MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Bilirubin is absent in urine because it is - |
| A. | Not filterable |
| B. | Lipophilic |
| C. | Distributed in the body fat |
| D. | Conjugated with glucoronide |
| Answer» C. Distributed in the body fat | |
| 2. |
Which of the following is not a part part of DNA correction mechanism ? |
| A. | Nucleoside correction |
| B. | Pre replication |
| C. | Post replication |
| D. | Base pair correction |
| Answer» B. Pre replication | |
| 3. |
Which of the following is a debranching enzyme - |
| A. | Glucose-6-phosphatase |
| B. | Glycogen synthetase |
| C. | Amylo 1,4,--1,6 transglycosylase |
| D. | Amylo (1,6) glucosidase |
| Answer» E. | |
| 4. |
True about silent mutation in gene - |
| A. | No change in mRNA |
| B. | No expression of protein |
| C. | No change in expression of protein |
| D. | All of the above |
| Answer» D. All of the above | |
| 5. |
True statement regarding covalent bonds is: |
| A. | Electrons have same spin |
| B. | Electrons have opposite spin |
| C. | They are weak bonds |
| D. | None of the above |
| Answer» C. They are weak bonds | |
| 6. |
A destitute woman is admitted to the hospital with altered sensorium and dehydration;urine analysis shows mild proteinuria and no sugar;what other test would be desirable: |
| A. | Rothera |
| B. | Fouchet |
| C. | Benedicts |
| D. | Hays |
| Answer» B. Fouchet | |
| 7. |
The 40 nm in between the tropocollagen molecule in collagen which serve as the site of bone formation is occupied by hich of the following - |
| A. | Ligand moiety |
| B. | Carbohydrate |
| C. | Fe+++ |
| D. | Ca++ |
| Answer» E. | |
| 8. |
The most essential fatty acid is |
| A. | Linoleic acid |
| B. | Linolenic acid |
| C. | Arachidonic acid |
| D. | Palmitic acid |
| Answer» B. Linolenic acid | |
| 9. |
All participate in Fatty acid synthesis except - |
| A. | Transcylase |
| B. | Dehydrogenase |
| C. | Hydratase |
| D. | Reductase |
| Answer» C. Hydratase | |
| 10. |
A normal baby is able to self spoon feed at the age of - |
| A. | 18 months |
| B. | 12 months |
| C. | 9 months |
| D. | 6 months |
| Answer» B. 12 months | |
| 11. |
Restriction fragment length polymorphism is used for: |
| A. | Synthesis of nucleic acid |
| B. | Detecting proteins in a cell |
| C. | Analysis of chromosome structures |
| D. | DNA estimation |
| Answer» D. DNA estimation | |
| 12. |
Which of the following is not a post transcriptional modification of RNA? |
| A. | 3' polyadenylation |
| B. | Glycosylation |
| C. | Splicing |
| D. | 5' capping |
| Answer» C. Splicing | |
| 13. |
A protein solution on heating forms a precipitate at about 400c which redissolves at higher temperature.This solution is likely to contain: |
| A. | Complement |
| B. | Alpha-2-macroglobulins |
| C. | Bence Jones Protein |
| D. | Cryoglobulins |
| Answer» D. Cryoglobulins | |
| 14. |
Which of the following represents the most chracteristic function of Type II Restriction Enzymes: |
| A. | Prevent supercoiling |
| B. | Cut DNA at palindromic sites |
| C. | Prevent folding of proteins |
| D. | Remove formed DNA |
| Answer» C. Prevent folding of proteins | |
| 15. |
Which moiety of Haemoglobin molecule binds 2,3,DPG at pH 7.0 |
| A. | Amino terminal |
| B. | Carboxylic terminal |
| C. | Sulphydryl terminal |
| D. | Alcoholic terminal |
| Answer» B. Carboxylic terminal | |
| 16. |
Hormone sensitive lipase is inhibited by ? |
| A. | Insulin |
| B. | Glucagon |
| C. | ACTH |
| D. | Catecholamines |
| Answer» B. Glucagon | |
| 17. |
In which of the following conditions the level of creatinine kinase-1 increases? |
