MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Epimer combination is - |
| A. | D-mannose and D-talose |
| B. | D-glucose and D-fructose |
| C. | D-glucose and D-gulose |
| D. | D-glucose and D-mannose |
| Answer» E. | |
| 2. |
Vit K is needed for which of these post transational modification processes- |
| A. | Methylation |
| B. | Carboxylation |
| C. | Hydroxylation |
| D. | Transketolation |
| Answer» C. Hydroxylation | |
| 3. |
True about amino group of amino acid - |
| A. | Accepted by Alpha-ketoglutrate |
| B. | Funneled to L-Glutamate |
| C. | Prevents oxidative breakdown |
| D. | All of the above |
| Answer» E. | |
| 4. |
Thermo-stability in DNA is contributed mostly by |
| A. | A=T |
| B. | G equivalent C |
| C. | Molecular base |
| D. | Parallel arrangement |
| Answer» C. Molecular base | |
| 5. |
The following fatty acid does not belong to W6 series - |
| A. | Arachidonic acid |
| B. | Alpha linolenic acid |
| C. | Linoleic acid |
| D. | Gamma linolenic acid |
| Answer» C. Linoleic acid | |
| 6. |
Energy producing enzymes are located in |
| A. | Rough endoplasmic reticulum |
| B. | Ribosomes |
| C. | Golgi apparatus |
| D. | Mitochondria |
| Answer» E. | |
| 7. |
Amber codon refers to |
| A. | Mutant codon |
| B. | Stop codon |
| C. | Initiating codon |
| D. | Codon for more than one amino acids |
| Answer» C. Initiating codon | |
| 8. |
Which of the following aminoacids in a protein commonly acts as a potential O-Glycosylation site for attachment of an oligosacharide unit: |
| A. | Cysteine |
| B. | Glutamine |
| C. | Asparaginine |
| D. | Serine |
| Answer» E. | |
| 9. |
In dividing cells,spindle is formed by: |
| A. | Tubulin |
| B. | Ubiquitin |
| C. | Keratin |
| D. | Laminin |
| Answer» B. Ubiquitin | |
| 10. |
Binding of proteins to DNA is regulated by: |
| A. | Zinc |
| B. | Copper |
| C. | Nickle |
| D. | Selenium |
| Answer» B. Copper | |
| 11. |
In monoclonal antibody production, monoclonal cells are differentiated from ? |
| A. | Sensitized B cells |
| B. | Sensitized T cells |
| C. | Myeloma cell lines |
| D. | None of the above |
| Answer» D. None of the above | |
| 12. |
Heme synthesis requires - |
| A. | Ferrous iron |
| B. | Glycine |
| C. | Succhyl CoA |
| D. | All of the above |
| Answer» E. | |
| 13. |
True among all is - |
| A. | Lactose is positive regulator |
| B. | Catabolite repression is mediated by CRP |
| C. | Repressor is dimer and a positive regulator |
| D. | CRP is gratuitous inducer |
| Answer» C. Repressor is dimer and a positive regulator | |
| 14. |
CO2 is released in the step of TCA cycle- |
| A. | Citrate --->Cis-aconitate |
| B. | Isocitrate --->alpha-ketoglutarate |
| C. | Succinyl-COA --->Succinate |
| D. | Succinate --->Fumarate |
| Answer» C. Succinyl-COA --->Succinate | |
| 15. |
Which of the following substances acts to increase the release of Ca+from endoplasmic reticulum? |
| A. | 1.25-dihydroxy cholecalciferol |
| B. | Diacylglycerol |
| C. | Inositol triphosphate |
| D. | Parathyroid hormone |
| Answer» D. Parathyroid hormone | |
| 16. |
Aptamer is ? |
| A. | Antibodies |
| B. | Types of m-RNA |
| C. | Oligonucleotides |
| D. | Ribozymes |
| Answer» D. Ribozymes | |
| 17. |
Fluoride,used in the collection of blood samples for glucose estimation,inhibits the enzyme: |
| A. | Hexokinase. |
| B. | Glucokinase. |
| C. | Glucose-6-phosphatase. |
| D. | Enolase. |
| Answer» E. | |
| 18. |
Hyponatremia has no effect on the resting membrane potential because - |
