrane has the highest protein content per gram tissue: |
| A. | Inner mitochondrial membrane |
| B. | Outer mitochondrial membrane |
| C. | Plasma membrane |
| D. | Myelin sheath |
| Answer» B. Outer mitochondrial membrane | |
| 48. |
The type of enzyme inhibition -in which succinate dehydrogenase reaction is inhibited by malonate is an example of - |
| A. | Uncompetitive |
| B. | Noncompetitive |
| C. | Allosteric |
| D. | Competitive |
| Answer» E. | |
| 49. |
Which is not found in DNA |
| A. | Adenine |
| B. | Thymine |
| C. | Guanine |
| D. | Uracil |
| Answer» E. | |
| 50. |
Not a fatty acid synthase component - |
| A. | Acetyl coa carboxylase |
| B. | Enoyl reductase |
| C. | Acyl coa |
| D. | Keto acyl synthase |
| Answer» B. Enoyl reductase | |