| A. | Brain Ischemia |
| B. | Myocardial Ischemia |
| C. | Electrical cardioversion |
| D. | Kidney damage |
| Answer» B. Myocardial Ischemia | |
| 18. |
Which of the following does not contain keratin - |
| A. | Carrot |
| B. | Spinach |
| C. | Potato |
| D. | Tomato |
| Answer» D. Tomato | |
| 19. |
Gout is a disorder of: |
| A. | Oxalate metabolism |
| B. | Protein metabolism |
| C. | Purine metabolism |
| D. | Pyrimidine metabolism |
| Answer» D. Pyrimidine metabolism | |
| 20. |
All are true about glutathione, except |
| A. | It converts hemoglobin to methemoglobin |
| B. | It is a tripeptide |
| C. | It is co-factor of various enxymes |
| D. | It conjugates xenobiotics |
| Answer» B. It is a tripeptide | |
| 21. |
The specialized mammalian tissue/organ in which fuel oxidation serves not to produce ATP but to generate heat is: |
| A. | Skeletal muscle |
| B. | Adrenal gland |
| C. | Heart |
| D. | Brown adipose tissue |
| Answer» E. | |
| 22. |
Urea is produced by the enzyme - |
| A. | Uricase |
| B. | Urease |
| C. | Glutaminase |
| D. | Arginase |
| Answer» E. | |
| 23. |
Metabolite of progesterone is urine - |
| A. | Pregnenolone |
| B. | 17 hydroxypregnenolone |
| C. | Pregnendiol |
| D. | Pregnentriol |
| Answer» D. Pregnentriol | |
| 24. |
Hypolipidemic agent acts on - |
| A. | HMG CoA oxygenase |
| B. | HMG CoA hydratase |
| C. | HMG CoA reductase |
| D. | HMG CoA synthetase |
| Answer» D. HMG CoA synthetase | |
| 25. |
The electron flow in Cytochrome C oxidase can be blocked by - |
| A. | Antimycin-A |
| B. | Rotenone |
| C. | Actinomycin |
| D. | Cyanide |
| Answer» E. | |
| 26. |
Which of the following enzymes catalyze reactions in the biosynthesis of both catecholamines and indoleamines (serotonin)? |
| A. | Dopamine beta-hydroxylase |
| B. | Phenyl ethanolamine N-methyl transferase |
| C. | Aromatic amino acid decarboxylase |
| D. | Tryptophan hydroxylase |
| Answer» D. Tryptophan hydroxylase | |
| 27. |
Difference between reversible and irreversible reaction is - |
| A. | Temperature |
| B. | Entropy |
| C. | Amount of heat production |
| D. | Work done |
| Answer» E. | |
| 28. |
Components of chromosomes are - |
| A. | mRNA |
| B. | rRNA |
| C. | DNA |
| D. | tRNA |
| Answer» D. tRNA | |
| 29. |
Which of the following components will not be present after action of salivery amylase? |
| A. | Isomaltose |
| B. | Maltose |
| C. | Maltotriose |
| D. | Fructose |
| Answer» E. | |
| 30. |
Signal peptides are synthesized in - |
| A. | Free ribosomes |
| B. | ER |
| C. | Golgi body |
| D. | Membrane bond ribisomes |
| Answer» E. | |
| 31. |
Which of the following is not true in relation to glycoproteins - |
| A. | Are proteins to which oligosaccharide are covalently attached |
| B. | The cabohydrate units of glycoprotein have several different |
| C. | Carbohydrate content is same but proteins are different |
| D. | All of the above |
| Answer» D. All of the above | |
| 32. |
The enzyme used in polymerase chain reaction(PCR) is - |
| A. | Inorganic ion |
| B. | Inorganic metal |
| C. | Thermostable enzyme |
| D. | Enzyme stabiliser |
| Answer» D. Enzyme stabiliser | |
| 33. |
In cholesterol synthesis, which is rate limiting amino acid - |
| A. | 7 alpha hydroxylase |
| B. | Phosphofructokinase |
| C. | HMG CoA reductase |
| D. | HMG CoA synthetase |
| Answer» D. HMG CoA synthetase | |
| 34. |
Methods of fusing two cell in genetic recombination technique include all of the following techniques, Except: |
| A. | Fusion mediated by viral transformation |
| B. | Fusion mediated by altering membrane viscocity |
| C. | Fusion mediated by Ethylene Glycol |