| A. | The cell membrane is impermeable to Na+ |
| B. | ECF Na+ concentration is high |
| C. | Intracellular K+ concentration is high |
| D. | Equilibrium potential for Na+ is + 60 mV. |
| Answer» E. | |
| 19. |
Which receptors are present in liver for uptake of LDL |
| A. | Apo A and Apo E |
| B. | Apo E |
| C. | Apo B100 |
| D. | Apo E and Apo B100 |
| Answer» E. | |
| 20. |
All of the following are trypsin inhibitors,Except: |
| A. | Alpha - 1 - antoproteinase |
| B. | Alpha - 1 - antitrypsin |
| C. | Egg - white |
| D. | Enterokinase |
| Answer» E. | |
| 21. |
Positive signals for glycogen breakdown include increase in all of the following except - |
| A. | Cylic AMP |
| B. | Blood glucose |
| C. | Epinephrine |
| D. | Both B and C |
| Answer» C. Epinephrine | |
| 22. |
Which of the following is the correct sequential order in which the given enzymes of Kreb's cycle are formed after a molecule of acetyl CoA enters the cycle - |
| A. | Ketoglutarate, Oxaloacetate, Citrate |
| B. | Citrate, Oxaloacetate, Ketoglutarate |
| C. | Oxaloacetate, Ketoglutarate, Citrate |
| D. | Citrate, Ketoglutarate, Oxaloacetate |
| Answer» E. | |
| 23. |
Creatinine is synthesised from - |
| A. | Ornithine and glycine |
| B. | Thymine and ornithine |
| C. | Glycine, arginine and methioine |
| D. | Glycine and methioine |
| Answer» D. Glycine and methioine | |
| 24. |
Compounds with large amount of carbohydrate and small amount of protein - |
| A. | Glucosaminoglycan |
| B. | Glycoprotein |
| C. | Glycocalyx |
| D. | Proteoglycan |
| Answer» E. | |
| 25. |
Probe used in western blot - |
| A. | DNA |
| B. | t-RNA |
| C. | Antibody |
| D. | M-RNA |
| Answer» D. M-RNA | |
| 26. |
Blood is not a newtonian fluid because: |
| A. | Viscosity changes with velocity |
| B. | Viscosity does not changing with velocity |
| C. | Density changes with velocity |
| D. | Density does not change with velocity |
| Answer» B. Viscosity does not changing with velocity | |
| 27. |
Photolyase helps in - |
| A. | Protein synthesis |
| B. | None |
| C. | DNA repair |
| D. | DNA replication |
| Answer» D. DNA replication | |
| 28. |
In PCR - |
| A. | Thermolabile enzyme |
| B. | Non specific |
| C. | Thermostable enzyme is needed |
| D. | 211 copies formed after 'n' numbers of multiple |
| Answer» D. 211 copies formed after 'n' numbers of multiple | |
| 29. |
Apart form occurring in nucleic acids, pyrimidines are also found in - |
| A. | Theophylline |
| B. | Theobromine |
| C. | Flavin mononucleotide |
| D. | Thiamine |
| Answer» E. | |
| 30. |
True about Glutathione reductase: |
| A. | Important in methemoglobinemia |
| B. | Sulphur containing enzyme |
| C. | All |
| D. | Free radical scavenger |
| Answer» E. | |
| 31. |
Aminoacyl t-RNA is required for all except: |
| A. | Cystine |
| B. | Lysine |
| C. | Hydroxyproline |
| D. | Methionine |
| Answer» D. Methionine | |
| 32. |
Vitamin B12 acts as co-enzyme to which one of the following enzymes? |
| A. | Homocysteine methyl transferase |
| B. | Isocitrate dehydrogenase |
| C. | G-6-P dehydrogenase |
| D. | Glycogen synthase |
| Answer» B. Isocitrate dehydrogenase | |
| 33. |
Hemoglobin acts as a buffer because of - |
| A. | Glycine |
| B. | Histidine |
| C. | Alanine |
| D. | Valine |
| Answer» C. Alanine | |
| 34. |
True about G protein coupled receptors is - |
| A. | All the three subunits alpha, beta and gama should bind to each other for G protein to act |
