MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In competitive inhibition - |
| A. | Appraent km decreased |
| B. | Vmax decreased |
| C. | Vmax unchanged |
| D. | Appraent km unchanged |
| Answer» D. Appraent km unchanged | |
| 2. |
All of the following statements about Lipoprotein Lipase are true,Except |
| A. | Deficiency leads to hypertriacylglycerolemia |
| B. | Does not require CII as cofactor |
| C. | Found in adipose tissue |
| D. | Found in myocytes |
| Answer» C. Found in adipose tissue | |
| 3. |
Which of the following is not true for an Alpha-helix - |
| A. | All hydrgen bonds are aligned in the same direction |
| B. | Long stretches of the left handed Alpha-helix occur in proteins |
| C. | It is one of the most important secondary structure |
| D. | It has a net dipole moment |
| Answer» C. It is one of the most important secondary structure | |
| 4. |
Reducing sugar in urine is seen in - |
| A. | Lactose intolerance |
| B. | Fanconi anemia |
| C. | Salicylate poisoning |
| D. | Galactosemia |
| Answer» E. | |
| 5. |
Leucine-Zipper complex is - |
| A. | B cell epitomes |
| B. | Receptor ligand protein |
| C. | DNA binding protein |
| D. | Membrane attack complex |
| Answer» D. Membrane attack complex | |
| 6. |
Biotins act on: |
| A. | Carboxylation |
| B. | Oxydative phosphorylation |
| C. | Oxydative deamination |
| D. | Transmethylation |
| Answer» B. Oxydative phosphorylation | |
| 7. |
The marker enzyme of peroxisome is: |
| A. | LDH |
| B. | Glutamate dehydrogenase |
| C. | 5-Nucleotidase |
| D. | Catalase |
| Answer» E. | |
| 8. |
Which of the following is a component of polysaccharide - |
| A. | Glucosamine |
| B. | Synovium |
| C. | Ascorbic acid |
| D. | Glucoronic acid |
| Answer» B. Synovium | |
| 9. |
Which one of the following statements about the urea cycle is correct - |
| A. | The pathway occurs exclusively in mitochondrial matrix of liver |
| B. | ATP required for the reaction in which citrulline is formed |
| C. | Two nitrogen atoms that are incorporated into urea enter the cycle as ammonia and aspartate |
| D. | Urea is produced directly by the hydrolysis of omithine |
| Answer» D. Urea is produced directly by the hydrolysis of omithine | |
| 10. |
Enzyme replacement is done for ? |
| A. | Niemann pick's |
| B. | Gangliosidose |
| C. | Gaucher's disease |
| D. | Phenylketonuria |
| Answer» D. Phenylketonuria | |
| 11. |
tRNA met would recognize - |
| A. | GUC |
| B. | GCU |
| C. | AUG |
| D. | UGC |
| Answer» D. UGC | |
| 12. |
Which of the following types of hypertriglyceridemia is associated with an increase in chylomicron and VLDL remnants? |
| A. | Type IIa |
| B. | Type I |
| C. | Type IV |
| D. | Type III |
| Answer» E. | |
| 13. |
Insulin stimulated glucose uptake is by ? |
| A. | SGLT-1 |
| B. | GLUT-1 |
| C. | GLUT-2 |
| D. | GLUT-4 |
| Answer» E. | |
| 14. |
By which of the following anticoagulants used in estimating blood glucose, glycolysis is prevented - |
| A. | EDTA |
| B. | Heparin |
| C. | Sodium fluoride |
| D. | Sodium citrate |
| Answer» D. Sodium citrate | |
| 15. |
Substitution of which one of the following amino acids in place of alanine would increase the absorbance of protein at 20 nm - |
| A. | Leucine |
| B. | Arginine |
| C. | Tryptophan |
| D. | Prolein |
| Answer» D. Prolein | |
| 16. |
Restriction Endonuncleas function - true about - |
| A. | Cut both the strands of ds DNA |
| B. | The cut ends produced are sticky |
| C. | The cut ends produced are blunt |