| D. | Fusion mediated by Electric current |
| Answer» D. Fusion mediated by Electric current | |
| 35. |
Panthothenic acid is coenzyme of which of the following reaction - |
| A. | Decarboxylation |
| B. | Acetylation |
| C. | Dehydrogenation |
| D. | Oxidation |
| Answer» C. Dehydrogenation | |
| 36. |
In chronic alcoholism the rate limiting component for alcohol metabolism excluding enzymes is - |
| A. | NAD |
| B. | NADP |
| C. | FAD |
| D. | FADH |
| Answer» B. NADP | |
| 37. |
DNA polymerase have - |
| A. | 5' - 3' exonuclease activity |
| B. | 5' - 3' polymerase activity |
| C. | 3' - 5' exonuclease activity |
| D. | All of the above |
| Answer» E. | |
| 38. |
In RNA, gene during processing undergoes all, except - |
| A. | Nucleoside modification |
| B. | Nucleoside cleavage |
| C. | Chemical hydrolysis |
| D. | Terminal addition |
| Answer» D. Terminal addition | |
| 39. |
All are true about Bita-oxidant except - |
| A. | Carnitine palmitoyl transferase I is present in outer mitochondrial membrane |
| B. | Activation of FA is a must |
| C. | FA activation requires 2ATP |
| D. | Carnitine palmitoyl transferase II is present in outer mitochondrial matrix |
| Answer» E. | |
| 40. |
Ketone body production occurs in ? |
| A. | Cytoplasm |
| B. | Mitochondria |
| C. | Golgi body |
| D. | Nucleus |
| Answer» C. Golgi body | |
| 41. |
True about competitive inhibition of enzyme - |
| A. | Increase Vmax |
| B. | No change in km and Vmax |
| C. | Increase km |
| D. | Decrease km |
| Answer» D. Decrease km | |
| 42. |
The conjugation of bilirubin to glucuronic acid in the liver: |
| A. | Converts a hydrophilic compound to a hydrophobic one |
| B. | Converts a hydrophobic compound to a hydrophilic one |
| C. | Enables the bilirubin molecule to cross the cell membrane |
| D. | Is increased during neonatal jaundice |
| Answer» C. Enables the bilirubin molecule to cross the cell membrane | |
| 43. |
Aromatic ring is present in - |
| A. | Glycine |
| B. | Arginine |
| C. | Phenylalanine Glycine |
| D. | Phenylalanine |
| Answer» E. | |
| 44. |
Xeroderma pigmentation is caused due to a group of closely related abnormalities in - |
| A. | Mismatch repair |
| B. | Base excision repair |
| C. | Nucleotide excision repair |
| D. | SOS repair |
| Answer» D. SOS repair | |
| 45. |
Presence of only bilirubin glucuronide in urine but not urobilinogen indicates: |
| A. | Hemolytic jaundice |
| B. | Hepatocellular disease |
| C. | Crigler-Najjar syndrome type II |
| D. | Obstructive jaundice |
| Answer» E. | |
| 46. |
RNA with Enzymatic Activity - |
| A. | Peptidase |
| B. | Peptidyl transfearase |
| C. | Cytidine deaminase |
| D. | Aminoacyl tRNA synthesis |
| Answer» C. Cytidine deaminase | |
| 47. |
During replication of DNA,which one of the following enzymes polymerizes the Okazaki fragments? |
| A. | DNA Polymerase II |
| B. | DNA Polymerase I |
| C. | RNA Polymerase I |
| D. | DNA Polymerase III |
| Answer» E. | |
| 48. |
What will happen to DNA if salt is added to it - |
| A. | Not affect Tm |
| B. | Both Incrase and decrease in Tm depending on concentration of salt |
| C. | Incrase melting point (Tm) |
| D. | Decrease Tm |
| Answer» D. Decrease Tm | |
| 49. |
Zinc is a cofactor for - |
| A. | a-keto glutarate dehydrogenase |
| B. | Alcohol dehydrogenase |
| C. | Pyruvate dehydrogenase |
| D. | Pyruvate decarboxylase |
| Answer» C. Pyruvate dehydrogenase | |
| 50. |
Oxaloacetate Acetyl CoA - Citrate CoASH. This reaction is - |
| A. | Irreversible |
| B. | Reversible |
| C. | Competitive |
| D. | Can be reversed by catalase |
| Answer» B. Reversible | |