| B. | G proteins bind to hormones on the cell surface |
| C. | G protein is bound to GTP in resting state |
| D. | G protein act as inhibitory and excitatory because of difference in alpha subunit |
| Answer» E. | |
| 35. |
Increased level of lipoprotein(a) predisposes to - |
| A. | Antherosclerosis |
| B. | Liver cirrhosis |
| C. | Pancretitis |
| D. | Nephrotic syndrome |
| Answer» B. Liver cirrhosis | |
| 36. |
An essential amino acid in man is - |
| A. | L-serine |
| B. | L-proline |
| C. | L-methionine |
| D. | L-tyrosine |
| Answer» D. L-tyrosine | |
| 37. |
Hexokinase is a - |
| A. | Oxidoreductase |
| B. | Oxidase |
| C. | Transferase |
| D. | Reductase |
| Answer» D. Reductase | |
| 38. |
Aneuploidy is due to |
| A. | Non-disjunction at meiosis |
| B. | Mosaicism |
| C. | Deletion |
| D. | Translocation |
| Answer» B. Mosaicism | |
| 39. |
At the physiological pH the DNA molecules are: |
| A. | Positively charged |
| B. | Negatively charged |
| C. | Neutral |
| D. | Amphipathic |
| Answer» C. Neutral | |
| 40. |
An Immunoglobulin molecule represents the following level of organized protein structure: |
| A. | Tertiary structure |
| B. | Quartenary structure |
| C. | Primary structure |
| D. | Secondary structure |
| Answer» C. Primary structure | |
| 41. |
Fluoride inhibits which enzyme |
| A. | Pyruvate kinase |
| B. | Succinyl dehydrogenase |
| C. | Enolase |
| D. | Aldolase |
| Answer» D. Aldolase | |
| 42. |
Thiamine level is best monitored by: |
| A. | G6PD activity |
| B. | Reticulocytosis |
| C. | Transketolase level in blood |
| D. | Thiamine level in blood |
| Answer» D. Thiamine level in blood | |
| 43. |
Anticodon is located on ? |
| A. | m-RNA |
| B. | t-RNA |
| C. | DNA |
| D. | r-RNA |
| Answer» C. DNA | |
| 44. |
True about telomerase or telomere is - |
| A. | They are present at the ends of eukaryotic chromosome |
| B. | DNA depends RNA polymerase |
| C. | DNA polymerase |
| D. | All of the above |
| Answer» B. DNA depends RNA polymerase | |
| 45. |
Which of the following statements about protein structure is correct? |
| A. | The extended beta-configuration is not found in globular proteins |
| B. | The stability of the alpha helix is mainly due to hydrophobic interactions |
| C. | Globular proteins tend to fold into configurations that keep hydrophobic side chains in the interior of the molecule |
| D. | The primary structure of a peptide does not influence the formation of native three dimensional configuration |
| Answer» D. The primary structure of a peptide does not influence the formation of native three dimensional configuration | |
| 46. |
Maximum source of linoleic acid is - |
| A. | Coconut oil |
| B. | Sunflower oil |
| C. | Palm oil |
| D. | Vanaspati |
| Answer» C. Palm oil | |
| 47. |
Somatic mutations involves - |
| A. | Frame-shift alteration in coding nucleotides |
| B. | Trinucleotide repeat mutations |
| C. | Non-sense alteration of DNA |
| D. | All of the above |
| Answer» E. | |
| 48. |
In synthesis of fatty acids energy is supplied by - |
| A. | GTP |
| B. | NADPH |
| C. | NAD |
| D. | FAD |
| Answer» C. NAD | |
| 49. |
Accumulation of sphingomyelin in phagocytic cells is feature of |
| A. | Gauchers disease |
| B. | Niemann pick ds |
| C. | Tay sachs disease |
| D. | Downs syndrome |
| Answer» C. Tay sachs disease | |
| 50. |
Cholesterol structurally belongs to molecule - |
| A. | Urea |
| B. | Peptide |
| C. | Steroid |
| D. | Carbohydrate |
| Answer» D. Carbohydrate | |