| D. | All of the above |
| Answer» E. | |
| 17. |
Ends chromosomes replicated by - |
| A. | Restriction endounclease |
| B. | Exonuclease |
| C. | Telomerase |
| D. | Centromere |
| Answer» D. Centromere | |
| 18. |
The protein rich in basic amino acids,which functions in the packaging of DNA in chromosomes is: |
| A. | Hyaluronic acid binding protein |
| B. | Fibrinogen |
| C. | Histone |
| D. | Collagen |
| Answer» D. Collagen | |
| 19. |
Glucose can be synthesised from all of the following except: |
| A. | Glycerol |
| B. | Amino Acid |
| C. | Acetoacetate |
| D. | Lactic Acid |
| Answer» D. Lactic Acid | |
| 20. |
Insulin causes lipogenesis by all except - |
| A. | Increases the transport of glucose into the cells |
| B. | Increasing acetyl-CoA carboxylase activity |
| C. | Decreased intracellular cAMP level |
| D. | Inhibits pyruvate dehydrogenase |
| Answer» E. | |
| 21. |
The cellular component for protein synthesis is: |
| A. | Rough endoplasmic reticulum |
| B. | Smooth endoplasmic reticulum |
| C. | Mitochondria |
| D. | Ribosomes |
| Answer» E. | |
| 22. |
Incorrect statement are - |
| A. | Restriction endonuclease cut DNA chains at specific location |
| B. | Klenow fragment of DNA polymerase I function is almost similar to T4 DNA polymerase |
| C. | Right handed helix of DNA is more common |
| D. | Endonuclease cut DNA at 5' terminus |
| Answer» E. | |
| 23. |
Branched chin ketoacid decarboxylation is defective in |
| A. | Alkaptonuria |
| B. | GM1 Gangliosidosis |
| C. | Maple Syrup urine disease |
| D. | Hartnup disease |
| Answer» D. Hartnup disease | |
| 24. |
A common feature of all serine proteases is: |
| A. | Cleavage of protein on the carboxyl site of serine residues |
| B. | Presence of Ser-His-Asp catalytic triad at the active site |
| C. | Autocatalytic activation of zymogen precursor |
| D. | Tight binding of pancreatic trypsin inhibitor |
| Answer» C. Autocatalytic activation of zymogen precursor | |
| 25. |
Same amino acid is coded by multiple codons d/t following - |
| A. | Degeneracy |
| B. | Frame-shift mutation |
| C. | Transcription |
| D. | Mutation |
| Answer» B. Frame-shift mutation | |
| 26. |
DNA repair defect is seen in - |
| A. | Xeroderma pigmentatosa |
| B. | Bloom's syndrome |
| C. | Ataxia telangiectasia |
| D. | All of the above |
| Answer» E. | |
| 27. |
Vitamin required for post translational modification of coagulants is: |
| A. | Vitamin B6 |
| B. | Vitamin K |
| C. | Vitamin A |
| D. | Vitamin C |
| Answer» C. Vitamin A | |
| 28. |
Insulin does not facilitate glucose uptake in the following except: |
| A. | Heart |
| B. | Liver |
| C. | Kidney |
| D. | RBC |
| Answer» B. Liver | |
| 29. |
Which of the following can be a homologous substitution for valine in hemoglobin? |
| A. | Glutamic acid |
| B. | Isoleucine |
| C. | Lysine |
| D. | Phenylalanine |
| Answer» B. Isoleucine | |
| 30. |
The major fate of glucose-6 Phosphate in tissue in a well fed state is: |
| A. | Conversion to glycogen |
| B. | Hydrolysis to glucose |
| C. | Conversion to ribulose 5 Phosphate |
| D. | Isomerization to fructose 6 Phosphate |
| Answer» B. Hydrolysis to glucose | |
| 31. |
Which one of the following is the complementary sequence of 5 TTAAGCTAC 3? |
| A. | 5 GTACGCTTAA 3 |
| B. | 5 TTAAGCGTAC 3 |
| C. | 5 CATGCGAATT 3 |
| D. | 5 AATTCGCATG 3 |
| Answer» B. 5 TTAAGCGTAC 3 | |
| 32. |
Components of 60s subunit of ribosome are - |
| A. | 18 S |
| B. | 28 S |
| C. | 23 S |
| D. | 16 S |
| Answer» C. 23 S | |
| 33. |
Which of the following does not cross the cell membrane: |
| A. | Glucose-6-phosphate |
| B. | Glucose |
| C. | Nitrous oxide |
| D. | Carbon monoxide |
| Answer» B. Glucose | |
| 34. |
Familial hypercholesterolemia is - |
| A. | HMG CoA reductase deficiency |
| B. | Deficient VLDL receptors |
| C. | Deficient LDL receptors |
| D. | Deficient HDL receptors |
| Answer» D. Deficient HDL receptors | |
| 35. |
True about Hybridoma - |
| A. | Immortalise myeloma cell |
| B. | Prior immunization is done |
| C. | Produce monospecific and monoclonal Ab |
| D. | All of the above |
| Answer» E. | |
| 36. |
Purpose of Gene therapy - |
| A. | Knock out of abnormal gene |
| B. | Introduction of viral gene |
| C. | Replacement of abnormal gene by normal gene |
| D. | Replacement of normal gene by abnormal gene |
| Answer» D. Replacement of normal gene by abnormal gene | |
| 37. |
Cytoplasmic process during processing is - |
| A. | Methylation of tRNA |
| B. | Attachment of CCA in tRNA |
| C. | 5' capping |
| D. | Poly(A) tailing |
| Answer» C. 5' capping | |
| 38. |
In TCA cycle, CO2 is released from - |
| A. | Isocitrate dehydrogenase |
| B. | Thiokinase |
| C. | Alpha ketoglutrate |
| D. | Citrate dehydrogenase |
| Answer» B. Thiokinase | |
| 39. |
The long and short arms of chromosomes are designated respectively as: |
| A. | m and q arms |
| B. | p and q arms |
| C. | l and s arms |
| D. | q and p arms |
| Answer» E. | |
| 40. |
NADPH oxidase deficiency causes - |
| A. | Chediakihigashi syndrome |
| B. | Chronic granulomatous disease |
| C. | Leucocyte adhesion defect type 1 |
| D. | Leucocyte adhesion defect type 2 |
| Answer» C. Leucocyte adhesion defect type 1 | |
| 41. |
Most commonly occurring amino acid in the collagen structure is - |
| A. | Serine |
| B. | Glycine |
| C. | Hydroxyproline |
| D. | Proline |
| Answer» C. Hydroxyproline | |
| 42. |
Boiled cabbage or rancid butter smelling urine is seen in ? |
| A. | Phemylketonuria |
| B. | Tyrosinemia |
| C. | Isovaleric Acidaemia |
| D. | Multiple carboxylase deficiency |
| Answer» C. Isovaleric Acidaemia | |
| 43. |
Elasticity of the corneal layer of skin is due to the presence of: |
| A. | Keratin |
| B. | Histidine |
| C. | Cysteine |
| D. | Lysine |
| Answer» B. Histidine | |
| 44. |
An amino acid not involved in urea synthesis is - |
| A. | Citrulline |
| B. | Ornithine |
| C. | Aspartic acid |
| D. | Arginine |
| Answer» E. | |
| 45. |
Dinitrophenol causes: |
| A. | Inhibition of ATP synthase |
| B. | Inhibition of electron transport |
| C. | Uncoupling of oxidation and phosphorylation |
| D. | Accumulation of ATP |
| Answer» D. Accumulation of ATP | |
| 46. |
MHC class II antigens are located on which of the following cells - |
| A. | Dendritic cell |
| B. | Platelets |
| C. | T-cell |
| D. | RBC |
| Answer» B. Platelets | |
| 47. |
Ferric chloride test in PKU gives: |
| A. | Blue |
| B. | Yellow |
| C. | Red |
| D. | Green |
| Answer» E. | |
| 48. |
Which of the following is an activator of LCAT - |
| A. | Apo E |
| B. | Apo AI |
| C. | Apo B 100 |
| D. | Apo B 48 |
| Answer» C. Apo B 100 | |
| 49. |
All of the following amino acids are converted to succinyl-CoA,Except: |
| A. | Valine |
| B. | Histidine |
| C. | Methionine |
| D. | Isoleucine |
| Answer» C. Methionine | |
| 50. |
Technique is used to identify known genetic loci - |
| A. | FISH |
| B. | RT-pcr |
| C. | Chromosomal painting |
| D. | Karyotyping |
| Answer» B. RT-pcr | |